Han Guangyun was completely stunned.

Mr. Wu, who used to be in the mouth of Director Ma, is a celebrity, and it is said that he brought down the privatized county hospital with his bare hands, and the director was sent to prison.

Before the newly renovated building of the county hospital could be used, he was taken into his pocket and turned into the fifth hospital of the medical university. Moreover, the people of the five hospitals of the Medical University do not use it at all, and directly show the signboards of Cambridge and Concord.

But this is the Second Hospital of the Medical University, the medical department of the Second Hospital of the Medical University, why is he so arrogant!

Although he thought so in his heart, Director Han really wanted to point to his nose and ask him why he was so arrogant. But my finger hurt so badly that I almost broke it just now. was taught once, and he was already cowardly in his heart.

"Do you know what a filistim is?" Wu Mian asked almost as he lay in his chair.

"......" Han Guangyun was speechless for a while, he really didn't know what a filgrastim was.

Not to mention that he is a layman, most doctors in the clinic don't know about it.

It is also a recombinant human granulocyte colony-stimulating factor, which has many trade names, and filgrastim is a special brand name for colony-stimulating factor produced by Amgen in the United States.

"You don't know anything here, so grab our nurse's hair and ask her to apologize, Director Han, is it debatable whether you said it's debatable. Wu Mian said leisurely.

Director Ma was stunned for a moment, and what flashed in his heart was that Dean Xue had talked about the tragic ending of the Zhang brothers in the county hospital.

The nurse named Li Qiong has become our nurse in Mr. Wu's mouth, and this matter has become a dispute between the second and fifth hospitals of the medical university.

And with Mr. Wu's means, the Ministry of Foreign Affairs and the Ministry of Commerce directly came forward to decorate the hospital...... If you want to get a department-level cadre in the second hospital of the medical university, it is not too simple.

"Teacher Wu......" Ma Xiude trotted, "rolled" to Wu Mian's side, and whispered.

After only one name was called, Matthew stopped talking. Everything was silent, and he believed that Wu Mian could understand.

"Dean Ma. Wu Mian sat on the chair, turned around for half a circle, looked at Ma Xiude, and said very seriously, "You also have something wrong with this matter." ”

"Yes, yes. Matthew didn't argue at all, he nodded again and again.

Mr. Wu is usually reasonable, but if you are really unreasonable, don't argue with him.

Seeing Ma Xiude like that, Wu Mian couldn't help laughing.

The room full of frost melted in an instant.

"Dean Ma, it's not me talking about you. Wu Mian gently tapped the arm of the chair with the fingers of his right hand and said, "In 1985, there was the first undergraduate nursing major in the country. In 1994 and '95, the university began to expand its enrollment, and the number of undergraduate nurses finally increased. ”

"What did Concord do at that time?"

"Go directly to the school, as long as you are willing to come to Concord, the written test and skills are directly compiled. ”

"Others don't know, say the doctor's mouth, the nurse's leg. You old medical director, can you still not know this?"

"What the hell are you going to say!" Han Guangyun was quite resistant in his heart, and said fiercely.

Wu Mian glanced at him and smiled slightly, "Dean Ma takes care of the overall situation, this is to take care of you, why are you still hitting the muzzle of the gun." ”

Han Guangyun glared at Wu Mian, full of anger.

"Let me ask you, did you consult the whole hospital after the accident?" Wu Mian looked at Han Guangyun and said.

"It's already clear, it's ......"

Wu Mian stood up as soon as he "Teng", Han Guangyun was like a frightened rabbit, quickly filled, jumped directly to the corner, and shouted like a little girl who had met a villain, "What are you going to do!"

"After the accident, you know how to dump the pot, and you don't even invite the whole hospital to consult?" Wu Mian was also taken aback by Han Guangyun's actions, and said with a smile.

Han Guangyun was afraid that Wu Mian would make a move, so he didn't dare to stiffen his mouth.

"In abdominal trauma, the incidence of spleen injury is as high as 40-50%, and spleen injury is more common in trauma. Non-traumatic splenic rupture accounts for only 1 percent of splenic injuries and is quite rare in clinical practice. Wu Mian sat down slowly and said very casually, "The patient doesn't understand, and you don't understand? You are the chief of medical affairs, and you are the director of the medical department, and you are here to resolve disputes, not to create contradictions!"

"Oh, I'm sorry, you really don't understand. Wu Mian didn't bother to explain to him, and smiled disdainfully, "The preliminary consideration is that it is a spontaneous spontaneous spleen rupture caused by filgrastim, and it has nothing to do with nursing work." ”

The director of the respiratory department, who was standing at the door, heard Wu Mian say this, walked in cautiously and asked, "Teacher Wu, hello." ”

"Huh. Wu Mian didn't bother to pay attention to him, and laughed halfway.

"What do you mean by non-spontaneous splenic rupture?" asked the director of the respiratory department, looking at Wu Mian in confusion.

"Nontraumatic splenic rupture is being understood, and in 1958 Orloff and Pesk proposed four criteria for diagnosis: no history of trauma, no adhesions outside the lesion suggesting a previous injury, no other disease involving the spleen, and specimens that are normal both microscopically and generally. ”

"In 1958, the concept of standards was proposed, and you probably didn't learn it in school. Wu Mian looked at the director of the respiratory department and asked.

"Mr. Wu, I do know about non-traumatic splenic rupture, but the drugs we use are all commonly used in clinical practice, and the patients themselves ......."

Wu Mian directly interrupted him and said, "Figrastim is a recombinant human granulocyte colony-stimulating factor, which is commonly used for hematopoietic stem cell mobilization, chronic severe neutropenia, and bone marrow suppression after chemotherapy. ”

"In pre-marketing clinical studies, it has also been observed to cause mild splenomegaly in most healthy subjects, but this change is reversible, often resolves within a few weeks, and the degree of splenomegaly is also related to the dose and duration of application. ”

"At that time, my teacher, Dr. Anthony's teacher, suggested that filgrastim could lead to spontaneous spontaneous splenic rupture, but the US FDA still approved the clinical approval of this drug. ”

"Over the years, we've been looking for similar medical records. A total of 23 similar cases have been found in Europe and the United States, which is not too many in China, and this is the first case. ”

The middle-aged man from Amgen had a sad face, but he didn't dare to say a word.

The director of the respiratory department of the Second Hospital of the Medical University was stunned, there are problems with the instructions of imported medicines?

"Five years ago, Dr. Anthony suggested that filgrastim add a sentence to the instructions. Wu Mian continued, "Splenic rupture has also been reported in the literature with the application of recombinant human granulocyte colony-stimulating factor in healthy subjects, at doses of 10 and 20 μgkg. Although splenic rupture due to recombinant human granulocyte colony-stimulating factor is rare, and there is no evidence of features that increase the risk of patients, clinicians need to be aware of this possibility when administering medications. ”

Wu Mian only explained a few words to the director of the Department of Respiratory Medicine of the Second Hospital of the Medical University, and then looked at the manager of Amgen, "You solve this problem first, and then talk about the manual." ”

"Teacher Wu, raise your hand. ”

"You're not good enough to talk to me about this. Wu Mian smiled and said.