Zhang Yingquan, who was born in the county order, gave up the official to practice medicine, returned to his hometown Xingzhou, and founded Yuxingtang. From Zhang Bingshan to Zhang Zaijing, and then to Zhang Guixin and Zhang Ziyu, the Zhang family has become a famous doctor from generation to generation. Zhang Bingshan has excellent wisdom, became famous as a young man, but he was weak and sickly, and when he was dying, he was taken away by a Taoist priest with a crane hair and a childish face. Zhang Zaijing developed and expanded Yuxingtang, but he was in a relationship with Zhao Yushu. Zhao Yushu was originally the daughter of the Zhao family's bone museum, she could heal and martial arts, she could go to the hall, beat the hooligans, and after becoming Zhang Zaijing's wife, she was willing to be the woman behind him. Gentle and beautiful, Zhang Ziyu, who has studied traditional Chinese and Western medicine, is full of ups and downs in her emotional path, facing an arbitrary father and wise lover, her heart is like a double silk net, with thousands of knots. Song Baoliang, who is known as a strange doctor, was framed and imprisoned, and also wandered to Yuxing Hall and became a famous doctor in the hall. The changes of the past hundred years have changed the fate of the owners of Yuxing Hall. Love, affection, friendship...... composes the ups and downs of the medical road.