The results of C01C, a benzothiazinone compound, were published in the Journal of the American Chemical Society.

Shen Qi's chemistry group has published two papers in the Journal of the American Chemical Society, which have attracted attention in the industry.

At this stage, C01C can only be regarded as a new compound, and it cannot be called a drug commodity.

At least after the animal experiments have been done and the expected results have been obtained, it is more valuable for C01C to patent the localization of glycogen synthase kinase-3β inhibitors.

The animal experiments were followed up by Obeqi Pharmaceuticals, and the patent for C01C was sold to Obeqi Pharmaceuticals.

It is not so easy to develop an original drug, even if it passes animal experiments, there are still several clinical trials.

The first phase of clinical trial is mainly to test whether the new drug is toxic or otherwise harmful to normal healthy people, and this stage is usually completed with the assistance of dozens of healthy volunteers, and the cost can be controlled within 10 million RMB.

Phase II clinical trial mainly tests the efficacy of new drugs, and this stage requires the cooperation of hundreds of patients, and the cost will soar to more than 100 million RMB.

After that, there is a phase III to test the optimal dose of the new drug, and a clinical phase IV to investigate the efficacy and adverse reactions of the drug under the conditions of widespread use. The number of patients selected at this stage may exceed 10,000 people, and the cost will reach hundreds of millions of RMB.

Before an original drug made money, hundreds of millions of funds were smashed into it.

Moreover, even if a large sum of money is spent, it is possible to fail.

From animal experiments to several phases of clinical trials, if there is a problem in any link, and the compound is verified to be ineffective and harmful, the entire development project has to be overturned, and the development team must continuously improve the properties of the compound in all aspects to meet the relevant standards of the listed country.

If Shen Qi wants to sell the patent of C01C, someone has to dare to buy it.

It is not expensive to buy a patent for a new compound, but the cost of subsequent research and development and testing is too expensive.

Lao Shen's Obeqi Pharmaceutical is fearless, this pharmaceutical factory was originally bought by Lao Shen for Shen Qi to play.

It's just that if it is broken, the family property that Lao Shen has saved in the past 20 years of business will never return, and Shen Qi and Ou Ye's 100 million, and Shen Qi's mother-in-law's 100 million will also be lost.

"Any attempt to gain profit, to gain honor, or to satisfy a personal desire is risky. For example, Xiao Wu, you follow me to study for a Ph.D., and in the first two years, you don't do a project but become a tutor, which is a risk. Shen Qi said to his doctoral student in mathematics, Wu Shangfeng.

The publication of the C01C paper brought Shen Qi more than 400,000 points to the top students, and counting the previous balance, Shen Qi had 520,000 points to get the top student points.

A more effective way to resist risks is to improve physical fitness, Shen Qi took out 400,000 points of Xueba points to upgrade sports to level 8.

My aunt set up a stall to sell pancakes and fruits, and she got up early and worked hard to lose more than 10,000 yuan a year. Wu Shangfeng said indifferently.

"It's not easy to do any business. Shen Qi expressed sympathy for Wu Shangfeng's aunt, and asked, "How is the pilot class going?"

"It's the end of the period, the business is going great, ouch, it's time, I have to go. Wu Shangfeng picked up the information and hurriedly wanted to leave.

"Let's go and see it too. Shen Qi walked with Wu Shangfeng.

The two came to a large classroom in the teaching building, Wu Shangfeng entered through the front door, and Shen Qi secretly observed outside the back door.

The students in the classroom are all first-year students in the School of Mathematics, and after this final exam, they will enter their sophomore year.

Shen Qi applied for 12 hours of undergraduate teaching tasks this semester, and 4 semester hours were each allocated for advanced algebra, mathematics and solution. The remaining credit hours are completed by the instructor.

After the end of the teaching in the classroom, Wu Shangfeng regularly organizes tutorial classes to answer the doubts of the freshman students in terms of high generation, counting, and solving.

Wu Shangfeng is relatively comprehensive, and he can handle the three basic mathematics courses alone.

This can be done by a single PhD student in charge of a multi-course tutorial for undergraduate students.

At the graduate level, as the courses become more and more professional, only an all-round mathematician like Shen Qi can tutor graduate students in mathematics in all directions.

Wu Shangfeng faced the younger students of undergraduates, and he was comfortable with tutoring.

"Next, I'm going to analyze a representative problem of advanced algebra. Wu Shangfeng switched PPT, and a high-generation problem was displayed on the screen, matrix operation.

The final exam is coming soon, and the freshman students are listening carefully to Wu Shangfeng's lecture, and they know that Wu Shangfeng is the only mathematics doctoral student recruited by Shen Qi in China.

Mr. Wu was devoted, and the students were also engaged, and the university classroom seemed to have the atmosphere of a senior high school classroom.

Shen Qi's idea is to set up a pilot tutorial class from the first year of the School of Mathematics.

Wu Shangfeng's two-year career as a tutor is over, and this class of freshmen has just finished their junior year.

Shen Qi will wait and see what changes will happen to the senior students who have received the tutorial.

Shen Qi, who was secretly observing outside the back door, found that the effect of the tutorial class was still good.

First-year students in the School of Mathematics are enthusiastic about studying, after all, the final exam is approaching, and in this special period, students must have enthusiasm for learning.

The students were listening to the lecture and taking notes, except for a girl in the last row, who was sleeping on her desk.

Shen Qi's cat waist jumped into the back row of the classroom from the back door without making a sound.

Sitting gently next to the sleeping girl, Shen Qi patted the girl's shoulder and whispered, "Classmate, wake up." ”

The girl didn't move, she slept too soundly.

Shen Qi picked up his fist and slapped the girl, which woke the girl up.

The girl's arm was still on the desk, she turned her head to look at Shen Qi, and said unhappily, "What are you doing...... Hey, is that you? Professor Shen?"

Shen Qi said: "This classmate, if you want to sleep, you might as well go back to the dormitory to sleep." ”

The girl looked at the screen in front of her, and turned to Shen Qi and said, "The topic that this Teacher Wu said is too simple, I fell asleep after listening to it." ”

So natural, so reasonable, Shen Qi couldn't help but look at the girl twice, the woman's forehead bone is narrow, the cheekbones are high, the nose bone is thin and narrow, the eye sockets are deep, and the facial horizontal line is more prominent.

This kind of woman with a three-dimensional layered physiognomy looks awesome on the surface, but in fact it is not so awesome.

Shen Qi smiled, took the girl's notebook and pen in his hand, wrote the topic on the notebook, and returned the notebook to the girl.

The girl was surprised at first, but quickly regained her calm demeanor, she stared intently at Shen Qi's math problem, and fell into deep thought.