"Dr. Sun, I'm Kaoru Kobayashi. Before Sun Lien could speak, he heard the other end of the phone, and Kobayashi Kaoru said first, "I am now with Mr. Aaron, the senior vice president of Shire Pharmaceuticals, and this phone call is hands-free." ”

"Mr. Kobayashi, we need some help. Sun Lien didn't have time to ask why the phone was turned on on speakerphone, so he said directly, "Our hospital admitted a patient who had symptoms of malignant hyperthermia during the operation. Our hospital does not have a stockpile of dantrolene, a special drug for the treatment of malignant hyperthermia, does your company have a similar product? Can you provide us with some urgently?"

"Dantrolorine is a drug produced by an American company, and the company has not set foot in related fields. Kobayashi Feng first vetoed Sun Lien's request, and then pretended to be curious and asked, "Danqu Lorraine has been around for many years, why doesn't your hospital have a reserve?"

Sun Lien sighed, "This drug is not produced in China and has not passed the CFDA certification. Even if you go through the green channel, it will take more than two years for a batch of drugs to arrive at the post and wait for the review to be completed. The validity period of the drug storage is only three years, and it will basically become invalid when it enters the country. These drugs are expensive to import, and hospitals can't afford to spend a lot of money to store drugs that are about to expire. ”

"This is the case with many orphan drugs, which cannot be sold immediately in the mainland market due to the impact of some processes and regulations. This is not conducive to drug R&D companies recovering R&D costs. Kobayashi Feng followed Sun Lien's words, but it seemed that there was some inconsistency in the preamble. "Speaking of which, Dr. Sun, this is the first rare case you've encountered?"

"I've probably been out of luck lately. Sun Lien smiled a little embarrassed on the other end of the phone, "Although our hospital is a large emergency center, emergency patients in the vicinity will be sent here." But lately it's been a bit much. ”

"I don't think so. "With the advancement of medicine, the incidence of many so-called rare diseases is actually much higher than we imagined. It's just that these patients have not been diagnosed before, or doctors don't know enough about these diseases, so they are misdiagnosed as other diseases. ”

"If you have any questions about the medicines you need, I will ask the Greater China Manager of the Company to contact you directly and do everything I can to provide medicines to your hospital. Kobayashi Feng changed the topic, "But after all, this medicine is not a product of the Disdain, and I dare not guarantee that it can be provided in time." But I assure you that the whole community will do their best. ”

Sun Lien was overjoyed when he heard this, "Thank you so much, Mr. Kobayashi." ”

Hanging up the phone, Kobayashi looked at Aaron with a smile, "Mr. Aaron, as you heard, the sales of drugs for rare diseases have a lot to offer in the Chinese market!"

"A phone call alone doesn't tell the story, Mr. Kobayashi. Aaron spoke with a pride peculiar to the elite of Western society, "It's easy to arrange for an actor to call at a certain moment, isn't it?"

"Of course I can arrange actors, but one actor can't do those things. Kobayashi Feng smiled slightly, he knew these Westerners who thought highly of themselves too well. He glanced at his secretary, who respectfully took out a stack of printed papers from his bag.

"These are summaries of all the patients of the 'actor' you just heard from in the last month. "Kobayashi Feng spent a lot of money to buy Zhao Weihua, and the picture is the ability to make a decision at such a time. "I can vouch for the authenticity of these documents, you can see how many rare diseases a doctor diagnosed in a month in a Chinese hospital. ”

Aaron first flipped through the record with some perfunctory looks, and then his face slowly became serious, and the speed of reading the cases became slower and slower.

"You know, the emergency department of this hospital alone can admit more than 200,000 people a year. Kobayashi Feng struck while the iron was hot and continued, "There are six hospitals of the same level in the city of Ningyuan. He looked at Aaron, leaned forward, and said with some excitement, "Think about it, Mr. Aaron." One city has more than 1.2 million patients in a year! How many people are there in Dublin? Two million, three million? There are hundreds of cities of the same size or even more in China! Those patients, those patients, those markets!"

"I ...... We can start an experiment on the same scale in India......" Aaron said with beads of sweat on his head, and he wanted to fight for a little more for himself and the company's shareholders, "The Indian government has no restrictions on us conducting clinical trials......

"What is the price?Mr. Aaron?" Kobayashi looked at Aaron with a smile, "Your company has never conducted clinical trials in India since its establishment, and the reason is clear to everyone - once clinical trials start in India, Indian pharmaceutical companies will inevitably be able to obtain the synthesis method of the experimental drug, and can imitate the product on a large scale." The market for your products is already very small, and if you attract competition from Indian pharmaceutical companies, you won't be able to sustain it for a long time, right?"

"Not to mention anything about the Indian market. The number of patients who can afford to pay the premium price of your products is small, and most of them live in Europe or the United States. People who still live in India and rely on the local healthcare system have little to no ability to pay. Kobayashi's body is more advanced, "Therefore, it is not beneficial for you to open up the Indian market at all, except for the challenges of your own products." But China is different. Kobayashi waved his hand fiercely, "Chinese are much richer than Indians." And they will pay for sick family members on a family basis. What's more, China's attitude towards rare disease drug policy has changed. ”

"Now that they've changed, we can enter the Chinese market on our own. Aaron was almost powerless to refute, he wiped the sweat on his head and said to his neck, "China welcomes foreign investment to build factories, we can invest directly!"

"And then?" said Kobayashi, sitting back and smiling, "to set up a factory in China and promote the medicine little by little?" If it weren't for a large pharmaceutical group like Takeda, it would be impossible for you to apply for clinical trials. If your medication doesn't fit into the social insurance or commercial insurance paylist, it's still a dead end. He smiled and waved his hand, "Do you want the Chinese market? $64 billion, and full support from Takeda – trust me, we're in good faith. ”

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"How is it?" Cao Xin listened to Sun Lien hang up the phone and asked anxiously, "Is there any medicine?"

"Takeda said that dantrolene is produced by American companies, and they are not involved in related fields. But I will give my full support to help find medicine. Sun Lien showed a helpless expression, "The problem is that even the president of Takeda said that he can't guarantee that he can find the medicine in time." ”

Dr. Cao scratched his head angrily, "This is troublesome. "Without dantrolene, that means that the patient's temperature can only be controlled by physical means. It's okay for patients with 389 or even 40 degrees, but it's really hard to say how much effect a malignant fever can have on an ice blanket or something like that.

"Let's do what we can, and the rest can only depend on whether the patient's life is good or not. Sun Lien sighed. He thought about it for a moment and made another phone call to go out.

Shen Qingmei was in a meeting, she was shocked when she saw the call on her mobile phone, and she didn't care about the many executives sitting in the conference room, picked up her mobile phone and walked out of the conference room.

"Doctor Sun?" her voice trembled, "Yes...... What's the matter?"

Only then did Sun Lien realize what Shen Qingmei was worried about, and hurriedly explained, "Chen Wen is fine, don't worry." I'm calling now to ask for your help. ”

Knowing that everything was fine with his baby daughter, Shen Qingmei breathed a sigh of relief. After listening to Sun Lien's search for medicine, she pondered for a moment and asked, "I may have a way to find medicine, but ...... Are you sure you can use it on your patients?"

Sun Lien replied with some confusion, "It should be...... It's a miracle drug, and if you don't, it's dangerous. ”

"Doctor Sun, you shouldn't have seen the news for a long time, right?" Shen Qingmei sighed, "Some time ago, there was a doctor who got into a lot of trouble because he helped a patient introduce foreign generic drugs. ”

Sun Lien covered the phone and repeated Shen Qingmei's words to Cao Xin and asked, "Brother Cao, do you know this?"

"Nothing to worry about. Cao Xin glanced at Sun Lien and said, "With Dean Song on top, besides, this kind of emergency is an emergency, and the family has already approved it, no problem." ”

Sun Lien nodded and conveyed Cao Xin's words to Shen Qingmei. "Mr. Shen, human life is at stake, I'm sorry for you. ”

"Okay. Shen Qingmei was about to hang up the phone, but suddenly asked, "Have you contacted Takeda Pharmaceutical about this medicine?"

"I just spoke to Mr. Yutaka Kobayashi. Sun replied honestly, "He is meeting with Mr. Aaron, senior vice president of Shire Pharmaceuticals. ”

Shen Qingmei was shocked when he heard this, and hurriedly asked, "When did it start?"

"I don't know. Sun Lien scratched his head, "But when I called just now, Kobayashi Feng was talking to me on hands-free." ”

Hands-free?Shen Qingmei grasped the point. "Did you mention in the call that it is difficult for orphan disease drugs to enter the Chinese market?"

Sun Lien looked around, and after making sure that Shen Qingmei was not nearby, he said in confusion, "That's right......"

"Doctor Sun, this medicine is on me!" Shen replied with a smile, "This news is very important to me, thank you!"

Hanging up the phone, Shen Qingmei walked into the conference room with the sound of whirring wind. She waved her hand to the many executives in the room, "The acquisition negotiations between Takeda Pharmaceutical and Shire Pharmaceuticals have entered the final stage, and Takeda has come up with the Chinese market ......" She glanced around at her executives, "There is no need to discuss it, the financial services department will follow up immediately, and each subsidiary must withdraw 60% of the existing funds into the financial services department within three days." She made a decision in high spirits, "Takeda's mouthful of fat, I Yuhua must eat a big bite!"

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Shen Qingmei is a very decisive woman. Only fifteen minutes later, Sun Lien received a call, and Danqu Lorraine, who was in a hurry to save people, was found. The Macao Red Cross Society transferred two boxes of dantrolene to the Mainland Red Cross Society through the green channel, and the chartered flight of Yuhua Group took off directly from Macao to deliver the life-saving medicine to Ningyuan. The plane is preparing to take off and is expected to arrive at Ningyuan International Airport in two hours and 30 minutes.

"Great. Dr. Cao breathed a sigh of relief that with dantrolene, the mortality rate of patients could drop directly from 75 percent to about 5 percent. While still dangerous, at least the odds of surviving are greatly increased. He breathed a sigh of relief, then patted Sun Lien on the shoulder and said, "It's really troublesome for you." ”

It is taboo for other people in society to use personal relationships for free because of strangers' affairs. But for the doctors, this action is not something to think about at all. If you trouble others, you can save a life, even if you owe a favor, it is very cost-effective.

Dr. Cao and Sun Lien hurriedly said a few more words, and then immediately left the ninth consultation room - although the operating room had been notified, it was positive for the patient to end the operation as soon as possible and move to full physical cooling. Now is not the time to add knowledge to the younger brother and disciple of the hand, Dr. Cao must rush to the operating room immediately to assist the surgeon to complete the operation as soon as possible.

Sun Lien stretched out his arm, and then saw the new patient triage information on the screen. He pressed the call button and said to the small microphone on the table, "Li Lifen, Li Lifen patient, please come to the ninth consultation room." ”

The woman with a sleek-faced face walked in. She smiled a somewhat timid smile at Sun Lien.

"Hello. Sun Lien looked down for a pen, ready to make a record, he didn't raise his head and asked, "Where are you uncomfortable?"

"I, I want to prescribe a little painkiller. Li Lifen said in a low voice, "I have a toothache." ”

Sun Lien looked up and saw that Li Lifen's head showed a string of status bars, "Li Lifen, female, 57 years old, mild myocardial infarction, mild starvation ketosis." ”

Anyway, now that he sees the word "infarction", Sun Lien is in a cold sweat, and this time is no exception. He looked at Li Lifen's face, looked up and down for a while, and then asked cautiously, "Do you feel a toothache?"

"I ......" Li Lifen seemed to want to say something, but finally shook her head. "I just have a toothache, doctor, you can do it, just prescribe me some painkillers. ”

Mild starvation ketosis meant that Li Lifen had been unable to eat enough for a long time. This symptom, which should theoretically be extinct in modern China, is now beginning to appear in the cities. Many young women who have been over-dieting for a long time in order to lose weight have developed the disease. But Li Lifen doesn't look like the kind of person who would lose weight for the sake of being in shape. The status bar didn't indicate an eating disorder, and her hunger ketosis was probably really due to not having enough to eat.

Sun Lien asked tentatively, "What did you eat at night?"

Li Lifen was stunned for a moment, and then said in a covert manner, "I ate, I ate a lot." I ate meat, rice, potatoes, ......," she said, with a pained look on her face, "Doctor, you can prescribe me some medicine." ”

If it weren't for the status bar, Sun Lien would have thought that Li Lifen might be a painkiller addict. He lowered his head and wrote a few random strokes in his notebook, his mind quickly turned, and then raised his head and said, "It's okay to prescribe painkillers, but I have to do an electrocardiogram for you first." "Mild starvation ketosis isn't immediately life-threatening, but heart attack is different. Sun Lien decided to solve the most pressing problems first.

"I ......" Li Lifen looked like she wanted to refuse, but Sun Lien immediately interjected, "The cost of the examination is included in the outpatient clinic, let's go, I'll accompany you to have a checkup." You can rest assured, the ECG does not hurt at all, and the results are fast. As soon as the test results come out, I'll prescribe painkillers to you, okay?" he coaxed Li Lifen out of the ninth consultation room, and then walked towards the emergency room.