Chapter 508: A Tragic War of Immunity
"The Ebola virus uses healthy somatic cells as raw material warehouses and manufacturing factories for virus processing, constantly replicating itself," Zheng said. When the raw materials in healthy cells are used up, cells lose their value. At this point, the Ebola virus directs the cell to synthesize a lytic enzyme that dissolves the cell's membrane, but when the cell membrane is melted away, a large amount of the virus spills out of the enslaved cell and attacks other cells. ”
When Zheng Xuanyu said this, Gao Siqi added: "This is the most terrifying thing about the virus, it has very few base pairs, but it can command and control somatic cells that are more advanced than it to serve it. ”
Zheng Xuanyu continued to explain with a microscopic video: "Is the human immune system so fragile? Of course you are not, when the infected cells burst out with more viruses, it will also anger the human immune system. At this point, other immune cells in the human body, such as white blood cells, will launch a frantic attack on the Ebola virus. ”
"But unfortunately, these immune defense tools and the Ebola virus are two different lines, and if you can't identify Ebola, you can't attack it, just like you scold a foreigner in Chinese who is different from the Chinese language, and others won't be angry if they don't understand it, these immune defense tools are ineffective against the Ebola virus." ”
"It is ineffective against the Ebola virus, but it is extremely harmful to humanity itself. The surge of immune cells can lead to the breakdown of healthy cells, such as red blood cells, and a large number of healthy cells are also attacked by immune cells, which is why many patients with Ebola virus have ecchymosis or even direct bleeding. The healthier the person, the stronger the immune system, the more likely it is to self-injure at this time. ”
"This is just the first step in the Ebola virus's invasion of human health. In the second step, Ebola attacks lymphocytes, the smallest white blood cells. The main performers of almost all immune functions of the lymphatic system are the front-line soldiers who fight against external infections and monitor cell mutations in the body, and the captured lymphatic system will give instructions to the body's immunity to stop making and producing immune cells. ”
Zheng Xuanyu said here and sighed: "This is the most critical part of the game between Ebola and the human immune system, because in the human immune cell, not all cells are not Ebola's opponents, and there is one cell that can fight with Ebola and even gain the upper hand - natural killer cells." ”
"However, because the lymphatic system has issued instructions to inhibit the production of immune cells, many natural killer cells that are still in their juvenile state stop growing, and the natural killer cells that are mature have no combat effectiveness, so they are captured and strangled by Ebola. ”
Xiao Ming said: "In fact, at this step, the human immune system is already finished, right?"
Zheng Xuanyu said: "It can be said that human beings still have the last counterattack - to break the cauldron and fight against the water. ”
"The main way for the virus to attack the cells of the human body is through the blood, and the human immune system is also aware of this after the defeat of the human immune system, and at this time a very dangerous thing happens, in order to avoid systemic infection, the permeability of the human blood vessels will increase, so that a large amount of blood will penetrate into the body through the blood vessel wall, which is a backwater battle. ”
Through Zheng Xuanyu's description and the demonstration of the microscopic video, Xiao Ming was able to realize that this was the most tragic battle in the history of human immunity.
This kind of tragedy is like the destruction of the country and the death of the family, the palace is surrounded by enemy legions, and the emperor has no soldiers in his hands, so he can only bring his concubines and children to kill the enemy in person.
But this approach is undoubtedly self-defeating.
A large amount of blood enters the body through the walls of blood vessels, which can cause massive bleeding in the internal organs. Edema and other irreversible pathological reactions, at this time, the patient is close to death. Even if Ebola slows down the attack on all cells in the body, humans will die due to the collapse of the immune system and blood circulatory system.
At the end of the microscopic video, the dead Ebola infected person is seen in the video, skinny and with ulcerated, blistered and swollen skin.
Zheng Xuanyu finally concluded: "This is the terrible thing about the virus, the simple structure but the ability to use all the resources of the human body to serve itself, in fact, not only the Ebola virus, but also the most terrible place for deadly viruses such as influenza, HIV, smallpox, etc. ”
Xiao Ming said: "This is the same as a computer virus, just a few simple codes can make the entire computer system serve it. ”
Gao Siqi talked about the vaccine problem in Maple Leaf Country, "There is also some progress in vaccine research in Maple Leaf Country, but the cost is high and there is no large-scale application. Moreover, the Ebola virus also has a strong ability to evolve, its receptor glycoprotein may change, and it is difficult for us to grasp the real effect of the vaccine.
Moreover, the vaccine can only be used before the disease, and it has no effect if it is used after the disease, which is also a common problem of most virus vaccines. ”
Xiao Ming has a clear understanding of life science, and he knows the power of the virus through the descriptions of Zheng Xuanyu and Gao Siqi, and it is very unsafe to prevent the combination of glycoproteins and receptors on the surface of the virus, because the glycoproteins on the surface of Ebola will mutate with the change of the environment.
"What about your plans?" Xiao Ming asked.
Gao Siqi was a little tired at this time, she said: "To find the key to the core of the virus, the genes of the virus must have an answer in some sense, and their arrangement and expression form will definitely tell us the answer." As long as we find the core key, knowing that it is a certain gene expression that can control the human cells to serve it, then we are half the battle, and the same way can be applied to conquer other viruses, which is the universal law of virus life.
There are also technicians in the life science laboratory in Nananfei, who will send the detailed Ebola genes, and will also go through a series of experiments to determine how the genes are expressed, and humans will one day be able to defeat the virus. ”
Xiao Ming said: "You should rest early, and during this time, you can take a vacation in it, play games, visit the virtual business area, and relax." ”
Zheng Xuanyu smiled sweetly at Xiao Ming and said, "You also rest early, I have to sleep, I'm sleepy." ”
Exiting the virtual community, Xiao Ming sat on the sofa and fell into deep thought.
The core genetic material of the virus – DNA and RNA – must be stable, they are the key to pathogenesis, while the genetic material that evolves and mutates is only changed to adapt to the host.
The only thing that can defeat the virus is the human immune system itself, which should be the starting point for research in life science laboratories.