At the beginning of the 21st century, more than a dozen academicians jointly proposed to upgrade BEPC to BEPC-II to better carry out China's high-energy physics research.

In 2009, BEPC-II was upgraded and put into operation.

However, in the field of high-energy physics, the upgrading of hardware has always failed to catch up with the advanced ideas of physicists.

Playing SLR ruined a lifetime, and playing high-energy physics ruined three generations.

No matter how rich Shenhao is burning money in the field of high-energy physics, it won't be long before he has to go back to before liberation.

The great ambition of a high-energy physicist must be achieved by national power.

BEPC-II is under the supervision of the Academy of Sciences, and Dean Shen Qi and Dean Cao must first consult Dean Bai for their ideas on BEPC-III.

Dean Bai has been on a business trip these days, so Shen Qi and Dean Cao came over to step on it first.

Director Hu was quite surprised when he heard Shen Qi's idea of upgrading.

"The construction of the China Super Collider is about to start, is it necessary for us to upgrade the BEPC-II?" Director Hu meant that the BEPC-II should be used together first, and it would be good to wait until the China Super Collider is completed.

China's Super Collider is a higher-energy existence than the European Large Collider, with a total investment budget of 100 billion yuan, located in North China, the conceptual design has been completed, and the construction period is expected to be ten years.

Of course, Shen Qi and Dean Cao knew about the China Super Collider project, and Shen Qi said: "Some people say that the China Super Collider will start construction this year, some people say that it will start next year, and some people say that it is a waste of money to build this thing." Even if construction of the Chinese Super Collider begins this year, it will be ten years before it can be operational. ”

Dean Cao: "I am very supportive of the China Super Collider project, and I participated in the initial research work of this project, but Lao Hu, wait another ten years, we will all be old." I think the upgrade of BEPC is necessary, and BEPC will continue to be our main force in ten years. Ten years from now, BEPC will still be available for teaching. ”

Lao Hu was noncommittal: "This matter is too big, let's talk about it when Dean Bai comes back." ”

A few days later, Dean Bai returned from a business trip.

Dean Bai is an expert in hardware, and he calculated that upgrading BEPC-II to BEPC-III requires at least 3 billion yuan, and the upgrade cycle will not be less than 3 years, and many accessories need to be redeveloped.

"3 billion, 3 years, is this necessary Shen Qi?" asked Dean Bai.

Shen Qi opened his laptop and pulled up a file: "I have made a preliminary calculation in the past few days, about 1.5 billion is enough, and the upgrade can be completed within a year and a half." Dean Bai, in fact, you and I both know that the China Super Collider project will definitely be done, but it is unknown when the construction will be completed. For a long time, our research in high-energy physics in China still had to rely on BEPC. In my opinion, the upgrade of BEPC is necessary. ”

Dean Bai carefully examined Shen Qi's calculation plan, and after a long time, Dean Bai said: "Shen Qi, Shen Qi, you are really heartbroken for our Academy of Sciences. If you don't want the next dean, you can do it. ”

Dean Bai smiled. Shen Qi waved his hand and smiled.

In the end, Dean Bai's resolution was that the upgrade plan for the capital's electron-positron collider project needed to be reported to the state, and the state would decide whether to invest manpower, material and financial resources to upgrade.

The work of reporting to the state was promoted by the Academy of Sciences, and Shen Qi released the improved physics skeleton, which clearly defined the four hidden ones and the physics of tomorrow.

When the country was researching the BEPC-III project, Shen Qi received the latest news from Obeqi Pharmaceutical.

Regarding C01C-2, the plasma half-life in rats, dogs and macaques is 1.7~4.9h, and the oral bioavailability is 68%~100%.

In these experimental animals, systematic clearance of C01C-2 is primarily achieved by the kidneys in the form of intact maternal drugs, but also by bile excretion and physiological metabolism.

In other words, the animal experiments on C01C-2 have been successfully completed and can enter the clinical trial stage.

The positioning of C01C-2 is now clear, it is a chemical drug for the treatment of diabetes.

Phase I clinical trials are mainly to study the tolerance of new drugs and propose preliminary, safe and effective dosing regimens to guide the next phase of clinical trials.

The number of test samples in phase I clinical trials is generally 10~30 cases, and the test subjects are mainly healthy volunteers, and some patients can also be selected.

Most pharmaceutical companies entrust qualified institutions to do clinical trials, and OBEQI Pharmaceutical is also preparing to do so, entrusting an institution in Nangang City to do the phase I clinical trial of C01C-2.

The above information was conveyed to Shen Qi by Lao Shen.

Of course Shen Qi has no opinion, do it.

When Shen Nuofei turned two years old, C01C-2 entered the phase I clinical trial.

Shen Qi is concerned about the clinical trial performance of C01C-2 and the approval of BEPC-III.

Ou Ye's physical condition is in a stable and unstable state, the medicine has not been broken, but it is still the same, and the root cannot be cured.

For couples like Shen Qi and Ou Ye who have status and savings, one child is slightly less, and it is best to have a few children.

The couple already have a daughter, and if they have a son, they will have both children and daughters, and it will be perfect.

Shen Qi wanted to have another son, and Ou Ye also wanted to.

Ou Ye was twenty-eight years old when she gave birth to Shen Nuofei, and she is 30 years old this year, which is not too old.

Under normal circumstances, it is not a big problem for a 30-year-old woman to have another child.

But Shen Qi and Ou Ye are neat, and Erbao just can't be rectified.

What should I do if I can't fix it?

Then make it hard.

But the problem is that Shen Qi and Ou Ye have been working hard for a long time, but there is still no good news.

On the contrary, Ou Ye's body was a little unbearable.

"Slow down, slow down. Shen Qi was sweating, he had done his best.

"My body is still dragging its feet. Ou Yexian's guilt said, "Your C01C-2 is for diabetes." ”

Shen Qi sighed: "Hey, theoretically speaking, glycogen synthase kinase-3β is a target related to a variety of diseases, including diabetes, Alzheimer's disease, cancer, immune diseases, etc., I first wanted to make some efforts in immune diseases, but wife, you also know that the discipline of chemistry is ever-changing, and I will make C01C-2 a treatment drug for diabetes." Maybe I didn't have enough knowledge in chemistry and biology to achieve accurate strikes. I'm sorry for you, wife. ”

"It doesn't matter, if you can cure diabetes, it's also a great merit. After all, Ou Ye is also a scientific research worker, and she can distinguish the difference between everyone and Xiaojia.

Shen Qi couldn't help it, even if I could heal the whole world, I couldn't save my wife, it would be too painful.

"Wife, don't worry, in the process of researching C01C-2, I have also learned some new things, and there will be C01C-3 and C01C-4 in the future, until you are cured. ”