Chapter 157: Illegal Additions
The plastic bag brought by Gu Jiahao's father is estimated to cost three cents a piece in the supermarket. It's a big bag. And the scary thing is that this bag is basically full.
"I was afraid of startling the snake, so I just told my sister that Jiahao had a good effect on the medicine she gave. Gu's father handed over the big plastic bag in his hand to Sun Lien, "She said that she was given to me according to the type of medicine she had given to Jiahao before, but I think that Jiahao may still have to admit it - she should have sold me a lot of things." ”
This is a very caring parent. Sun Lien was really taken aback by the pile of things in Gu's father's hand, and then was impressed by the other party's wit, this is indeed the safest way, not only to get those drugs that may have added content, but also not to arouse the suspicion of the other party. Except for the cost of money, there are no other drawbacks.
Just a cursory glance, Sun Lien was sure that there must be at least eight or nine boxes in this bag. Inside the bag was a piece of paper that had been torn off from the nature of the work, on which were handwritten the usage and dosage of various drugs.
"I'll take these things back to see how they're going, and if necessary, maybe send them for poison testing. Sun Lien told Gu's father about his plans for the future, and then said, "We hung a bag of glucose for Xiao Gu, and the infusion will be completed in about half an hour." If his mood is stable, you can take the child back first. ”
Father Gu nodded, then found an empty seat and sat down. The bench with a metal base let out an overwhelmed moan.
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"These are the medicines?" Sun Lien went to Yuan Ping'an with a large bag of medicines. Yuan Ping'an, who was scratching his ears and cheeks to count the illegal addition of drugs in the "Micro Business Diet Pills", flipped through the bag slightly, and suddenly grinned happily, "Hi...... You said it earlier!"
Sun Lien heard a hint of confidence from Yuan Ping'an's words. He was curious, "Do you know this medicine?"
"It's all in the news. Yuan Ping'an showed Sun Lien a page on his computer screen that was published in May this year. "See for yourself. He stretched back and sighed, "If I knew it was this kind of thing, I would have been tired like this." ”
According to the news on the page found by Yuan Ping'an, the Song'an Provincial Administration for Market Regulation, together with industry and commerce and the police, smashed two illegal drug processing sites in Song'an Province. And among them is this capsule diet pill called "Yahe".
"The essence of the contents of this capsule, which is called a pure Chinese medicine preparation, is dyed starch, and the real problem lies in the capsule. Yuan Ping'an introduced to Sun Lien, "In order to escape the crackdown, these counterfeiters added the drugs that need to be added to the capsule shell that actually worked. ”
Sun Lien quickly scanned the news and finally found an introduction to illegal additives - four kinds of sibutramine hydrochloride, phenolphthalein, furosemide and sildenafil were illegally added to the drug.
"......" Sun Lien looked at the four additives on the screen, and after a long time, only two words came out to express his mood at this moment. In fact, he couldn't think of anything else he could say.
Sibutramine hydrochloride is a central nervous system depressant that has been banned from production and marketing for more than a decade. Sibutramine was first used as an antidepressant clinical drug. However, in the process of use, it has been found that the antidepressant effect of this substance on patients is not as obvious as the effect of weight loss. But the drugs that have been developed at a great price can't just be thrown away, so Abbott, the American pharmaceutical company that invented sibutramine, had an idea and repackaged sibutramine into a weight loss drug called "Nomeiting" in 97. Compared with orlistat, which was very hot at the time, sibutramine saved patients from the embarrassment and discomfort of fatty stools. Therefore, once the product was launched, it immediately swept the whole Europe and the United States, and entered China around 2000. As a prescription drug, more than fifteen slimming drugs containing sibutramine are officially available at the same time.
Sibutramine, which acts on the central nervous system, reduces the user's appetite by blocking the reuptake of norepinephrine and serotonin and dopamine, and increases energy expenditure by raising the body's body temperature, thereby reducing body weight. The so-called "no diet, no exercise, lying down to lose weight" is the main selling point of this drug.
Phenolphthalein or fenofoxaline is relatively common and is a prescription laxative. After oral administration, phenolphthalein can form soluble sodium salts in the alkaline environment of the intestine, thereby stimulating the nerve plexus in the intestinal wall, directly acting on the smooth muscle of the intestine and promoting intestinal peristalsis. At the same time, phenolphthalein can also inhibit the absorption of water in the intestine, so that water and electrolytes accumulate in the colon, resulting in a laxative effect.
As for furosemide, Sun Lien is no stranger to this thing. This is a very potent diuretic. Clinically, it is often used in the treatment of patients with acute pulmonary edema, severe edema, cerebral edema, hypercalcemia, etc., especially when other diuretics have not been effective, furosemide is a very powerful and rapid diuretic. After 2~5 minutes of intravenous injection, the patient's urine output will increase, and it can last for 4~6 hours. However, as a loop diuretic acting on the renal tubular epithelium and inhibiting the reabsorption of sodium and potassium ions, furosemide penetrates the blood-brain barrier not as well as mannitol, and because mannitol directly increases the osmotic pressure of cerebrospinal fluid and blood crystals, the effect of furosemide is slightly inferior to mannitol in terms of "shrinking the brain". Therefore, in practical application, Sun Lien and Xu Yourong do not have many opportunities to choose furosemide, and more often than not, mannitol is the first choice - they encounter cerebrovascular accidents more than edema.
As for the last sildenafil, Sun Lien was a little confused, and he said to Yuan Ping'an, "This thing...... It's Viagra, right?"
"What are you talking about so elegantly, are there any lesbians here? Yuan Ping'an smiled, "That's what you think, viagra." ”
"The ...... of these counterfeit drugs What do you do with viagra drugs in diet pills?" Sun Lien suddenly felt inexplicable, could it be that sildenafil also has any unknown weight loss effects?
Yuan Ping'an laughed, "You know the story of Viagra, right?"
"Yes. Sun Lien said inexplicably, "I found side effects when treating pulmonary hypertension." ”
"You're so perfect to miss the point. Yuan Ping'an sighed and prompted, "Not every patient will directly answer this unspeakable side effect. It wasn't until Pfizer discovered that volunteers had been hiding and refusing to return the drug on a large scale that they began investigating the experiment. It was finally determined that sildenafil had this particular side effect. ”
"So......" Sun Lien followed Yuan Ping'an's words and said, "The main purpose of adding sildenafil to diet pills is to increase the patient's dependence on the drug?"
Yuan Ping'an nodded, "After all, what is advertised is to nourish yin and replenish yang and regulate the balance of kidney qi." The effect of sildenafil is so significant, it is estimated that many people will mistakenly think that this so-called pure Chinese medicine preparation is really useful......" he sighed, "What the hell is a pure Chinese medicine preparation? Pure Western medicine is almost the same." If starch is not included in traditional Chinese medicine, then these fake drugs all rely on Western medicine to work. ”
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In the small conference room, Dr. Pascal, Xu Yourong, Zhou Ce, and Yuan Ping'an were all present. Everyone looked at the names of the illegally added drugs listed on the whiteboard, and sighed together for a while, "!"
Even Dr. Pascal let out a "" sound, and then the old man with ginger red hair slapped the table angrily, "This is murder!"
"The specific verdict is a matter for the procuratorate and the court. Sun Lien sighed, although what Lao Pa said in Chinese was true, but in front of him, this kind of thing always made Sun Lien feel particularly humiliated - even if most of these additives were invented by American companies. "What we need to do now is to determine how severe the side effects of the medication are being suffered by this child. ”
"First of all, check the liver function and kidney function. Zhou Ce spoke first, "For children of this age, the organ function is not mature enough, and a large number of illegally added drugs may lead to drug-induced liver damage and acute kidney injury. ”
"At the same time, we have to check his mental condition. Xu Yourong exerted the special carefulness of women at this time, "Maybe you can ask my colleagues from the psychological counseling department to come over and give him a simple assessment?"
Sun Lien's attitude towards this point is still reserved, "The psychology department in our hospital is mainly used as an internal service department, and does not participate in external treatment. They're here to assess the feasibility...... I'll go back and consult Director Zhou. ”
"The most important issue is to report the issue to the relevant authorities as soon as possible. Dr. Pascal said righteously, looking genuinely angry, "This kind of criminal who adds drugs at will must be punished severely!"
"I'll do it. Sun Lien nodded at Lao Pa, "I'll communicate with the patient guy later, and then I'll go directly to Dean Song." ”
Xu Yourong suddenly said, "Do you have another interview later?"
As soon as this remark came out, it immediately attracted the attention of several other people.
"yes......" Sun Lien looked down at his watch, it was half past two in the afternoon—of course, he hadn't eaten lunch yet. "But there should be time. Communicate with the family and then go to Dean Song, there will be no delay in the interview. ”
"I mean, you can talk to those two reporters about it. Xu Yourong reminded, "Of course, the police and the Market Supervision and Administration Bureau will continue to crack down on all kinds of counterfeit drugs, but if you can publicize the role of unlicensed health products to ordinary people, or the effect will be better." ”
Sun Lien thought for a while, nodded and said, "I'll talk to Dean Song." "After all, the reporter of the Economic Daily was invited to cover for himself, and if he didn't report in advance and disrupted Dean Song's plan, I'm afraid he would be stripped of his skin again.
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"Okay. Dean Song agreed to Sun Lien's request without hesitation, "This is a good thing...... she paused, frowned and thought for a while, then waved her hand to Sun Lien and motioned for him to sit down, "Are you okay now?"
"It should be...... No. After all, with the blessing of the god of overtime, Sun Lien really didn't dare to say that he had nothing to do now.
"It's okay. Dean Song picked up the phone in front of him and dialed it out, "It's good for everyone to complete this kind of interview as soon as possible, you can be interviewed in the conference room outside." The phone rang through, and Dean Song said unceremoniously to the person on the other end of the phone, "Xiao Wang, you bring your colleague to my office - the content of your interview needs to be changed." ”