"Mining is constantly mentioned in the Chinese Exclusion Act, because mining was very profitable at that time, just like chips now. More than 100 years have passed, but nothing has changed. After Wu Mian finished speaking, he put away the B-ultrasound probe and wiped the couplant on Gelbin Mekatok with a tissue.

"Mr. Gerbin Mekatok has no major problems with his abdominal organs. "Although his liver has a tendency to deposition fat, it doesn't matter. ”

"And then?"

"Go for an MRI. "Mr. Gerbin Mekatok is all negative for autoimmune antibodies, and it is not caused by autoimmune encephalitis.

To rule out these diseases, if the MRI images do not show frontal and temporal lobe atrophy, we can go and have a cup of coffee and wait for the final test results. ”

Owen Rothschild silently pushed the wheelchair and followed behind Wu Mian.

Since he has chosen to come to Huaxia to see Wu Mian for treatment, at least there is still a minimum of trust. Even Wu Mian has repeatedly denied that Gerbin Mekatok is a hybrid of a goblin and a Bigfoot.

One hour later, Wu Mian pointed to the image on the screen in the operation room and said, "Owen, Mr. Gerbin Mecatok's brain shows no signs of atrophy, and his physical condition can be said to be quite good. ”

"Huh?" Owen looked at Wu Mian, waiting for what he had to say next.

"However, MRI images showed symmetrical abnormal signals in the bilateral internal capsule, bilateral internal capsule, hind limbs, bilateral cerebral feet, pons, and cerebellar dentate nucleus. Owen, I'll put it simply, the images suggest something is wrong with the brain, but it's not Alzheimer's disease. ”

“......”

"MRI of the ankle joint showed fusiform enlargement at both Achilles tendons. Wu Mian said, "Here's the problem. ”

"Wu, if I don't understand it wrong, can I say that? Owen Rothschild said cautiously, "Because Gerbin Mercatok has a problem with his foot, which caused him to be in an abnormal mental state?"

When he said this, Owen felt extremely ridiculous in his heart.

Because of the problem with the feet, the brain is not easy to use...... Is this human talk?

But Owen saw Wu Mian and nodded, "Owen, you are really a smart person, what you said is right, this is what I mean." ”

"......" Owen was silent.

"Genetic testing is slow, and we still have a few hours to go. "I suspect that Mr. Gerbin Mecatok has a very rare genetic disease - cerebral tendon xanthelasma. ”

"Tendonsasma?!" Owen didn't understand what it was, was unfamiliar and had never heard of it.

"By the name, you know what the disease is. Cerebral tendon means brain and tendon. ”

“......”

Owen Rothschild had a hard time linking the two organs.

"This is a rare dyslipid disorder. It is generally recessive and is characterized by progressive ataxia, dementia, cataracts, and tendonosasma. ”

"It is usually caused by mutations in CYP27A1 genes, and the incidence is 1 in 1 million worldwide, and the incidence varies in different regions, and we have less domestic reports. ”

"Are you sure?" asked Owen Rothschild.

"Not sure, of course not sure, it's just a guess [new fo]. "We are waiting for the results of genetic testing. ”

"Is it really just a disease, why is the brain and the foot connected?" Owen asked.

"People with tendonosfar are unable to convert cholesterol into bile acids, and cholesterol, another metabolite of cholesterol, cholestanol, is more abundant and accumulates in the body. On the other hand, the deficiency of bile acids, negative feedback, leads to excessive cholesterol production. ”

"Wu, I know that explains why the damn cholesterol is up. "But that doesn't explain the changes in the nervous system, are you kidding? ”

"Owen, how exactly does tendon xanthomasma cause neurotoxicity and damage to the nervous system, there is no definite conclusion. However, it has been hypothesized that large amounts of cholesterol and cholesterol can damage the blood-brain barrier, leading to damage to the central nervous system. Wu Mian said.

"Maybe you're not satisfied with this explanation, so let's wait. Seeing that Owen was silent, Wu Mian continued, "If the genetic test results confirm my guess, even if you don't want to believe it, you can only accept this diagnosis. ”

"Can I trust you?" asked Owen Rothschild as he looked at Wu Mian cautiously and word by word.

"You don't need to believe me, everything is based on objective inspection. "The last piece of the puzzle is still complete, and you can send all the tests to a doctor in any hospital in the world for consultation." ”

"Wu, I trust your judgment. Owen's voice was low, sounding distant, as if it were coming from within the walls.

"Owen, it's science. "Mr. Gerbin Mekatok's physical signs also testify to this. Tendon xanthomasma occurs in 70% of patients, and neurological symptoms appear late and present in a variety of ways, including dementia, behavioural abnormalities, ataxia, pyramidal signs, epilepsy, myelopathy, and peripheral neuropathy. ”

Owen Rothschild was silent.

Wu Mian didn't say anything anymore, uploaded the video data, turned off the machine, and left the MRI room with Aowen to wait for the final test results.

Not surprisingly, the test results confirmed Wu Mian's suspicion that Gerbin Mecatok had a CYP27A1 gene mutation.

"Owen, I'll send all the information to your mailbox. Wu Mian sat in front of the examination table and said very seriously, "I regret to tell you that Mr. Gerbin Mecatok's diagnosis is very clear, it is cerebral tendon xanthelasma. According to your account, when you were at Harvard, the doctor wanted to make a diagnosis, but you and Mecatok ......"

Wu Mian said, sighing.

"Wu, how to treat it?"

"Give it a try, generally speaking, the sooner you treat it, the better the results. Wu Mian said, "The specific effect of neutralizing the chenodeoxycholic acid of Mr. Gerbin Mercatok depends on the sensitivity of his body. However, judging from various sources, I feel that there should be no problem. ”

"Can you wake up?" Owen had a new hope.

If Gerbin Mekatok could wake up, it would be a great thing.

"Probability-wise, it's 85% likely. Wu Mian nodded and said, "Cerebral tendon xanthelasma is a progressive disease, but it is not fatal, and even if it is not treated, you may live to be fifty or sixty years old." However, early detection and early treatment are more conducive to controlling neurological symptoms and making recovery easier. ”

As he spoke, Wu Mian paused.

"It's okay, you have money, as long as you have money, you can solve it!"