Sleeping pills are one of the most common and best-selling drugs in modern society, and not being able to sleep is almost one of the most painful things in life.

The increasing pressure of modern social life, this electromagnetic and noise pollution, the popularization of smart phones and the rich nightlife, the human biological clock is chaotic step by step, and difficulty falling asleep and insomnia have become very serious problems in the current society.

Although Fan Xian is not an expert in this area, as a doctor, she often prescribes some sleeping drugs to patients in many cases, after all, the pain after surgery is not easy for everyone to bear. Thanks to her intelligence and memory, which are far beyond ordinary people, she has a good understanding of the sleeping pills that are currently mainly used in clinical practice, as well as the sleeping pills that have been used on a large scale.

At present, the mainstream sleeping drugs on the market have gone through three generations of development, and there are still problems of one kind or another. The first generation is drugs such as barbiturates, among which hydroxyzine is more suitable for patients with autonomic dysfunction; chloral hydrate is widely used in drug clinical trials and rapid hypnosis when non-collaborators undergo some special examinations because of the less interaction between drugs; phenobarbital can be used for alternative and decreasing treatment of benzodiazepines and other hypnotic drugs, and can also be used for diseases such as sleepwalking, sleep terrors and nightmares in children, or used to antagonize the central excitatory adverse reactions of drugs such as ephedrine, amphetamines, and aminophylline.

The second generation mainly refers to benzodiazepine-sedative-hypnotic drugs. This class of drugs is one of the most commonly used sedative, hypnotic and anxiolytic drugs in clinical practice. Among them, diazepam (diazepam) used to be the most frequently used drug in clinical practice. Chlordiazepoxide (Chlordiazepoxide) was the first to be synthesized in this class, and the psychoactivity of this drug was discovered in the animal laboratory of the pharmacology department of the pharmaceutical company in Laroche, Switzerland, and soon after, a second drug, diazepam, was introduced.

Among the drugs in this class, methylquinone, meprolam, chlordiazeptem, diazepam, and sulpiride are developed in the early stage, and **, midazolam, flurazepam, nitrazepam, estazolam, alprazolam, lorazepam, etc., are developed in the later stage. These sleeping pills are characterized by a high therapeutic index, low toxicity to internal organs, and safe use. So far, it is still a commonly used medication for insomnia.

Benzodiazepines can rapidly induce patients to fall asleep, reduce the number of nocturnal awakenings, prolong sleep care and improve sleep quality, but also change the usual sleep pattern, so that light sleep is prolonged, the duration of REM sleepy eyes is shortened, the time of first REM sleep is delayed, and dreaming is reduced or disappears.

Benzodiazepines have their own characteristics. Such as: fast absorption, fast onset, no accumulation, no sequelae, is an ideal hypnotic drug, but the disadvantage is that the half-life is short, easy to produce morning insomnia and daytime anxiety after medication. Flurazepam: It has a long half-life, and morning insomnia and daytime anxiety rarely occur, but it is easy to accumulate because its main metabolites are active, and the half-life of the active metabolites is as long as 47~100h.

The third-generation sedative-hypnotic drugs are well absorbed orally, reaching the peak of blood concentration in half an hour, and the drug metabolism and excretion are fast, with a half-life of 3~6 hours, and are metabolized by the kidneys. This class of drugs has a high therapeutic index and high safety. It basically does not change the normal physiological sleep structure, and does not produce tolerance and dependence. Adverse reactions are related to the individual sensitivity of patients, and occasionally include drowsiness, dizziness, bitter mouth, nausea and forgetfulness. Such safer hypnotics include zolpidem, zaleplon, zopiclone, etc.

Although it has developed for three generations, and there are still new sleeping drugs coming out, the main problems of sleeping pills are still concentrated in two aspects: the first is the decreasing effect, with the long-term use of a drug either need to increase the dose, or to replace the new drug to sleep well; the second is the accumulation in the body, when the dose is not well controlled, it may affect the working state of the next day, and the residual drugs in the body are not easy to eliminate.

And now Du Qifang from the black seedlings, a poison that can make people sleep quietly in the past, the sleeping drug is directly acting on the central nervous system to relax the body, slow down the thinking, and make people naturally enter a state of sleep through concentrated attention. Of course, the dose of this drug can cause people to sleep for so long that the respiratory system loses its function, and then dies of suffocation.

However, Du Qifang modified it at Lu Huan's suggestion and added several Chinese herbal medicines, which will not have any effect on the efficacy and the human body at low concentrations, but when the concentration is high to a certain extent, it will interfere with the original effect of this drug and turn it into a sweet drink, eliminating the possibility of suicide or murder with this drug......

After the test of Du Qifang and Lu Huan, this drug has been used in mice for a long time and has not had any observable effects on the sleep structure and physiological function of mice.

Fan Xian carefully considered all the indicators provided by Du Qifang so far, and muttered: "A drug with great potential, if it can really be achieved without side effects, then only this one drug is enough for your pharmaceutical company to build a brand among the general public, plus the application value of thermostat in the field of professional medicine, Lu Huan, you are going to make a fortune." ”

Lu Huan rubbed his chin and said a little scoundrelly: "That's, you don't look at the business I'm investing in now, which one is at a loss?"

The two women despised him for his brazenness, but after thinking about it, they reluctantly found that what Lu Huan said was still the truth, he messed around all day long, and there was really no loss-making business, on the contrary, he made more money than ordinary people and made a lot of money.

"Does your pharmaceutical company have a name?" Fan Xian asked suddenly, and the three of them talked for a long time, but until now they didn't even know the name of the company they discussed.

"Future. ”

"Uh, isn't this the same name as your restaurant?" Fan Xian was stunned.

"This is natural!" Lu Huan said as a matter of course, "It's not so simple to think of a good name, and scattered business is also a kind of strength, our nutrition restaurant has a strong biomedical research and development ability, which can increase his persuasiveness, this is the brand price, I hope that in the future, these two words will be the most eye-catching signboard in all fields." ”

Fan Xian looked at the young doctor in surprise, unable to imagine that in a short period of time, he already had such a long-term vision, and the little doctor who had just walked into the city was already like two people.

His shining wisdom and grand strategic planning have been more long-term than the vision of most businessmen in China, and in everyone's experience is still focused on short-term profits, he is already thinking about establishing a century-old brand for Huaxia, just like Coca-Cola, just like Apple, just like Google......

Seeing Fan Xian's surprised gaze, Du Qifang's face flashed with pride.

The ups and downs of his growth are best known only to her who has always been by his side and watched him go from a lazy doctor who sleeps in meetings to a rising star in Ducheng.

......

......

Two days later, Cui Musha gave Lu Huan three trademark alternatives that he asked the industry's top advertising companies to design, and finally Lu Huan chose the first one recommended to him by Cui Musha.

Seeing that he chose this plan, Cui Musha smiled from the bottom of his heart: "Brother Lu, your ambition is really great. ”

"Ambition...... That's not a bad word either. Lu Huan laughed and shook his head, "Actually, it's not that complicated, I just think that whether it's ideal or bragging, it's not like someone else's, it's interesting." ”

That is what Du Fu said, the words are not shocking, you guy, you are indeed developing in this direction. Du Qifang saw Lu Huan's choice and accurately summarized Lu Huan's thoughts.

The trademark chosen by Lu Huan is mainly a green leaf and a blue earth, the tip of the leaf hangs down at the location of Huaxia on the earth, and the green color spreads out from the position of contact, radiating the whole of China, the whole of Asia, and the whole earth......

The green leaves are a metaphor for the fact that all the sources of Lu Huan are traditional Chinese medicine, and the earth represents Lu Huan's ideal of the whole world, not just limited to Ducheng or Huaxia.

The design of the whole logo is very spiritual, with a sense of unfinished flow, and it also represents the two words of the company's name: the future, everything is constantly moving forward.

If this trademark abstracts the color, it is an orange with a leaf, which is simple and easy to remember, and after adding the color and explanation, it also fully satisfies the representative meaning of the Future Group in Lu Huan's heart.

I believe that as long as the group develops to a certain scale, this trademark and the future will become a huge force to change the world......

After discussing the trademark with Cui Musha, there are still many details of the problem, Lu Huan has also set the opening time of the restaurant in the future, and it will be officially opened on September 30, the day before the Golden Week.

After that, Lu Huan was invited by Wang Nianlian to the headquarters building of the Ducheng Branch of Rongchuang Group.

Wang Niangarlic personally greeted Lu Huan out, and it was immediately the opening of Rongchuang's largest project in Ducheng, for this project Rongchuang invested too much, and when the whole real estate was getting lower and lower after the country's continuous regulation and control, if there was any failure in this project, Rongchuang could not afford to lose, as a listed company, the failure of such a major project would make the entire enterprise suffer a heavy blow.

Especially when Yu Liuzhi and Zai Hai died one after another, the power of the Wang family in the terrestrial world of Ducheng no longer has enough control, and Wang Nianlian's father can be regarded as a dangerous move, and the enemy of Lu Huan has been included in their blueprint.

"Brother Lu, I'll give you a gift. ”

Wang Niangarlic had already been detoxified, shook hands with Lu Huan gracefully, and stuffed a small thing into Lu Huan's hand.

Lu Huan was stunned. (..) (The strongest imperial doctor...) /11/11018/)--

( Strongest Imperial Doctor )