After hearing this, everyone was shocked, and if Academician Chen said that it was not optimistic, then it must be a rare case.

I saw Chen Chengquan continue: "A month ago, the Department of Hepatobiliary and Pancreatic Surgery of our hospital received a 9-year-old boy Xiaoqiang and a 13-year-old boy Xiao Ale. They each had two rare inherited metabolic diseases. One is that Xiaoqiang, who suffers from hypermethioninemia, needs to take special foods for a long time, and the results of the previous examination showed that the head MRI showed that the brain had white matter damage, and if it developed further, mental retardation and neurological damage may occur. ”

However, Ah Le, who suffers from both OTCD and HHH syndrome, has recurrent hepatic encephalopathy, and even with a severely restricted protein diet, he has already experienced severe neurological damage such as brain atrophy. ”

"For a disease like theirs, for the two children, the liver transplant is the key, and it is also imminent! But at present, neither of them has waited for the liver source!" Chen Chengquan sighed.

"Is it that the condition of the two children has suddenly deteriorated now?" Liao Jie guessed.

"Yes! Xiaoqiang began to show signs of nervous system damage. Ah Le's brain atrophy began to be severe, and the nervous system began to be damaged. It is best to get a liver transplant within half a month...... But now the news from the liver source center has not yet found a matching liver source, let alone waiting......," Chen Chengquan said in a deep voice.

Ruan Bin frowned after hearing this.

As a result, the situation of these two children is really critical. Wait any longer, and both of them will become complete idiots.

As for why the two children have metabolic genetic diseases, why do they need to have their livers replaced?

That's because the liver plays an important role in the body's metabolic process. Hereditary metabolic diseases can manifest as simple abnormal liver function indicators, or they can manifest as abnormal function of multiple organs including the liver, and some diseases have normal liver function indicators and extrahepatic organ damage due to liver metabolic enzyme defects.

The vast majority of inherited metabolic diseases are protein dysfunction caused by single-gene abnormalities, and the protein involved can be a single metabolic enzyme in the liver, or a structural protein, receptor, hormone, or transporter expressed in multiple organs, including the liver.

Therefore, this hereditary metabolic disease can be completely cured by surgical liver transplantation!

Otherwise......

GG！

"At present, the two children have the same blood type, similar body size, and little difference in liver morphology, and it is theoretically possible to achieve the perfection of liver function by swapping part of their livers for cross-assisted domino liver transplantation. This is also in the same direction as the topic of [swapping part of the patient's liver] that we are currently studying!" Chen Chengquan continued with a serious face: "Here are all the examination data and current conditions of the two patients, you all convey it and take a look, and see if you can say what you think!"

"Double Domino donor liver cross-assisted liver transplantation?" Ruan Bin had heard of this new type of liver transplantation.

It seems to have been invented 4 years ago.

Double domino donor liver cross-assisted liver transplantation has good experience and effectiveness in the treatment of patients with familial amyloidosis.

What is familial amyloidosis? It is a clinical syndrome in which amyloid is deposited between the cells of various organs in the body due to a variety of reasons, resulting in the gradual failure of the affected organs.

Therefore, this kind of patient also needs liver transplant treatment!

The recipients of the double domino liver are patients with familial amyloidosis, the first domino donor is Wilson's disease, and the second domino recipient is ornithine carbamoyltransferase deficiency (OTCD).

Children with this kind of domino donor liver are all treated with living donor liver transplantation (left lateral lobe donor liver) by general resection of diseased liver for double domino donor liver transplantation, including partial resection of the diseased liver of the domino liver transplant recipient, as well as donor liver resection and backstage outflow tract reconstruction, and vascular reconstruction, and resection of the residual liver of the domino liver transplant recipient...... Wait a minute.

In other words, this kind of familial liver transplantation can exchange part of the liver.

This is also what Chen Chengquan just proposed, can we consider letting these two children learn from this exchange method, and then combine it with the specific condition to create a new surgical method?

The main reason is that these two children have the same blood type, similar body size, and little difference in liver morphology, so they have this condition to try to create a partial liver swap!

The crowd took the various examination materials of the two patients for detailed viewing and evaluation.

"It's difficult! I've never had any experience in this area!" Liao Jie said with a dark face.

It's too difficult.

If it succeeds, it will be the first of its kind in the world!

"Ding-dong...... System Temporary Missions: Blockbuster Missions, Solve Puzzles, Blockbusters, Complete Tasks and Reward 3 Lottery Chances!"

"Hey, you're on a mission?" Ruan Bin was overjoyed.

In that case, he doesn't want to keep a low profile.

"System!"

[System points]: 148,600

[Split Liver Transplantation]: World-class+

That's right, Ruan Bin is ready to upgrade this liver transplant to the innovative level and see if you can solve the problem he is currently experiencing.

There are many types of liver transplantation, the most traditional classical liver transplantation, which refers to replacing the diseased liver with a new liver, and piggyback liver transplantation. With the innovation of technology, there are also new surgeries such as living-donor partial liver transplantation, split liver transplantation, and domino liver transplantation.

But in Ruan Bin's eyes, liver transplants are different except for a few parts, and most of them are the same, such as the reconstruction of the ducts in the liver.

This step is required for every liver transplant.

Then the problem comes, Ruan Bin thinks that when he upgrades this transplant to the innovative level, that is, the highest level, then in the end, he may be able to make this split liver transplant go the same way, and at the same time can do the skills required by the above surgeries!

After all, it is already the pinnacle of liver transplant surgery, and it will definitely be able to bypass, assimilate, and innovate new things!

Only if you know all the liver transplants can you innovate new procedures!

If it really can't be done then, then you have to upgrade the domino liver transplant.

"Level up!"

"Ding-dong...... After deducting 21,000 points, [split liver transplantation]: innovative!"

Rumble!

Sure enough, Ruan Bin had countless surgical experiences in his mind and tens of thousands of various types of liver transplants.

It's not just split-liver migration!

He felt like he would have a living-donor partial liver transplant, a domino liver transplant, the most traditional liver transplant in the first place......

Just when everyone was thinking and meditating, Ruan Bin said: "I think that although the two metabolic diseases of the two patients can cause nervous system damage, I analyzed their examination and imaging results, and found that the damage sites are in different pathways of the liver, and there is no crossover, the two have the same blood type, the body size is similar, and the liver shape is not much different, I think I can let a patient swap the left half of the liver to complete the liver transplantation!"