After some conversation, Shen Qi was satisfied with Dr. Qu and hoped that Dr. Qu could come to the center to develop and engage in research in basic theoretical physics.

Dr. Qu is currently working at the Central South Institute of Mathematical Physics of the Academy of Sciences, and he promised Shen Qi to report to Yanda as soon as he completed the formalities there.

After dealing with the business of mathematics and physics, Shen Qi next cared about chemistry.

Regarding the benzoazazine compounds codenamed C01B, Lao Yan has completed a paper and handed it to Shen Qi.

The abstract of this paper is to the effect that:

"The synthesis process of benzoazazine was studied, and the new compound 4-oxo-5-phenyl-1,3,4,6-tetrahydro-6,10-methylene-2H-1,4-benzoazazane was prepared by condensation, hydrolysis, nitrification, substitution and other reactions with benzoazazine and nitrotrifluoromethanesulfonic acid as the starting materials.

After 10 steps, the target compound 4-oxo-5-phenyl-1,3,4,6-tetrahydro-6,10-methylene-2H-1,4-benzoazaza?, and its structure was confirmed by H-NMR (nuclear magnetic resonance hydrogen spectroscopy) and MS (mass spectrometry), with a total yield of 26.2%. ”

The body of the paper consists of two parts, the first part is the "synthetic route" and the second part is the "experimental part".

The synthesis route is mainly about the synthesis strategy design of the target product C01B, and some literature is cited as a support to show that the design of the strategic route is reasonable.

The experimental part is subdivided into 10 subsections from 2.1 to 2.10, which elaborate on the specific experimental operation of the ten-step reaction, and is written in great detail.

"2.6. 2-dicyclohexyl-diphenylphosphine (0.27mol) is used in 1,2-dimethoxyethane at 60 degrees Celsius for 2h. Under palladium-catalyzed conditions, sodium tert-butoxide with chemical equivalent was added......"

It has been refined to such an extent that any professional chemist who follows the steps in the "experimental part" will be able to obtain the target product C01B.

Shen Qi saw that there were two authors of this paper, Shen Qi in front and Yan Jun in the back.

Shen Qi revised the paper, putting Yan Jun's name in the front and his own name in the back.

The abstract and the text, Lao Yan wrote more rigorously, and Shen Qi had nothing to change.

This is a standard organic chemistry synthesis paper, which only describes the design of the synthesis route, the laboratory operation of each step of the reaction, the yield of each step and the total yield, and does not involve pharmacological aspects.

Toxicology, pharmacokinetics and other professional content need a large number of animal experiments and clinical trial data support, and large-scale industrial production needs to be verified by the process chemistry team.

After all the above things are completed, a drug can form the basic conditions for commercialization and have the possibility of being marketed.

Shen Qi positioned C01B as "a chemical test product in the preliminary laboratory stage", and as for the practical use and scientific value of C01B, we will talk about it in the next paper.

Shen Qi and Lao Yan synthesized C01B in a 10-step reaction in the laboratory, which is a new type of test product with the chemical name of 4-oxido-5-phenyl-1,3,4,6-tetrahydro-6,10-methylene-2H-1,4-benzoazoxaza?.

The overall yield of 26.2% has the value of follow-up research, and the paper should be sent out as soon as possible.

There are also the so-called four major journals in the international chemical community, which are Nature, Science, German Applied Chemistry (ANGEC), and Journal of the American Chemical Society (JACS).

"Nature" and "Science" are very practical journals, which only give synthetic routes, and do not give application value evaluation, so it is difficult for such chemical articles to be included.

Many of the chemistry articles included in Nature and Science are no longer pure chemistry, they are more like articles on pharmaceutical engineering or biochemistry.

This is very similar to the selection of the Nobel Prize in Chemistry in recent years, there are not many pure chemists who have actually won the award, and the winners come from various interdisciplinary fields such as physical chemistry, medicinal chemistry, and biochemistry.

ANGEC and JACS maintain relatively pure chemical properties, which can be seen from the IF value.

The IF values of Nature and Science are above 30 all year round, while ANGE and JACS hover between 10 and 15, and it is almost difficult to break 15.

After full consideration, Shen Qi asked Lao Yan to submit his paper to JACS in the United States.

"So hanging, your first chemistry paper will be voted for the big four?" Lao Yan has published more than a dozen articles in his career, the most of which was published in the British "Chemical Prospects".

According to Shen Qi's grading system, if the four major chemical journals belong to T0, then the grade of Chemical Outlook should be between T2~T1.

"It's not me, it's us. Shen Qi said, "Submit, hurry up, send it out early, and have original intellectual property rights as soon as possible." ”

Lao Yan wrote the synthesis steps of C01B in such detail that it can almost be regarded as teaching others to do experiments by hand.

If you copy this paper, you can also get a target product with comparable yield.

Therefore, it is necessary to send it out as soon as possible, take the lead in owning original intellectual property rights, and others can quote but not copy the full text in the future, otherwise it is academic plagiarism.

Mathematics, physics, chemistry, Shen Qi finished dealing with these tasks, and a day passed.

Ou Ye is waiting to give birth at home and has not come to Yan University to work recently.

Shen Qi didn't have to go to the courtyard to pick up his wife at five o'clock, he changed into sportswear and sneakers, and came to the sports field to do sports.

I haven't made love to my wife for eight or nine months, I don't have a lover outside, and I haven't done much health care, how did Shen Qi spend this period of abstinence.

Exercise, work, distraction, sublimation of inner desires, transformation of physical desires into spiritual satisfaction.

But this is very difficult to do, people have seven emotions and six desires, and scientists are also human beings.

Shen Qi even had the idea of using chemical drugs, a class of drugs that can effectively suppress sexual desire, and some countries use such drugs to punish sexual predators with chemical castration.

Fortunately, Shen Qi survived, as a scientist with seven emotions and six desires, his willpower is strong enough.

Ou Ye's due date is August 3, and in the blink of an eye, in late July, Shen Qi didn't go anywhere, so he stayed at home and worked in the academician's villa.

Ou Ye's parents also came to the capital and lived in Academician Shen's villa.

The villa is big enough, and it is more than enough for Shen Qi's two sons, Ou Ye's parents, and Cui Ping.

The villa was specially designed by the state for Shen Qi, and during this time, Shen Qi lived with Ou Ye Niang's family, and the four of them took care of a mother-to-be.

Ou Ye Niang's family originally lived in a villa, and they were very accustomed to living in Academician Shen's villa.

Shen Qi is not used to it, it is more comfortable for the young couple to live in a house alone.

Lao Ou's work is not very busy, he goes to work outside when he has work, and rests when he doesn't work.

Mother-in-law Lao Ye is a busy person, she is in the capital, and she will remotely direct the important business of her real estate company every day.

"Wife, don't call, your daughter will give birth soon. "Lao Ou has a lot of complaints about Lao Ye.

"No hit, no hit, mute. "Lao Ye is the head of the family, usually Lao Ou obeys her command, but today she obeys Lao Ou's arrangement.

"Dad, Mom, let Xiao Yezi go to the hospital in a few days. Shen Qi said.

"Yes. "Lao Ye has given birth to children, and she has experience.

As she was talking, Lao Ye's mobile phone rang, she glanced at the caller, and said, "This call must be answered, the deputy mayor's secretary called." ”

"Went outside to answer the phone, the phone had radiation. Lao Ou knew that his wife had more than one mobile phone, and he was very unhappy.

"Okay, good, it's done soon. Lao Ye went to answer the phone outside the villa.

Ou Ye's division of labor in her family is just the opposite of Shen Qi's family, Ou Ye's mother does business and starts a company, and his father works in a public institution.

"Damn's company is so big, it's normal to have a business. Shen Qi comforted Lao Ou.

"This mother-in-law has lost her money, she knows how to make money, does she want to be the richest woman or what?"

Lao Ou, you cow, my mother-in-law will come in after the phone call later, you kind of say the same...... Shen Qi poured a cup of tea for Lao Ou and let the old man dissipate his anger.

"To what extent is money an end? Your mother-in-law is very hard, and she is busy with work and business day and night for this family, which I understand. The business is so big, but one day she has to retire and be an old lady quietly. Of course, I understand your mother-in-law's mood, she wants to accumulate more family funds when she can still toss, so that Xiao Yezi has no worries about food and clothing in the second half of her life. Lao Ou loves and hates his wife, and he is distressed and itchy and wants to condemn her.

Shen Qi said: "Dad, don't you have me, I promise you, I can definitely let Xiao Yezi have no worries about food and clothing in the second half of his life, you two old people have worked hard all your life, and you should enjoy it yourself." ”

"Father to son, mother to daughter, it is natural, if our family background is not passed on to Xiao Yezi, who else can we give it to?" said Lao Ou of course.

The situation of the Ou Ye family is very similar to that of the Shen Qi family, an only child, who loves science and does not know how to do business, but cannot avoid the fate of inheriting the family property.

"That's the truth, but Xiao Yezi, how can she manage such a large-scale real estate company?" Shen Qi asked rhetorically.

Lao Ou: "Isn't there still you, you don't help Xiao Yezi, what's the use of asking you as a son-in-law?"

"I ......" Shen Qi had a headache, Ou Ye's mother's company was not an order of magnitude larger than Shen Qi's father's company. Shen Qi's own "father-to-son" business has not been rectified, and now he is facing the new topic of "mother-to-daughter" of his wife's mother's family.