The phone is dialed.

"Mom, I'm Nophi. ”

"Well, Nofi is so good. ”

"Mom, are you okay in the hospital?"

"Don't worry, baby Nofi, mommy is fine. ”

"Mom, is the hospital signal good?"

"It's good, I ......."

Shen Qi suddenly interjected: "Child, mother, let's talk about the point, Professor Qu is going to you soon." ”

"Oh, yes, Nophi, Mommy is doing a routine check-up, and there's nothing wrong with that. You have to listen to your dad at home, you know?"

"Uh-huh!"

"Nofi, let Dad take you to buy a new red dress, red shoes, and red hair card, and then you put them on, and ask Dad to take a picture and send it to Mom, okay?"

"Okay. ”

"Baby, awesome! Mommy loves you. ”

"Nofi loves her mother, too. ”

“Mua~”

“Mua~”

"Bye-bye Nofi. ”

"Bye-bye, Mom. ”

The mother and daughter ended the call, and Shen Qi said to Nofi: "Your mother is fine, she is fine." ”

"Well, I hope mom comes home soon. Shen Nuofei felt a little relieved, during the call just now, she felt that her mother seemed to be quite normal.

Cuckoo~

Hungry voices rang out.

Nofi patted his stomach and said, "Eh, I'm so hungry." ”

Shen Qi touched her daughter's head: "Do you want to finish lunch in kindergarten, or do you want to go out to eat with your father?"

Nofinunu mouthed: "Only children do multiple-choice questions." ”

"Could it be that you're a big kid and want to eat two lunches in a row?"

"I like to eat the most. ”

"Okay, okay, eat!"

The daughter is the lover of her father's previous life, and she coaxes her daughter to eat, but it seems that her father still needs to take action in person.

Yanda People's Hospital.

Ouye's actual situation is not as great as she presented on the phone.

After taking triazaoctene for two weeks, Ou Ye experienced a loss of appetite and drowsiness.

These are all normal clinical drug reactions, and Ouye forced himself to stick to it.

Before he was admitted to the hospital, Ou Ye ate very little three meals a day.

Admitted to the hospital for a clinical trial, Ouye ate less.

If a person eats less, his complexion and mental outlook are certainly not much better.

Ou Ye's height of 1.6 meters is close to 1.7 meters, and now she weighs only more than 70 pounds.

And Shen Nuofei, a little Lori who is less than 1.2 meters tall, weighs more than 50 pounds.

One can imagine how thin Ou Ye is.

She didn't want her daughter to see her disgraced appearance.

Whether it is a mother or a father, she always wants to show her most handsome, beautiful, spirited, and proud appearance in front of her children.

Ouye turned on the phone's camera function, and the camera was pointed at her face.

The yellow muscles on the screen are thin, and the black straight black silk that she is most proud of is more than one meter long, but it is withered and lusterless.

"I'm so ugly...... Ou Ye muttered, she couldn't stand it anymore, so she turned off the camera.

A woman has lost her beauty, she has lost her vitality, she has lost her health.

Will her husband remain faithful to this marriage?

To make a more vulgar assumption, if a frail woman has not done that little thing between husband and wife with her energetic, tiger-wolf husband for a long time, will the husband cheat physically or mentally?

Maybe, yes......

It is said that there is no filial son in front of the bed for a long time.

Can there be a loyal husband in front of the bed for such a long time?

Maybe, yes......

The ellipsis stands for uncertainty.

Ouye wasn't sure, she could only think on the bright side.

Medicine.

Take medicine.

I have to get better as soon as possible.

For the sake of the children, for the sake of my husband, for the sake of this family, and for myself.

Medicine.

Take more medicine.

Miracles are made vigorously.

However, you can't take the medicine indiscriminately, and you don't take a lot of it.

In phase I clinical trials, tolerability trials have strict dosage criteria.

The lowest dose is usually calculated from the NOAEL of the most suitable animal, and then divided by the safety factor to obtain the human MRSD.

Several groups were set up between the minimum starting dose and the maximum dose, and at least five dose groups were the lowest, lower, medium, higher, and highest dose groups. Only one dose of the trial is allowed per subject.

Ou Ye was placed in the lowest dose test group, which was fully considered by the study physician and Shen Qi.

It is a medicine that is three parts poisonous. The more the medicine is taken and the greater the dose taken, the stronger the toxicological effect.

Phase I clinical trials are mainly to test the safety of new drugs and the dose that subjects can tolerate.

Regardless of how much you eat or how little you eat, there are usually adverse reactions.

Once the severe adverse reactions such as death, life-threatening, organ failure, disability, and teratogenicity appear, the new drug will be clicked off.

Loss of appetite, vomiting, and drowsiness were identified as acceptable adverse reactions by the team of study physicians in this clinical trial.

Ou Ye had an acceptable adverse reaction, which was a little uncomfortable, but it was also a normal situation.

At this time, the door of the ward opened, and the responsible physician, Professor Qu, walked in.

Ou Ye, who was lying on the bed, struggled to get up, and Professor Qu hurriedly stopped: "Professor Ou, you just lie down." ”

After that, Professor Qu adjusted the tilt angle of the back of the hospital bed so that Ou Ye could communicate with him in a comfortable posture as much as possible.

"Excuse me, Professor Qu. Ou Ye barely managed to squeeze out a smile, which looked almost like he didn't smile.

"No trouble, no trouble, you are a patient, I am a doctor, and I should serve you. What's more, Professor Shen is my friend, and you are also my friend, so it is also appropriate to serve your friends. Professor Qu pulled the tablet in his hand and said, "You have been taking the drug for two weeks, and no serious adverse reactions have been found, and the core indicators of hemoglobin concentration, hematocrit, protein saturation, and CRP are also normal. In other words, you take this dose of this new drug, and it seems safe at the moment. ”

"Professor Ou, you are in the lowest dose group, and the lowest dose group will do the tolerance test first, and in another week, the tolerance test of your lowest dose group will be completed. If the lowest dose group is verified to be safe at that time, then Professor Ou can go home to recuperate first, and then you can come to our hospital again after a while for pharmacokinetics/efficacy trials. Actually, it's not a big deal, as your research physician and your friend, I'm just here to talk to you and see if you need anything?"

Professor Wat communicated with Ouye in a more relaxed tone, which made Ouye feel more secure.

"Professor Qu, can I increase the dose when I do pharmacokinetic/efficacy testing?" Ou Ye put forward her needs.

Professor Qu shook his head and said, "No, no, we can't do this, we have to strictly abide by the clinical trial standards, one is for the good of patients, and the other is for better scientific research." Xiaoou, I understand your eagerness to recover, but let me tell you again, the main purpose of phase I clinical trials is to study the safety of new drugs, and of course, efficacy tests will also be done. Throughout the history of clinical medicine, it is very rare for patients who have been completely cured in phase I clinical trials of new drugs, or patients whose disease has been in great remission. Even if you take the highest dose of a new drug, it will be difficult to achieve the results you desire. Unless a miracle happens. ”

"Miracle...... Miracle ......" Ou Ye whispered, she remembered a line, if you don't have a dream, what is the difference between being a man and a salted fish.