Are there any side effects of ornidazole? Yes. But Qian Aiwu's coma must have been due to ornidazole? Not necessarily.

As an antibiotic that has been widely used in clinical practice for many years, the safety of ornidazole is quite guaranteed. However, because of its safety, there is a lack of relevant research on the mechanism and effect of antibiotics, and the understanding of the side effects of this antibiotic is still limited to rough observation and statistics.

For a patient who cannot find a cause, any possible suspicion of a target should be taken seriously. In Qian Aiwu's case alone, the main reason for using ornidazole is to better fight Clostridium infection. Under the premise that patients may have serious adverse reactions, it is logical to switch to other antimicrobial drugs.

Xu Yourong went to the pharmacy department for this matter.

After hanging up the phone, Xu Yourong continued to consult, "So, your suggestion is to switch to vancomycin?"

The clinical pharmacists nodded, and this advice was the standard response. For Clostridial infection, doctors have three medications that doctors can use, following the standard treatment protocol of the US Food and Drug Administration (FDA). They are nitroimidazole derivatives antibiotics represented by metronidazole and ornidazole, vancomycin, and fedamycin, which is still in clinical trials in China.

Of course, when ornidazole may have serious side effects, metronidazole is naturally excluded from the list of uses. Non-damomicin has not yet been marketed in China, and even if the experimental group that is conducting the trial is contacted, it is far away from the water to save the fire. The only reasonable option is vancomycin.

But vancomycin, like imipenem cilastatin sodium, which has been applied to Qian Aiwu, is an antibiotic that is being used under control. In order to prevent the emergence of drug-resistant bacteria, the latest and most powerful antibiotic applications need to be approved by the department head first. If two or more control antibiotics are used at the same time, approval from the Department of Pharmacy and the Department of Infectious Diseases is required.

"It's okay for us to approve it. Director Han Wenping looked at the patient's medical record report brought by Xu Yourong, and first expressed his attitude, "This patient's condition is more serious, and there is a high possibility of adverse reactions to ornidazole." The application of vancomycin, we have no opinion on the pharmacy department. ”

The doctor in the infectious disease department was a little embarrassed, "Doctor Xu, it's not that we delayed the time and deliberately stuck you, it's just that Director Huang went to the city to participate in this year's summer epidemic prevention work meeting, and he hasn't come back yet." And we are also turned off when we call, and we really can't get in touch. ”

Director Huang is the chief director of the Department of Infectious Diseases, and his attitude directly determines the attitude of the entire Department of Infectious Diseases.

"It doesn't matter. Before Xu Yourong spoke, Han Wenping spoke first, "According to the estimation of the medication time, her next medication should be around six o'clock in the afternoon today - six o'clock in the afternoon, Director Huang should come back anyway." Let's prepare the medicine first, just wait for Director Huang to come and sign it. If Director Huang can't come, he can also approve the medication through phone calls and recordings first, and come back tomorrow to make up for a procedure. ”

After he finished speaking, he looked at the silent conference room and coughed lightly, "I am also a person who has an old mother and a daughter." ”

This explanation is very revealing. The doctors in the room were all smiling, smiling and nodding to each other, as if they were conveying a thought to their colleagues through their eyes and movements, "I'll just say it!"

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The liver transplant is finally over.

This extremely complex operation, which started at the same time and lasted for more than five hours at most, has finally come to an end. As the initial donor, Chen Tianyi's mother was first pushed out of the operating room. Now those who have been pushed out of the operating room are Chen Tianyi, who accepted his mother's liver, and Xiao Yanran, who received Chen Tianyi's liver.

These two little girls who should have nothing to do with each other have now become real "flesh and blood" little sisters because of God's cruel jokes. Looking at the two little girls lying on the flat bed with their heads tilted at the same angle, and even the hairstyles were strikingly similar, even Qian Hongjun, who had seen more scenes, was a little emotionally surprised by the wonder of fate and fate.

The two children looked ...... Can be a long real image.

Dr. Pascal had returned to the operating room and began to adjust and deploy the immunosuppression regimen for the two men when he learned that the surgery was nearing its end. His requirements are very demanding, the ICU and the laboratory department need to perform TDM tests on two people every hour, and the frequency of drug adjustment is accurate to the standard of two hours. Dr. Pascal had only one goal: to do everything possible to reduce the trauma of immunosuppressants to his two children while ensuring the survival of the transplanted liver.

Chen Tianyi's mother was also admitted to the ICU. Of course, her bed was deliberately far apart. This is mainly to ensure that Xiao Yanran's identity is not revealed. However, due to humanitarian considerations, she was able to sleep next door with her daughter.

Chen's mother woke up from anesthesia earlier than the anesthesiologist expected, presumably because she wanted to see her daughter as soon as possible. However, by the time she recovered from anesthesia to semi-consciousness, Chen Tianyi had been lying next to her for almost an hour.

She turned her head sideways to see her daughter, her eyes as if she were looking at a rare treasure in the world. Until the nurse on the side found out about her and came over and gently persuaded her to sleep more.

"How long will it take for her to wake up?" asked Chen Tianyi's mother in a low voice, so she couldn't drink water before the operation in order to prevent suffocation caused by vomiting during anesthesia. For the same reason, you can't drink water for six hours after surgery. Her voice was hoarse and dry, and her throat hurt like a smoking coal.

"About an hour or two. "This nurse in the ICU is also a mother. She understands Chen Tianyi's mother's current situation and worries. But it could be hours before she's fully conscious—it takes time for the anesthetic to metabolize. She thought for a moment and said with a smile, "You sleep first." When she wakes up, I'll call you again, okay?"

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Isabella sat on the edge of Todd's bed, her hands trembling a little. She had been trying to touch Todd's head, but the shocking white bandage, and the deformation of the skull that the bandages could not hide, made her give up again and again.

Todd was admitted to the inpatient unit of the Comprehensive Diagnostic Center. The Nursing Department of the Fourth Hospital has appointed nurse Zhong Yu as the head nurse for the comprehensive diagnosis center, and is also equipped with four nurses, including Xiao Guo. The five nurses are now taking care of Qian Aiwu and Xiao Tao in three shifts, and the manpower has never been more abundant.

Since Takeda has designed a single ward for the inpatient department of the General Diagnostic Center from the beginning of the design, it is of course possible to "upgrade" the single ward to a triple ward if necessary.

In a fairly spacious room, Isabella's figure looks a little ...... Lonely.

Sun Lien stood outside the ward, listening to Isabella's suppressed sobs inside the door, and after a long while, he waited until the voice inside was quiet, and then knocked lightly on the door.

"Please come in. Isabella said in a hoarse voice, and seeing that it was Sun Lien who came in, she quickly wiped the tears on her face, and then showed a somewhat miserable smile and said, "I thought it would be a nurse." ”

"I'll take a look at Todd. Sun Lien said with a smile as he glanced at the top of Todd's head, the words meningitis had begun to fade, and the state of peripheral neuritis and slight pericarditis in the face had completely disappeared. Under the action of three generations of cephalosporin, Todd is recovering quickly. However, to cure Lyme disease completely, antibiotics need to be used continuously for more than 10 days. And Todd is only nine years old, and the preferred drug tetracycline cannot be used. It may take a little time to be completely cured by the third generation of cephalosporin.

Isabella nodded slightly, making way for Sun Lien to do a physical examination. Looking at Sun Lien's quick and skillful examination, she suddenly asked, "Will there be sequelae?"

Sun Lien was silent for a while, "If it was asked by other patients' families, I would definitely not dare to say too much." He pointed to the barely recognizable depression on Todd's head, "Aside from this skull defect, the biggest question now is whether the previous meningitis will have any effect. Apart from these two points, I did not find any other symptoms that could cause sequelae. He thought for a moment and struggled to explain, "Meningitis didn't happen very long, and we found it early enough – it shouldn't be too much of a problem." But this is only my speculation, and the details will not be known until Todd wakes up. ”

Sun Lien's explanation was careful enough, and Isabella nodded, then sighed and stopped talking. Sun Lien was silent for a while, and then said without words, "Dr. Pascal didn't come?"

He ...... He came over. Isabella smiled, "He said he still had a job, so he stayed for a while and left." ”

Sun Lien sighed, but after all, he didn't care much about other people's family affairs, "The job he said was the little girl who needed a liver transplant - her consultation was still contacted by you." ”

Isabella nodded, "I know. She sat down on the sofa next to her and said with a wry smile, "I can understand the urgency of his work, Todd has Lyme disease, and he can't help much......" Saying this, she suddenly remembered something, and hurriedly stood up, "What time is it?"

"Half past four. Sun Lien glanced at his phone, "What's wrong?"

"Penny is out of school, I need to pick it up quickly...... she wanted to pick up her daughter quickly, but she was reluctant to leave Todd, and suddenly felt a little embarrassed.

Sun Lien thought for a moment and proposed, "In this case, I'll ask Dr. Xu to pick up Penny." Xu Yourong was in the office of the Infection Department, waiting for Director Huang to come back and sign. At this point, it's unrealistic to have Isabella or Pascal pick them up, but you can't leave Penny, who is only seven years old, at home. Xu Yourong and Penny have a good relationship, and it is the most suitable choice for her to take a trip.

As for Sun Lien, it was originally the job of the trainees to take the materials and wait for the directors to sign, so it was appropriate for him to do this kind of thing.