As she grew older, Nofi seemed to have developed her own system of three views. Shen Qi didn't seem to discipline Nofi during this time, but he paid attention to Nofi's every bit all the time.

"I think the subjective wishes of children should be respected. ”

"That's so, but if Nofi studies Chinese in the future, writes after graduation, and becomes a writer, can you accept it?" Shen Qi asked.

Ou Ye said as a matter of course: "Of course it is acceptable, writers are also families, no different from mathematicians and physicists." ”

Shen Qi shook his head and said: "You can accept it, but I can't, write a dead end, and Nofi must not embark on this dead end." ”

Ou Ye also shook his head: "I don't dare to agree." ”

Shen Qi explained: "I don't look down on writers or other forms of literary and artistic workers, and I don't object to Nofi learning writing, literature, history, music, and other literary and artistic specialties. I mean, Nofi can have one skill or a lot of skills, but she's definitely going to have a science-related career in the future, even if she studies economics and becomes an economist, I can accept that. ”

Ou Ye: "All in all, your arrangement is that Nofi's future career must be linked to mathematics, physics and chemistry, even if it is not directly linked, it must be indirectly linked, such as economics, which is closely related to mathematics?"

Shen Qi nodded very clearly: "Say something from your heart, yes." ”

Ou Ye gently stroked his abdomen: "Then what are you going to arrange for this in my stomach?"

Shen Qi's arrangement was clear: "This cub, it's best to learn management." ”

Ou Ye poked Shen Qi's chest: "One cub takes over your class in academic majors, and the other cub takes over the Shen Zhishan Foundation in management, you are a typical imperial thought." ”

Shen Qi also poked Ou Ye's chest: "There are some things that have to be passed on, right? If we have a third child, we can cultivate this child in literature and art." ”

Ou Ye said categorically: "I will give birth to two at most, and you can do the rest yourself." Didn't you master the in vitro cultivation technology, you can cultivate it yourself, and clone 10,000 little Shen Qi. ”

Shen Qi smiled: "Forget it, in terms of inheritance, I still prefer the traditional way of operation." ”

In the laboratory, Shen Qi is doing the most advanced scientific research.

But in him, his spouse, and relatives, Shen Qi is very conservative.

The most advanced technology that Shen Qi has mastered has been used on other humans and animals.

Biological Laboratory of Shen Qi Research Center.

Han Meng, who has been genetically edited with state-of-the-art technology, is studying the IQ of rats.

These rats, which have not been edited, have IQ differences between individuals.

After continuous observation by Han Meng and other experimenters, they divided the rats used for IQ experiments into three groups: smart group, ordinary group, and stupid group.

In the same T-maze experiment, the rats in the smart group were able to get out of the maze after a few attempts.

The normal group of rats needed to make more attempts, three to five times more than the smart group of rats.

The fool group of rats will never be able to get out of the T-maze, they are too stupid, and their effective memory and learning ability are at a very low level.

Although the T-maze experiment is simple, it is very classic, and this simple and classic experiment proves many academic views and gives birth to many academic theories.

The results of the research of animal behaviorists show that the IQ of rats is mainly reflected in memory and learning ability.

Factors that have been shown to affect the IQ of rats include the size of the hippocampus relative to the total brain volume of the rat, the cranial cortex and prefrontal cortex of the rat brain, and the connections between neurons.

Interestingly, in the case of natural selection, the females of the smart group mated with the males of the smart group forever, and their offspring inherited the high IQ of their parents and also performed well in the T-maze experiment.

Animal behaviorists and other branches of biologists believe that there must be some kind of uncracked biological code that controls the IQ of rats, making the behavior of smart rats and stupid rats significantly different.

The SHANK3 gene is one of these codes, or rather, the carrier of one of them.

The center's five biological experimenters have been studying the IQ experiment of rats for some time, survival of the fittest, natural selection, smart mice mate with smart mice, and they reproduce smart offspring.

If these rats are released into the wild, the survival rate of smart rats is definitely higher than that of stupid rats.

Experiments have shown that, apart from mutations, other parts of Darwin's theory are absolutely correct for now.

Because of the influence of the environment, is it possible for stupid rats to mutate into smart rats and pass on the mutated high-quality genes to their offspring?

There is such a possibility.

X-ray irradiation is a relatively common experimental method to cause genetic mutations, but this experimental method is not stable, and Shen Qi's biological team has not considered X-ray methods.

Director Shen's idea is to use the gene editing equipment, that is, XT80, to directly edit the SHANK3 gene in rats, as well as mismatch editing, nucleotide excision editing, base excision editing, homologous recombination editing, and non-homologous end joining editing...... Let's try them one by one, and each person is responsible for one or two editing experiments. "Han Meng was promoted to the number two person in the biological laboratory, and when Shen Qi was not in the laboratory, Han Meng was the boss.

"Okay, listen to Brother Meng's arrangement, I'll be in charge of directly editing the law. ”

"Then I'll do the base excision editing. ”

"I do ......"

The other four experimenters were very supportive of Han Meng, after all, Han Meng was the only genetically modified person in the laboratory.

"Without further ado, brothers, let's start doing it. ”

Han Meng, who was reborn, became an invulnerable person, his genes were changed, and he achieved genetic mutation through artificial methods.

Will it trigger new, harmful mutations, and how long will it live?

Han Meng didn't know.

Anyway, he is not dead now, and he is alive and kicking, and it is not worth it to go up to the eighteenth floor in one breath.

For the rest of his life, Han Meng only wanted to do one thing, to explore the mysteries of biology to the greatest extent and crack as many biological codes as possible.

The editing of the rat SHANK3 gene is different from the modification of the pathogenic gene made by Han Meng.

For example, Han Meng carried the disease-causing gene of prostate cancer before, knocked out this problematic gene, and injected the healthy gene into Han Meng's body. The operation of Tetris seems to be based on the pathogenic mechanism system that has been clearly explored by human beings.

Modifying IQ genes is another matter, and human beings have not explored a set of effective theoretical systems and experimental methods.

Uncultivated land may contain treasures.

Han Meng chose the sample of the common group of rats, and he used the mismatch editing method to try to edit the SHANK3 gene of the common group of rats.

Including Shen Qi, all the members of the Central Biological Laboratory came to the conclusion through experimental observations: smart mice, ordinary mice, and stupid mice, their SHANK3 genes do not look different at the molecular level.

Since there is no difference between nucleic acids and proteins at the molecular level, why can it be concluded that the SHANK3 gene affects the IQ of rats to a certain extent?

The study of this topic can be described as a chain of links, and new passwords are hidden in the passwords.

The most effective and perhaps most time-consuming way to crack a code is to experiment, experimenting constantly.

Han Meng first performed base pair detection between the parent strand and the daughter strand in order to find the special base members of the rats.

The new palm-sized base pair detector is running efficiently, and there are 5 in the laboratory, one for each of the 5 experimenters.

The five new base pair detectors were also purchased from Huahan Gene, which cost Shen Qi a total of nearly 10 million yuan.

It's worth the price overall, you give it a little bit of cells, and it can measure your three billion base pairs in the time you have lunch.

More than 20,000 human genes contain about 3 billion base pairs, and the detection objects of Huahan Gene's new base pair detector include humans, rats, dogs, cats, and monkeys...... You can also use this instrument to compare your base pairs with bananas, and you will find that your genes are 60% the same as those of bananas.

At present, the biological laboratory of Shen Qi Scientific Research Center only has input, not output.

Han Meng's genetic modification experiments have been done, but no papers have been formed that can be published.

"I hope that this experiment on rats will produce some academic results that can be reported. Director Shen's pressure is actually quite high, and we have to share our worries for him. Cui Hualin is also doing base pair testing, how much money Shen Qi has thrown into the laboratory during this time, he sees it in his eyes and remembers it in his heart.

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