Impossible, right?

How is this possible?

Damis Hassabi didn't believe what he saw at all, this had subverted his understanding of cognition, Xu Mang turned out to be the first place in today's competition, could he really solve the protein structure in a second?

Not only did he fall into doubt, but almost everyone who saw the news at this moment fell into doubt.

Damise Hassabi hurriedly made a phone call to Professor Matt to inquire about the situation, obviously the champion had already been arranged, why did they suddenly change their mind again, could it be that they secretly signed a condition with Xu Mang?

For Damis, he didn't believe that Xu Mang's broken box had such a powerful power, even more than AlphaFold, and it must be some agreement signed by the two parties that would make CASP make such a regression.

"Professor Matt!"

"What the hell is going on?" Demis Hassabi asked urgently, "Why did Xu Mang suddenly become number one?"

“...”

"I don't want that either. Professor Matt smiled wryly, "But that's the only way it can be... The data he submitted is so perfect that you can't find any flaws at all, what exactly is it... When the data is released the day after tomorrow, you can see for yourself. ”

Perfect?

Perfection created in a second with that broken box?

Time

Damis Hassabi has been shocked to the point of speechlessness, his AlphaFold actually lost to the broken box from Xu Mang, Huaguo, in the analysis of protein structure, which... If this news is made public, I am afraid that Google's stock market will plummet.

"What about tomorrow?" asked Daemis Hassabi, "Is it... Just watching him win the championship?"

"Don't worry!"

"I just had a conversation with someone. Professor Matt said: "Let Xu Mang analyze the complex formed by human polycystin 1 and polycystin 2, you also know that polycystin 1 and polycystin 2 are the pathogenic genes of polycystic kidney disease, and they will cause disease after mutation, let Xu Mang solve this problem, I think... The best. ”

“...”

Demith Hassabi fell silent, knowing very well what Professor Matt was talking about, which was the content of a paper written seventeen years ago, and the core of the content was not only to explain the structure and function of polycystin 1 and polycystin 2, subcellular localization, etc., but also to unsolve the status quo.

Polycystin 1 is a protein with 4,302 amino acids and 11 transmembrane helices, and these two numbers alone represent impossibility, let alone let Xu Mang analyze the structure of the complex formed by polycystin 1 and polycystin 2.

Rest assured!

I was completely relieved!

Daemis Hassabi breathed a sigh of relief, he was originally quite nervous, thinking that this time the championship would be taken away by Xu Mang, but now he completely abandoned this thought, in his cognitive view, Xu Mang and his broken box could not cross the protein of the eleven transmembrane helix.

"But," Professor Matt sighed, and said helplessly, "that piece of equipment of his is really powerful, and it can solve the structure of the Tau protein in a second... How did he do it? Could it be that from this moment on, the symptoms of AD, which human beings have so far been helpless, are about to come to an end to their dreams?"

Hearing Matt's words,

Damis Hassabi didn't speak, his expression was a little embarrassed at the moment, he felt uncomfortable, and at the same time he was a little curious, Tau protein structure?

"Ahem..."

"Professor Matt?"

"Can you briefly elaborate on the structure of the Tau protein?" asked Demis Hassabi.

"Actually, it's a peculiar structure... The three-dimensional structure analyzed by Xu Mang is as follows: many individual AB layers are staggered into a so-called precursor, and then the two precursors are wound with each other to form a fibril. Professor Matt said earnestly: "According to this structure... If several of these fibrils are tangled together, then this forms the typical deposits or plaques in the brain tissue of AD patients. ”

"Fibrils?"

Daemis Hassabi underestimated a sentence, and as for what Professor Matt said afterwards, he didn't listen to it at all, and he clearly felt that the gap between his AlphaFold and Xu Mang's small broken box was not the same grade at all.

Don't...

In the future, in the field of artificial intelligence, will also be squeezed down by Xu Mang?

Is he a Google nemesis, the terminator of stocks?

meanwhile

Xu Mang just finished talking to Professor Smith on the phone, and briefly talked about how he wants to fulfill some of his obligations as an honorary professor at Princeton University, such as donating the world's most powerful artificial intelligence, the Xu Man system.

At first, Xu Mang opened his mouth and asked for $100 million, but under the influence of Professor Smith, Xu Mang decided to charge a symbolic amount of $1.

Professor Smith was impressed, and then resolutely refused.

One dollar,

That's certainly not a good thing.

But... At this time, Professor Smith received a call from the professor who was attending CASP at the University of Maryland.

"Smith!"

"Professor Xu Mang's artificial intelligence is simply... It's simply stunning. The professor said, "I want you to help me do something, you have a good relationship with Professor Xu Mang, can you get information about artificial intelligence from him?"

Smith:???

This...

Such a coincidence?

Professor Smith looked dazed and said helplessly: "I just rejected his kindness, originally he planned to sell the artificial intelligence in his hand to Princeton University for a dollar as a research reference..."

"What?"

"You... You refused?"

Hearing this, the professor instantly collapsed, and an opportunity to learn about the world's most powerful artificial intelligence flew away from his hand, and no one could calm down.

"I'll hang up first!"

Words fall,

The call was directly hung up, and Professor Smith called Xu Mang, so that he finally reached a deal again, symbolically buying the 'Xu Man System' in Xu Mang's hand at a price of one dollar, and Smith was a little confused about this matter.

Why?

Why would he do it?

In Professor Smith's cognitive view, Xu Mang is not such a generous person, on the contrary, he is a very stingy person, but his stinginess is limited to Europeans and Americans.

At half past five in the afternoon,

Xu Mang was paralyzed on the bed, motionless like a king, this is when he received a phone call, it was a call from a professor from Princeton University who participated in the CASP, inviting him to have dinner with him, Xu Mang directly refused.

No way...

In case you have a bad stomach and you are hospitalized that night, then the meal is too expensive... 1.5 billion!

I can't afford it.

night

Come quietly,

Xu Mang received a call from Yang Xiaoman, and the content was all some words that you love me, which is quite abusive to dogs.

"Just turned down an invitation from a professor at Princeton University. Xu Mang said seriously: "I hope I will have dinner with Brother Chuan Xiao and their team, just kidding... I can't afford to eat this meal, 1.5 billion dollars... If he hacked him, wouldn't it be a big loss? ”

"Hmm!"

"It's better to be careful. Yang Xiaoman said with concern: "Eat some compressed biscuits, don't eat too much, this kind of thing is easy to make you die." ”

"Don't worry!"

"I'm not brain-dead. Xu Mang smiled and said, "Wife... When I get home, I want to eat braised pork!"

“...”

"You shouldn't eat it first... Huh?" Yang Xiaoman's words carried a trace of affection, and there was a trace of longing for Xu Mang in his gentleness.

Xu Mang: ???

...

Following

Xu Mang and Brother Chuan Xiao went to the arena, and met many people along the way, almost all of them looked at the two of them with frightened eyes, these people couldn't imagine that Xu Mang had successfully advanced to the second day's competition, and he was still the first place.

What to do?

Is he going to win the championship?

However, Demis Hassaby, the head of Song's artificial intelligence company DeepMind, was not worried, he already knew what Xu Mang was going to draw, which was a protein that crossed the membrane helix eleven times, and it was a complex formed by polycystin 1 and polycystin 2.

I'm sorry

Xu Mang can't do it at all!

Re-draw the number, this time Xu Mang drew the sixth, according to the meaning of Huaguo, today must be very smooth.

"Huh?"

"I... it!"

Xu Mang was shut up after getting the question, which seems to be too complicated, right?

There are 4,302 amino acids, and there are also proteins that contain 11 transmembrane helices, and if it is just that, it will be okay, and the problem needs to be solved to analyze the structure of the complex formed by polycystin 1 and polycystin 2.

I...

Nima!

In order not to take money, it is really a matter of everything!

"What's wrong?"

"I see there's something wrong with your expression!" Brother Chuan Xiao asked curiously, "Is it... Tragedy?"

"See for yourself!" Xu Mang handed the question to Brother Chuan Xiao, and the next second Brother Chuan Xiao was autistic, standing there stunned.

"it!"

"Are they crazy?" Brother Chuan Xiao said angrily, "How can this be solved?"

Alas...

How to fix it?

The solution must be solvable, but it will take a little time, I don't know how much, but it definitely can't be done in a second, of course... There can be miracles.

Then

Professor Matt, the founder of CASP, appeared on the field this time just to see Xu Mang's embarrassment.

"Professor?"

"What questions did you give Xu Mang?" A young man standing next to Matt found Xu Mang with a confused face on the field, and asked curiously: "He is even more confused than yesterday, as if... It seems to be over. ”

Professor Matt smiled and said indifferently: "This is a problem more than ten years ago, and it has not been solved so far, and Xu Mang needs to analyze the structure of the complex formed by polycystin 1 and polycystin 2. ”

"There's absolutely no way he'll do it!" Professor Matt said carefully, "I swear with my life!"

Hearing Professor Matt's words,

The young man looked at Xu Mang in horror, it seemed that this time he was really going to be at the bottom.

......