Ai Xiao really bought a sugar gourd for Warlene and came back, and Warlene couldn't cry or laugh: "I thought you were just talking, you still take it seriously, take it back and give it to your children, how old I am, I have long lost interest in this." ”

"What's wrong with people when they grow up, they can't eat delicious food?" Ai Xiaosai gave Warlyn a sugar gourd, and he also took a sugar gourd to eat first, "I will never favor my children because they are young, and leave everything delicious to them, otherwise they will develop a selfish temperament, and if there is delicious food at home, even if it is small, everyone will eat it together." ”

Ai Xiao has three children, the eldest daughter was born to her and her first husband, after the divorce, she took her daughter to marry her current husband, and gave birth to a pair of dragon and phoenix fetuses in the second year of marriage, the eldest daughter has gone to elementary school, and the dragon and phoenix fetus have also gone to kindergarten.

Okay, if you have a reason, just eat, Warlene also bit a sugar gourd, in front of the strong Ai Xiao, Warlene has always been the one who obeys the arrangement.

Warlene asked Wang Yunshu about not being able to conceive a child, and Ai Xiao sighed: "The doctor said that there are antibodies in her serum, and this antibody pushes the child out as an intruder, you say, how can this thing conceive a child." ”

"Antibodies?" Warlene had heard Zhao Ping talk about this when she was chatting, but because this kind of thing was too far away from her, she went in and out of her left ear, and she didn't go to her heart at all, and now when she heard Ai Xiao say this, she remembered that there was such a thing, but unfortunately she was also confused.

Ai Xiao was still sighing: "Tell me, how can there be something in this mother's body that doesn't want her own children, what's the matter?"

"Wait," Warlene interrupted Ai Xiao's emotion, "Antibodies don't happen for no reason, I'll ask the doctors at our hospital first." ”

"Okay, then you can ask," Ai Xiao explained the situation, "This antibody is still tested in the regional hospital, our county hospital does not have this technology, it costs a lot of money in a big hospital, and the doctor can't understand what the doctor said, Yun Shu's mother-in-law just urged Yun Shu to go home quickly, don't spend money in vain, so Yun Shu didn't understand it at all." ”

Warlene used her landline at home to call the obstetrics and gynecology department of Z Hospital, and Zhang Ping happened to be on duty, and when she received the call, she complained to Warlene: "Didn't you say that you only learned to come back during the Chinese New Year, how did I hear someone say that you have to study for a while after the Chinese New Year to come back, I stayed alone in the dormitory and was bored to death, you hurry back." ”

Warlene didn't believe Zhang Ping's nonsense: "Who are you fooling, I don't know who it is and her secretary I am, I have long forgotten who I am." ”

The two joked a few more words, and Warlene talked about Wang Yunshu's condition.

Listening to Warlene and Zhao Ping talking very casually, Ai Xiao intuitively felt that Warlene had a good relationship with this doctor, and this doctor should not be going around the bush with Warlene, but would talk straight, so she directly pressed the speakerphone and wanted to hear what the doctor had to say in person.

Zhang Ping was dissatisfied with Wo Lin: "You can't tell me clearly, I haven't seen the patient, and the past medical history is not clear, how can I draw conclusions to you casually." ”

Warlene laughed: "I only know so much about the small situation, you can tell me all the possible causes." ”

"Okay, while I haven't gone to surgery yet, I'll give you a simple science popularization, so that you can give your hair a little explanation. "Zhang Ping has always been straightforward.

Antibodies associated with miscarriage are: anti-sperm antibodies, anti-endometrial antibodies, anti-ovarian antibodies, anti-zona pellucida antibodies, anti-trophoblast antibodies, anticardiolipin antibodies, and antichorionic gonadotropic antibodies.

Normally, women do not produce anti-sperm antibodies, but when there is inflammation and damage to the female reproductive tract, antibodies are also produced in the woman's serum and cervical mucus, and the presence of such antibodies can prevent sperm from penetrating the cervical mucus and fertilization.

Anti-endometrial antibodies are autoantibodies that target the endometrium and cause a series of immune responses.

Antibodies are produced for two reasons: on the one hand, because of the ectopic endometrial stimulation system, and on the other hand, because of the body's immune system, which is an autoimmune deficiency.

The endometrium is the place where the embryo implants and grows and develops, but in pathological states, such as endometritis, endometriosis and adenomyosis, it can be converted into antigens or haptens to stimulate the body to produce corresponding antibodies.

The presence of anti-endometrial antibodies in the body can lead to infertility, abortion or miscarriage.

Many patients are unable to get pregnant again because they have had an abortion during their first pregnancy, and most of these secondary infertility patients are due to the production of antibodies in the body.

Anti-ovarian antibodies are autoantibodies to the target antigen in ovarian granulosa cells, oocytes, luteal cells and interstitial cells, which can affect the development and function of ovaries and follicles, resulting in premature ovarian failure, irregular menstruation, follicular dysplasia, and even non-ovulation to produce anti-fertility effects, which in turn lead to infertility.

Causes of anti-ovarian antibodies: chromosomal abnormalities, lack of ovarian development or congenital defects, positive anti-ovarian antibodies due to oophorectomy, ovarian infection, or anti-cancer therapy, complications with other autoimmune diseases, such as thyroiditis, rheumatoid arthritis, etc., gene mutations, ovarian blood supply disorders.

The egg cell is surrounded by a layer of non-structural eosinophilic gelatin-like substance, known as the zona pellucida, which is secreted by the egg cell and its surrounding follicular cells during the growth and development of the egg.

The zona pellucida is not only highly immune, but also induces the body to produce a global or local cellular and humoral immune response, producing anti-zona pellucida antibodies.

Anti-zona pellucida antibodies prevent sperm from attaching, prevent sperm from penetrating the oocyte, and harden the zona pellucida and interfere with sperm implantation when fertilization occurs.

Infertility caused by anti-zona pellucida antibodies is an autoimmune disease in the final analysis, causing the embryo to be encapsulated in the zona pellucida and unable to implant, and it is easy to cause intrauterine termination or miscarriage of the fetus after pregnancy.

Positive anti-trophoblast membrane antibody is a kind of closed antibody that causes the mother to produce a protective effect on the fetus through an immune response, resulting in miscarriage and inability to conceive normally.

Studies have shown that anti-trophoblast cell membrane antibodies are significantly higher in the serum of patients with unexplained miscarriage than in normal pregnant women, indicating that there is a close relationship between the increase of antibodies and miscarriage.

Anticardiolipin antibody is an autoantibody that targets negatively charged cardiolipin on platelets and endothelial cell membranes, and can be used as an auxiliary diagnosis of recurrent miscarriage, thrombosis, thrombocytopenia, and lupus encephalopathy.

Patients with positive anticardiolipin antibody are more likely to form thrombosis due to enhanced platelet agglutination and increased thromboxane, and are prone to miscarriage during pregnancy.

Positive anti-chorionic gonadotropin antibody is immune infertility, which can easily lead to miscarriage and fetal termination after conception.