Chapter 80 Clinical Trials

The person who asked was an old man with a straight face, wearing a pair of sandals with exposed toes on his feet and short-sleeved gray trousers, four or five forehead lines hanging on his forehead, his eyes were sharp, and then he saw Zheng Jianguo looking at himself and turned his head to look at the side, but he didn't expect Qin Lianzheng to squeeze in with sweat: "Jianguo, this is President Guan Qingshan of the People's Hospital——"

"Vice, the positive one is almost hot~"

The old man looked at Zheng Jianguo's chin with a pair of eyes, his gaze swept over the operating table in the laboratory, nodded and said, "Yes, it's not worse than my side-"

"This is a door-to-door kick in the gym?"

Zheng Jianguo turned his head to look at Qin Lianzheng, who gave an inexplicable look to him, and he knew what the origin of this person was, so he immediately got up and said: "Since Helicobacter was just discovered, its pathogenicity is still being studied, but the teacher Ye Minde considered that since it was a campylobacter species, he set a treatment plan to use gentamicin or amoxicillin and metronidazole at the same time and then observe it——"

"I've heard about this. ”

The old man raised his chin and said, looked at Qin Lianzheng next to him and said, "Since this kind of patient with Helicobacter has not found a stomach ulcer——"

"According to the information I have, the age of this group of people is generally relatively young, 80 percent is under the age of 25, and 60 percent is under the age of 40—"

Zheng Jianguo glanced at the notebook in his hand and said that he had been here for a month, but not only to do Helicobacter culture, Helicobium had results as early as the third day of culture, and most of the rest of the time was analyzing the pathology of stomach disease, plus he had a lot of experience in the problems caused by Helicobacter in his memory. You've made this statistic—"

"There are still plenty of cases. ”

Zheng Jianguo looked at the old man who didn't take the notebook, and couldn't help but have a good feeling in his heart, the day before yesterday, there was a deputy director of the cancer hospital who wanted to see it, but Ye Minde, who had not left at the time, directly refused.

"Well, I can see that the cancer hospital has been busy this month-"

Guan Qingshan's voice was a lot quieter after he finished speaking, at this time, medical care has not been industrialized, and the treatment of major hospitals can be said to be similar, everyone gets their salaries according to their professional titles, and the salary is less than two yuan, in terms of its welfare alone, if it is not a regional specialized hospital, such as a tumor hospital here, its treatment is similar to that of teachers here.

However, due to the relatively narrow departments that need to be built in specialized hospitals, the professional experience of its doctors is relatively large, so even if the doctors in the general hospital recommend it, they will recommend it to the patient to the specialized hospital for treatment.

In addition to the benefits, that is, the department's business ability can attract the attention of an old doctor like Guan Qingshan, and when he saw Zheng Jianguo's clear eyes and clear speech, he took out the hand behind his back, looked at him and smiled: "The author of this article, Zheng Jianguo of Qi Provincial Medical College, is you?"

Guan Qingshan was holding a magazine that had been opened to the middle of the page, and the exposed part was the medical dynamics on the head, and in the inconspicuous corner of the lower left corner of the page, the short message called Helicobacter in Gastric Ulcer was written concisely and concisely with a few familiar paragraphs, and at the end of the text fell Zheng Jianguo of Qi Provincial Medical College with eight oblique Song style No. 10 characters.

Zheng Jianguo was stunned, and then he wanted to reach out to get it with a look of ecstasy, but Guan Qingshan handed it over when he raised his eyes: "Take it, I'll give it to you." ”

"Then what's so embarrassing, it's useless, I'll just take a look-"

Subconsciously took it, Zheng Jianguo said from beginning to end again, counting the punctuation marks, there were only more than 600 words and less than 700 words, and Guan Qingshan's voice came from his ears: "Hehe, I'm relieved if you say that, take it, there will be trouble for you in the future." ”

"Huh?"

Zheng Jianguo raised his head quickly, but he didn't expect Guan Qingshan to look at him with a kind smile: "You asked Director Qiu to say hello, but he didn't even show his face, I thought you went home from vacation to rest, but I didn't expect to run to the side of the tumor, until I read this short message yesterday and remembered it again, it seems that you are almost busy here——"

"Ah, you-"

Zheng Jianguo was stunned again, and then his eyes flashed to the request made by Wei Jianran at that time, but he didn't expect that Deputy Director Qiu really did what he said, and he thought that people might not agree, and then thought that if it wasn't for this Vice Dean Guan running over to talk about it, it would be difficult to offend people and not know how to offend them, thinking of this, he wanted to speak, Guan Qingshan's hand was raised: "But the conditions here are good, you go to my side, I don't have a chance to touch the edge of the microscope——"

"I would also like to thank Director Fei for his great support and the care of the hospital leaders. ”

After this month of waiting, Zheng Jianguo knows that not to mention the scarcity of ultra-high magnification electron microscopes in these years, there is no way if people don't lend it to you in order to avoid damage to use, of course, he can come over because Ye Minde himself can reach this level.

Thinking about the fee that Ye Minde asked himself to pay after the successful discovery of Helicobacter in dyeing, he could feel that doing research at this time was not only a matter of money, but also a relationship, otherwise it was really possible to carry a pig's head and not find the temple gate: "It's almost busy here, and all that remains is to enter the treatment feedback during the follow-up period, and then compare it with the original case after summarization, and you can get the first-hand treatment effect." ”

"Is the culture of bacteria successful?"

Guan Qingshan curiously looked at the incubator opened by Lin Yongmei next to him and asked, the latter turned his head to look at Zheng Jianguo, and he said: "It has been successfully cultivated, at that time, the teacher designed different cultivation programs at the same time in order to speed up the progress, among them, according to the non-selective standard, there was growth when the cultivation reached 78 hours, which was nearly 30 hours more than the standard 48 hours——"

Zheng Jianguo is lucky, compared with the original memory of Professor Warren, that is, the discoverer who could only discover Helicobacter in 1981 three years later, he has an extremely professional expert mentor in microbiology, who helped him overcome the problem of isolation and cultivation that originally had to rely on continuous exploration and experimentation after discovery, shortening the original Warren from 4 years to one week, and further consolidating the results of this Helicobacter discovery.

Of course, this is the second step of the Long March, Guan Qingshan, who was slightly browbrowed, nodded slowly and said, "Then the next step is a biological experiment?"

"The next step is my plan for clinical trials. ”

Zheng Jianguo said that he saw Guan Qingshan's brows twisted into a pimple, and he also knew that his decision was a bit risky, according to the normal research progress in China at this time, the next step should be to find some rabbits, dogs and cats for infection testing.

Of course, the ideal is to find primates that are closest to humans, such as monkeys, but considering that it is a pipe dream, it is directly thrown behind and chooses the choice that Professor Warren once chose - clinical trials.

But the four words of clinical trial just sound enough to make people creepy, but fortunately, Zheng Jianguo has persuaded his mentor Ye Minde, and immediately said with the other party's face down: "I have tested myself in the past two days, and the tissue biopsy from the oral cavity to the gastroscopy has not found this Helicobacter. ”

"You want to experiment with yourself?"

Guan Qingshan finally changed color, when he heard about clinical trials before, his first thought was that this bastard who didn't know the height of the sky was going to abandon the moral bottom line of researchers, and deliberately infect people with this new and unknown bacteria in order to meet his research purposes, but he didn't expect that he was going to test himself!

"Are you crazy?"

Guan Qingshan had this thought circling in his mind, looked at Zheng Jianguo, who was full of calmness, and found that not only his expression was calm, but also Qin Lianzheng next to him didn't seem to be anything unusual, so he finally erased this thought and said, "Tell me what you think?"

"That's what I'm here for. ”

Zheng Jianguo smiled, he didn't expect Guan Qingshan's attitude to be almost the same as Ye Minde, and immediately said: "Up to now, there have been many patients infected with Helicobacter, after the treatment of gentamicin or amoxicillin combined with metronidazole, the Helicobacter in the mouth and stomach has been removed.

Now the first batch of patients who have been detected have had a follow-up visit, and I plan to wait until a few days after these patients return to the clinic and the results still do not detect this Helibacterium, it means that the treatment is working-"

"Then you can test yourself and treat it with effective drugs if you get infected—"

Zheng Jianguo's next plan flashed in his mind, Guan Qingshan looked at the unreal young cheek in front of him with a solemn expression, he wanted to say what if the treatment failed, people's physique is not exactly the same, and some drugs can work on others-

However, thinking that Zheng Jianguo's actions were to prove the pathogenicity of this newly discovered bacteria, this spirit is admirable, and the purpose of Shennong to taste a hundred herbs to test the poison is still for people's health, and his spirit of dedication cannot be exaggerated, and then thinking of this young graduate student in the Republic, Guan Qingshan said: "Professor Ye agreed?"