Lu Weibei and Xue Mianmian made an appointment on Wednesday.

On Wednesday morning, Lu Weibei came to the Third Hospital to pick up Xue Mianmian and was discharged. As soon as he left the hospital gate, he coldly answered a call from Lao Hu, the head of the monogenic disease department next door.

The two don't know each other well, so it must be a business matter. Lu Weibei motioned for Xue Mianmian to go back to the hall and sit and wait for her, and then went to a quieter place to answer the phone.

Here's the thing.

The husband of Chen Xue, the director of the pediatric department of the Third Hospital, Fu You, 49 years old, went to the hospital for a check-up a month ago when he felt nauseous and wanted to vomit.

I thought it was just gastritis, but I didn't expect it to be an advanced stage of diffuse gastric cancer.

Chen Xue studied medicine and knew that the prognosis of this disease was extremely poor, so she immediately arranged for him to be hospitalized and underwent a total gastrectomy.

After total gastrectomy, Fu You's small intestine and esophagus were directly connected together, and the alkaline intestinal fluid and bile were reversed, burning his throat uncomfortably.

The two have a daughter, only 21 years old, still in college, and do not know about her father's illness.

What's even more frightening is that some diffuse stomach cancers can be inherited.

If there is a pathogenic mutation in the CDH1 gene in the human body, there is a high probability that people will develop this diffuse gastric cancer. This inherited cancer is an autosomal dominant disease, which means that parents who carry the mutation have a 50% chance of passing the mutation to their offspring, making their offspring also a high-risk group for the disease.

Chen Xue didn't dare to be sloppy, so when she was diagnosed, she took Fu You's blood and sent it to her colleagues, and asked her colleagues to help, and took her daughter Fu Bing's blood sample in the name of physical examination, and sent it for genetic testing together.

And early this morning, Chen Xue received the genetic test reports of the two. He has a suspected pathogenic mutation in his СDH1 gene.

Because many mutations occur in a single lineage, and the incidence of this type of disease is very low, not all rare mutations can be accurately classified as pathogenic and non-pathogenic.

Therefore, generally speaking, the pathogenicity of mutations will be divided into five grades, pathogenic, suspected pathogenic, unclear meaning, benign meaning, and benign. The pathogenicity of a mutation can be interpreted based on the biology of each mutation, as well as previous case reports.

The "suspected pathogenicity" of Fu Yu is the one where the evidence of pathogenicity is relatively clear, but he is not completely sure.

And Fu Bing's test report showed that she also carried this mutation that was suspected of curing the disease.

For Chen Xue, this is tantamount to a bolt from the blue.

Because diffuse gastric cancer has an insidious onset in the early stage, there are no symptoms at all, the morphological changes of stomach cells are not obvious, and even gastroscopy is often missed, so if you want to prevent the occurrence of this disease, you can only perform a prophylactic total gastrectomy.

Total gastrectomy has a package of sequelae.

She may have regurgitation like her father, she may have frequent diarrhea, she may have symptoms of dumping syndrome such as abdominal discomfort, palpitation, dizziness, anemia and nutritional disorders, not to mention, which means changes in her diet and lifestyle habits throughout her life.

On the one hand, Chen Xue felt sorry for her daughter, and on the other hand, she had a sense of luck, hoping that this was not a non-disease-causing site.

Chen Xue has to take care of her painful husband while trying to find a way to hide from her daughter, tired of coping, she has been very tired during this time, and now that she has taken this report, the depression of the whole person is written on her face.

Lao Hu came to talk to her about cooperation today, and when he saw that her face was wrong, he asked a few words and knew about it.

As soon as he heard this, he immediately recommended the "half-immortal" Lu Weibei.

"I can take it, but I have to see it. You know, I only do face-to-face consultations. If they want to hide it from their daughter, it's not easy to do it. "Lu Weibei always refuses to save people, but this time the conditions are restricted, which makes me a little worried.

"It's okay, just find a way to get you to meet, don't tell the truth. "Lao Hu doesn't care about the authenticity.

Lu Weibei pondered for a moment and said, "That's not impossible, but you must have an insider to accompany you." ”

"Okay, I'll let Director Chen accompany me then. I'll contact her now! Thank you, I'll be in touch in a moment!" Lao Hu agreed.

"Wait a minute, wait a minute, you don't want to make an appointment today, I'm on vacation today, I'm not in the company. Lu Wei said in a hurry.

But Lao Hu had already hung up the phone.

Lu Weibei walked back helplessly, while chasing the phone.

Before the phone was connected, she saw Xue Mianmian.

But she wasn't sitting alone. Next to her sat a woman with short curly hair and a white coat. The woman looked to be in her fifties, and she looked a little haggard. The two looked very familiar, and Xue Mianmian held the woman's hand with both hands, as if comforting something.

At this time, Lao Hu's voice came from her right rear, "Director Chen, I've got in touch, do you have time? Let's go see her." ”

Lu Wei turned around in surprise.

On the other side, Chen Xue raised her head eagerly, and Xue Mianmian also looked over with an inquiring look.

Seeing this scene, even Lao Hu was stunned.

The four of them looked at each other for a while, and then slowly dismantled their respective identities.

It turned out that Xue Mianmian and Chen Xue had already met at the hospital's party, and they were familiar with each other. When she came back to wait for Lu Wei to say goodbye, she happened to see Chen Xue's bad look, so she came over to chat a few words.

Listening to Lu Wei's other concerns, Xue Mianmian patted his thigh and proposed, Fu Bing went home today, just went to Chen Xue's side to cook a hot pot, and did it without a trace.

So in the evening, Lu Weibei completed her first "dinner at a stranger's house" in her life.

Anyway, she was still a little cramped, fidgeting in her seat.

Xue Mianmian was quite comfortable, and talked to Chen Xue to ease her mood.

"I'm back. With the sound of the door opening, a lazy voice sounded.

"Are you back? Are you tired from class today, let's wash your hands and eat." Chen Xue got up to greet her.

"What's so tiring in class? The teacher said above, and I listened to it below, and it wasn't an exam. Fu Bing said lazily.

"My dad didn't come back today......?" she threw her bag in the hallway, turned around her neck, and walked slowly into the dining room, where she saw the two people in the restaurant, and her complaints came to an abrupt end.

"Hello!" Xue Mianmian smiled and waved his hand to greet her.

Lu Weibei stood half a step behind Xue Mianmian, and also smiled and waved his hand.

Fu Bing's face stiffened for a moment, then he reluctantly said hello and went straight to the bathroom.

Chen Xue explained a little abruptly, "We are both busy with work, and sometimes we are too strict to educate, and this kid has a bit of an awkward temperament. But she is actually a good child, with a very soft heart and good grades. ”

"Children are like this, and I was angry when I was a child. It will be fine in a few years. Don't be, you were like this when you were a child, right?" Xue Mianmian said.

Xue Mianmian thought about the vague history of going to the house before he was five years old and nodded.

After a while, Fu Bing took a plate and brought four bowls of dipping sauce, "My family has always been my dipping sauce, and my mother's sauce is not delicious." I don't know if you're used to eating or not. ”

Lu Weibei took the bowl honestly, but Xue Mianmian looked at her with a smile with shining eyes.

Fu Bing turned his gaze uncomfortably.

Looking at the red oil on the plate, Lu Wei didn't beat a drum in his heart, leaned into Xue Mianmian's ear and said, "This is spicy, can you eat this?"

Xue Mianmian raised her eyebrows, "Of course you can! Let me tell you, people can't lose their mouths when they live." ”

Although the voices of the two were small, the table was not big, and they were still heard by Chen Xue's mother and daughter.

"Mianmian, can't you eat spicy? I remember you used to eat it?" Chen Xue said in surprise.

"No, no, my stomach has been upset for the past two days, so don't worry about it. Xue Mianmian didn't want to use her condition to add to the blockage, so she hurriedly found an excuse to cover it up.

Lu Wei didn't look at her sadly.

Fu Bing listened, didn't say anything, turned around and mixed a bowl of dipping sauce without chili peppers and put it in front of her.

Xue Mianmian smiled and thanked him, but still ate the bowl of chili seasoning.

Fu Bing raised his eyebrows and took care of his own food.

"By the way, did you read the news? Angelina Jolie, what did she say, hereditary breast cancer, and then she cut her breast?" Xue Mianmian pretended to bring up the topic casually.

"Yes, yes, we are also talking about this in the hospital, and everyone is discussing whether to have this surgery if it is themselves. Chen Xue hurriedly agreed.

"It's been the news from 800 years ago, and you're only talking about it now, it's too outdated. Fu Bing said expressionlessly.

The scene was cold for a moment.

Fortunately, Xue Mianmian is a person who is becoming more and more courageous. She giggled and said, "Really, then I'm really outdated." So you say, if it's you, are you going to do this kind of surgery? If it were me, I'd probably do it too. It's too much to get cancer. What about you?"

Lu Weibei said according to the lines that had already been written, "I guess I will do it too." ”

Xue Mianmian nodded with satisfaction and asked again, "Xiaoice, what about you, do you do it?"

"I don't know. Fu Bing lowered his head to eat the vegetables, and he didn't raise his head.

"Xiaoice, how to speak, be polite to the guests. Chen Xue intervened.

Fu Bing put down his chopsticks and raised his head, "I really don't know." If something really happens, don't you say no? No one in our family has ever had breast cancer, so what the hell are you doing?"

Lu Weibei said solemnly, "I don't think it's okay to make a decision now, everything is done sooner rather than later, just in case." And I think you should have this surgery, I think everyone should have this surgery, after all, it's more important to be alive. ”

Chen Xue's heart twitched, her chopsticks almost didn't hold it, and she looked at Lu Weibei without blinking.

Lu Weibei glanced at her solemnly.

Chen Xue closed her eyes dejectedly, and when she opened her eyes again, her eyes were red, "Don't be right, if it were you, you should also have surgery." ”

"I don't do it. Fu Bing's reverse scales were finally stabbed, so he simply confronted his mother.

"It's up to you, you have to do it, and you have to be tied to the operating table!" Chen Xue said.

"Okay, okay, you're up to you. Fu Bing said perfunctorily, "Anyway, there is no glimpse of the eight characters, how happy you are." ”

During the conversation between the mother and daughter, Lu Weibei kept staring nervously at the top of Fu Bing's head.

If there is no number on the top of Fu Bing's head, eighty percent of this operation will have no effect on her, which means that she can escape......

Lu Weidon't blush.

Because there were numbers above Fu Bing's head.

Slowly climbed from 292 and stopped at 18253.

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