365 These years are worth it!

When Li Zheng and Chang Keqing were preparing the next set of samples, Shi Yang and Mo Nian had already breathed a sigh of relief and completed the "rotational" CT.

Although it is only a short three minutes, the 3.73G data has been transmitted to the storage array, but at this time it is only some simple high-precision images, and it still needs the help of software and algorithms to analyze them into three-dimensional structural diagrams.

Behind Shi Yang, Liu Tao looked at the small molecule on the screen like a lump of black briquettes, and couldn't help but lean over and raise his glasses.

"Not bad...... It was so clear the first time......"

"I'm also ......shocked," Shi Yang also wiped his sweat, "The difficulty of playing cryo-EM is mainly in the preparation of sample crystals, as long as the sample purity and parameters are in place, anyone can read a beautiful structure...... But this time we ...... It seems like it's just grinding?"

Mo Nian nodded and said, "To be exact, I casually ground the progesterone that was kept in the chemical hospital." ”

"Wait......" Shen Yiyun next to him was startled, "Didn't you carefully prepare this sample?"

Mo Nian spread his hands: "I took it from the consumables casually." ”

"This ...... Why?" Shen Yiyun scratched his head and shouted, "Our group wants to make a qualified sample, but it takes ten days and half a month, and it would be good to make a bunch of crystals and have one that can be used." ”

"It's different, it's fundamentally different. According to biological thinking, you think that cryo-EM is inherently designed to analyze some rare and complex macromolecules and protein structures, and in order to remove interference and analyze the specified information, the demand for samples is harsh. Instead, we just want to see simple small molecule structures, which can be found everywhere and are extremely pure. ”

"Shouldn't the gold standard for analyzing the structure of small molecules be X-ray single crystal diffraction?" Shen Yiyun eagerly compared, "It is also even more difficult to make qualified crystals." ”

"That's why we need an electron microscope!" Shi Yang excitedly grabbed Shen Yiyun's shoulders, "It's uplifted, sister! We have upgraded the chemical microscope this time, from X-ray to CT." ”

"Yes...... This ......" Shen Yiyun even ignored the fact that Shi Yang didn't wash his hands, and just said blankly, "It's too simple...... 3 minutes?"

At this time, Li Zheng, who had prepared the next sample, had already walked over.

"It should be 10 minutes. After Li Zheng looked at the screen, he turned back to Liu Tao and said, "Next, we will use the Adaboost algorithm to screen out suitable images for three-dimensional construction." ”

"Hiccup...... Oh. Liu Tao hiccuped in panic, "Come on, follow me to the workstation outside." ”

"I, I, I!" Shi Yang jumped up, nodded at Li Zheng with a gleam in his eyes, and then pushed Liu Tao out of the laboratory without saying a word.

Li Zheng then sat down in front of the operating table.

"This group does 140° diffraction, rotates 0.5° per second, and has a resolution of 0.8?. Li Zheng sighed, moved his neck and rushed to Shen Yiyun who was sluggish next to him, "I've worked hard to guide." ”

At the same time, the leader of the most crotch-pulling group, Lin Moming, and the duo started the preparation of the next set of samples, but in fact, the eyes of the two people were always locked on the electron microscope body.

Tu Yikou: I have to find a way to dismantle one......

Lin Moming: I have to find a way to buy one......

Just as their third group of samples was placed in the electron microscope, the sound of smashing glass was suddenly heard.

Shi Yang was outside with his teeth and claws, waving wildly.

"it...... Wouldn't it......" Shen Yiyun was startled, and subconsciously glanced at the wall clock, "13 minutes?"

Li Zheng just blew the hair on his forehead and got up and said, "You keep an eye on it, I'll go out." ”

"I'm going to see it too!!"

"Next time, next time. ”

Li Zheng trotted to the door, and as soon as he opened the door, Shi Yang's shouts poured into the inner room like a thousand miles.

"Gan Niniang's Li Zheng!!This has become !!"

As soon as they heard this, all the people in the inner room couldn't bear it anymore, put down the experiment at hand and chased it out.

Only the leader, who stopped in place, secretly approached the electron microscope body while they went out to look at the image.

In the outhouse, everyone gathered in front of the workstation screen and squeezed the dazed Liu Tao to the very back.

"It's too fast, it's too simple!!" Shi Yang pointed to the screen and howled, "X-ray may not be a good job for half a month, and the electron microscope will be done in 10 minutes!!"

"Ah......" Shen Yiyun stared at the structural diagram on the screen that looked like a mole tunnel, took off his glasses and rubbed them vigorously, and looked at them again, "Although it's a little sloppy...... But this structure ...... It's progesterone, yes......"

In the rear, Lin Moming jumped a lot before she could barely see the picture, but she still didn't dare to be too happy, panting and asked, "This, this...... It's that simple? Why didn't anyone find out? We were the first?!"

"For the time being...... But...... It's really too simple. Although Li Zheng was very satisfied with the structure analyzed for the first time, he still frowned, and after thinking about it, he finally took out his mobile phone and said to Shi Yang at the same time, "This picture will be sent to Zhou Chenghuan immediately, and I will apply to catch up with the schedule." ”

"OK! I'll just send me an email with the parameters. Shi Yang's little fat hand moved up at the speed of light, moving back and forth between the three screens and three keyboards.

……

Forty minutes later.

When Zhou Yi rushed into the laboratory, he saw a sluggish Liu Tao, a Shen Yiyun who was thinking about life, a Li Zheng who was processing data, and Chang Keqing who was filling out the experiment report.

Everyone didn't care about greeting Zhou Yi, and Zhou Yi didn't care about greeting everyone, so he just rushed straight to the screen, grabbed the mouse, and quickly read the analysis images of the three experiments.

After a while, Zhou Yi turned his head and almost shook off his eyes: "Liu Tao, did you watch this process with your own eyes?"

Liu Tao was stunned for a while before he remembered to nod: "Yes...... Right...... It's simpler and clearer than 100% of other experiments......"

Zhou Yi immediately fell into a tremor, tried to straighten his glasses several times but failed, and finally simply threw away the glasses and picked up Li Zheng.

"Oh my God!!" Zhou Yi grabbed Li Zheng's head, his eyes were bloody, and he wanted to stick the door of his head on it, "How the hell did you think you could do this!!"

"Spirit...... The inspiration is in place......" Li Zheng didn't dare to look at Zhou Yi directly, for fear of becoming a ring, "This time still bothers you...... The main reason is that this experiment is too simple, even if we don't do it, it is only a matter of time before others make it, if you want to calculate the results of the Institute of Evolution, I hope you can find a way to buy us some more time for laboratory operations. ”

"Fight!!We must fight!!" Zhou Yi put down Li Zheng, picked up his glasses, stared at Mo Nian, Shi Yang and others who were still manipulating in the glass window, pointed to it and said, "Immediately come up with a simple experimental report, explain the matter very badly, just paste the picture, I will take this to pat the dean's face, and give you a 7X24-hour electron microscope treatment!!"

As soon as his voice fell, Chang Keqing in front of the workstation next to him had already raised his head: "It has been sent to your mailbox, if you need a printed version, I will print it immediately." ”

Zhou Yi turned his head again, and the glasses he had just put on flew out again: "It's only been two hours!!"

"About 1 hour and 10 minutes, to be exact. Li Zheng leaned over to help Zhou Yi pick up his glasses, "Ah...... Shattered ......"

"Damn, that's troublesome. Zhou Yi took the glasses, simply pierced the broken lens, and then hurriedly put them on, and pulled Li Zheng up again, "Go!

After that, he turned to glare at Liu Tao again: "Xiao Liu, you work hard, today they said that you don't want to leave until the end." ”

“…… Oh. ”

……

The smoothness of the experiment far exceeded everyone's imagination, and until 9:40, when Li Zheng sat in the living room of Zhang Shilei, the dean of the institute, was still a little magical.

In the scientific research circle, although problems such as learning valves have been criticized, there is one thing that is absolutely superior to all other fields.

That's the leader, he really understands technology.

At least in the hardcore science and engineering fields, the people in power must have sufficient academic achievements, and there will never be a situation where laymen lead insiders.

Although Zhang Shilei does not have much hair, his appearance is not good, and he is entangled in daily management affairs, his academic ability is still as high as 2482, and his academic qualifications are more than 10,000 yuan higher than Zhou Yi.

Generally speaking, once Li Zheng sees this kind of data, he knows that things are stable.

Sure enough, Zhang Shilei only asked a few questions, and made a phone call with Liu Tao, so he escaped into the study and started a series of communications.

According to Zhou Yi's explanation, the current cryo-EM is mainly used by Hu Zengwu's organic photovoltaic team, and if all the recent use rights are arranged to Li Zheng's group, Hu Zengwu must be explained and appeased.

After all, Hu Zengwu is a discipline leader in a major direction, if he doesn't nod, even Zhang Shilei will not be able to snatch the experimental time.

Although Zhou Yi was determined, when he thought of Hu Zengwu, he inevitably had some concerns.

"Oops...... I knew you were training at that time, so I shouldn't mess with him......" Zhou Yi took off his glasses and muttered while wiping the empty frames, "Who knew that I would bump into ...... at this time"

"yes, who knows. Li Zheng shook his head and sighed, "It's okay, Dean Zhou, if Professor Hu doesn't agree, we will work overtime at night, from seven o'clock in the evening to seven o'clock in the morning." ”

"Let's not say that you can't bear it, then I'm afraid the laboratory operation and maintenance personnel are going to revolt......"

"Hmm...... We have a team member who can pay them overtime. ”

"Hah...... Haha......"

"She's serious, and she's bringing money into the group to solve this unforeseen problem. ”

"This also brings capital into the group?" Zhou Yi leaned on the sofa and shook his head and sighed, "But this can be regarded as a vision, if you knew in advance that you could have this kind of result, it would be so fast...... I'm afraid that half the circle of people is asking you to bring money into the group. ”

As he was talking, Zhang Shilei walked out of the study with a surprised face.

Li Zheng and Zhou Yi hurriedly got up, judging from his face, the result of this negotiation did not seem to be very good.

"Old Hu, old Hu......" Zhang Shilei kept shaking his head and walked to the coffee table, "What's the matter...... Just say yes?!"

Li Zheng and Zhou Yi looked shocked at the same time.

Zhang Shilei couldn't figure it out, and said to Li Zheng: "Professor Hu originally didn't agree, but when he heard your name, he relented and said that you were a piece of material." ”

"???" Zhou Yi was shocked, and his glasses went out of control again, "This is the Hu Zengwu I know?"

Zhang Shilei then asked Li Zheng: "Do you have a friendship?"

"Hmm...... I used to go to Mr. Hu's laboratory to help. Li Zheng scratched his head and smiled, "Teacher Hu can do it, he is also this material." ”

Zhang Shilei was stunned for a moment, glanced at Zhou Yi, and the two laughed at the same time.

"Then I will definitely convey it to Lao Hu. ”

"It seems that Xiao Li's must be very important. ”

After sitting down again, the dean's wife also brought tea.

Li Zheng wanted to rush back to the laboratory and let the two deans have a detailed chat, but he was forced to stay.

People of every age, every position, will always have different reactions and thoughts when they see things.

For the two deans, the data of the two hours in front of them has proved that this experiment is bound to have great results.

After getting Hu Zengwu, compared to Li Zheng's race against time, they had already tacitly thought of the next step.

After a look, Zhang Shilei put down the experimental report in his hand, looked at Li Zheng and solemnly nodded to the table: "Li Zheng, according to my judgment and that of Dean Zhou, this is worth a CNS." ”

When Li Zheng heard this, he didn't have too many expressions.

That's worth it!

After all, it is the cutting-edge breakthrough content in the system.

The so-called CNS is not a telecom operator, but three scientific journals.

Cell, Nature, and Science.

For most researchers, it is almost everyone's greatest ideal to be able to publish a CNS paper in addition to the unrealistic Nobel Prize.

In other words, a person who has sent CNS, wherever he goes, deserves to be called a big guy.

Taking this as the standard of strength, of course, is a bit pedantic or admiring the foreign.

Unfortunately, this is still the most reliable standard.

Not only reliable, but also valuable.

Almost any university in China will receive a bonus ranging from 50 to 1 million yuan as long as it successfully publishes a CNS paper.

Another regret is that many scientific researchers of the older generation, due to the limited conditions and resources of the year, although they have made a lot of research and contributions, have not had the opportunity to win this honor.

On the contrary, many young researchers have become famous at a young age due to the investment of large resources and the entry of cutting-edge tools such as "cryo-EM".

If you don't say anything, even Zhou Yi and Zhang Shilei in front of you have not appeared on CNS.

On the contrary, it was Hu Zengwu who gambled a lot in the field of organic photovoltaics and caught up with the times.

"To be famous is to ...... early" Zhou Yi looked at Li Zheng and became uncontrollably jealous, "But you kid, this is too fucking early......"

As Li Zheng, he is actually very restrained, and he only started to rectify this until he fully studied in college, or because of the system's mercy on people with disabilities.

"Or ......" Li Zheng was indeed a little unbearable, so he asked, "Dean Zhou will be the first author, right?"

"Ah, no, no, no, that's not what it meant. Zhou Yi hurriedly shrank and waved his hand, "I barely gave any guidance, it would be nice to be able to hang on the head of our chemical courtyard." ”

"Okay, Li Zheng. Zhang Shilei also raised his hand and pressed it, "We don't come to this institute, whoever does the research is whoever, especially Dean Zhou, he has always been committed to giving young talents room to grow, you may not realize that Dean Zhou has been sprinkling his efforts on competitions and enrollment for decades, just to welcome the emergence of seedlings like you." ”

Zhang Shilei finished speaking, and raised the teacup high: "I see how young people say that now...... Zhou Yi, the eternal god of Huajing. ”

"Forever dripping gods!" Li Zheng was said to be energetic, and then raised the teacup high, "Without Teacher Zhou, there would be no such experiment, Jinghuajing will always be dripping gods!"

"Don't ...... Don't be so ......" Zhou Yi barely raised his glass, his eyes not feeling wet, "But...... Dean Zhang is really someone who knows me...... Seeing that you and Shi Yang can grow up...... All these years, it's worth it!

"Cheers!"

After clinking glasses, Zhang Shilei and Zhou Yi discussed the next step.

Yes, it is necessary to have a strategy to send CNS......

Li Zheng also came into contact with these things for the first time.

First of all, as CNS reviewers, they are also human beings, not all-rounders.

In particular, the reviewers of the first review are not big guys, they are only responsible for preliminarily judging the value of the paper, and the biggest basis is the author of the paper.

If it is a little-known author, then you have to scan it roughly, judge whether it is parallel or genuine by feeling, and even in many cases, the preliminary reviewer has to Google the author first when he gets the paper.

Although this judgment is based on a rough one, it is easy to use, and most of the people who are not famous in Google are indeed lucky to send parallel papers.

This is the case, the so-called tutor resources, academic authority, not to mention anything else, just hanging your name on your paper is already heavyweight support.

In order to increase the success rate of CNS, it stands to reason that a famous boss should be named.

But Li Zheng himself only accepted Zhou Yi's name.

It's a pity that Zhou Yi's international reputation is not outstanding, and more of his experience is invested in education.

Therefore, even with Zhou Yi's endorsement, the effect is still limited.

So, you can only use the second strategy -

Greet.

The so-called greeting is that a big guy with a head and face calls the reviewer and tells him that there is a good paper and pay attention to it.

This is another manifestation of the mentor resource, the authority of the learning valve.

Today's Institute of Chemical Sciences is the most famous in the world and is at the forefront.

It's Hu Zengwu again.

There is no way, betting in the right direction is to have everything.

Therefore, what Zhang Shilei means is that Li Zheng has tried to tie up Hu Zengwu as much as possible recently, and of course the hospital will do work, but it is not as effective as his own.

Regarding this, Li Zheng is inevitably a little repulsed.

"Otherwise, let's send it in China......," Li Zheng muttered, "Where to send it, it's not good, and it's also excellent to improve the level of domestic academic journals." ”

"No, no, no. Zhou Yi shook his head again and again, "I said it, you have to become famous as soon as possible, as long as you become famous first, everything else will be easy to do." I'll tell you, send a CNS out, you can ask for any resources in school, don't even say you want to ask for it, many people will be eager to give it to you. For the convenience of your future research, let's take a CNS first. ”

"Yes, and ......" Zhang Shilei was not ambiguous, and said directly, "This is not just your business, our chemical institute has not been out of the CNS this year, so it should be regarded as helping Zhou Yi, helping me, and helping the chemical institute to do this." Taking a step back, there is also a bonus of 500,000. ”

"Since both teachers are so persistent, then I try my best. Li Zheng sighed, "But I still won't go out of my way to stammer Teacher Hu, and he doesn't necessarily like this." ”

"Then let's take it one step at a time. Zhang Shilei said, patted his legs and got up and said, "In this case, you should go and get the results out as soon as possible, Zhou Yi and I will help you review the paper when we have time to ensure that its form meets the taste of CNS." ”

Li Zheng stood up and said goodbye: "Thank you, Dean Zhang, since this is the purpose, we will also try to adapt to the format and taste of CNS." ”

After a few polite words, Zhou Yi said goodbye to Li Zheng.

Until he walked out of the building, Zhou Yi was still unsatisfied.

Standing in the yard and looking at the moonlight, I didn't get in the car for a long time.

"Dean Zhou?"

"It's okay, I'll watch it for a while. Zhou Yi raised his head and said, "Settle down, I need to settle down......"

"This ...... This time ...... thing," Li Zheng raised his head and looked at the moon with him, "You should really be in charge...... I don't mind at all, you deserve it, even if you don't consider the experimental resources you have brought up, just look at the hard work you've put into young students for so many years, it's worth it. ”

"Shut up. ”

“……”

"Haha, I'm scared, don't say that in the future. ”

Zhou Yi turned his head as he said and gave a wang wang smile.

"There are so many deans and professors, not all of them are people like me, and some of them want to win talents. ”

"I know you're ambitious, and you can even say things like improving the level of domestic academic journals, but you have to be famous first. ”

"Only when you are famous, your talent is your talent. ”

"Only when you are famous will you scare off those who covet you. ”

"Only when you are famous, you don't need to make compromises, you don't need to seek resource support from people like me, and you can still do the research you want. ”

"For me, a CNS article is nothing more than when I go to the competition and dig up seedlings, those who don't look down on my scientific research level will have to bow their heads and surrender, and I don't care about these at all. ”

"But for you, a CNS will make it the bright moon in the night sky in front of you. ”

"What Yingpei, what chemical institute, what tutor, all have to think that you are accurate. ”

"For me, it's the icing on the cake, and for you, it's like a tiger's wings. ”

"So, it has to be yours. ”

Li Zheng listened unusually restlessly.

I was about to shout out.

No beep!

Ring, big ring!

"Well, don't say anything. Zhou Yi shook his hand with a smile, "Don't feel indebted to me, one day, when others mention you, I can tell him with a smile, Li Zheng, this kid was dug up by me, didn't I make a lot of money?"

"Earn big, Dean Zhou, we've all made a lot of money!"

"Huh. Zhou Yi smiled, "But I do have a little bit of selfishness, it's not a request, it's just a selfish idea, whether you are satisfied or not doesn't affect the future." ”

"But it doesn't hurt to say that. ”

"If it's possible, let Shi Yang's kid do more, it's best to be the second author. Zhou Yi shook his head and said, "The research progress on my side has always been limited...... I always think I'm delaying him......"

"Where is it, Shi Yang is the second author. ”

"That's good. Zhou Yi said and opened the car door, "Public and private, we have all made it clear, and the rest ...... Let's do it!"

What else can Li Zheng say?

Staring into the car.

"it!"