Chapter 212: Biomimetic Cornea

Myopia can be caused by a variety of reasons, so I won't discuss them all here.

And why myopic eyes can't see clearly in the distance needs to be talked about.

Objects from all walks of life in nature reflect different light and dark rays under the illumination of light, and these rays are focused on our retina through the refraction of cornea, lens and other structures, so as to obtain a complete and clear image of objects.

Of course, there are a series of electro-optical changes that will take place during this period.

In people with myopia, the focus of the lens does not fall on the retina, but in front of the retina (it can be imagined that the lens concentrates the light too much), so it is not clear to see clearly.

A concave lens (myopia lens) is added in front of the eye, and then the parallel light from the outside is diverged before entering the eye, correcting the excessive concentration of light, so that the light can be concentrated on the retina after passing through the lens, so that normal vision can be restored.

At present, the relatively reliable and safe method for myopia on the market is laser surgery.

The principle is to ablate a part of the tissue in the central area of the cornea (corneal stroma) through a cold laser, so that the center of the cornea is thinned, so that a concave lens similar to a myopia lens is formed on the cornea, thereby correcting myopia.

But surgery comes with a variety of uncertainties, both from the surgery itself and from the outside world.

For example, a corneal flap (which you can think of as a cap) cut by laser surgery does not heal completely;

Blurred vision due to corneal deformation after surgery;

After surgery, the corneal flap (the cap that is incised) is very fragile and can easily cause the cornea to detach if it is hit by an external force (such as an eye-sealing fist).

In addition, it can be accompanied by some problems such as inflammation and dry eyes.

Of course, despite all the dangers, there are still many people who undergo laser surgery.

Because wearing glasses is really too much trouble.

In addition, people who wear glasses for a long time will look very ugly as if their eyeballs bulge out after removing them.

……

After analyzing and studying the most advanced theoretical technologies in the world today, Xiaobai combined with real technology to find the best way to treat myopia - bionic biological cornea.

This technique does not require surgery, the doctor places a biocornea, which resembles a concave lens, into the eye, and then rinses it with saline, and within a minute, the biocornea spreads throughout the eyeball.

It is truly painless and non-invasive, and there are never any after-effects.

As for the technical principle, it is mainly to print the shape of the patient's cornea through 3D bioprinters and bioinks, and then cultivate it through stem cell technology.

The process takes less than ten minutes.

The real difficulty with this technique lies in the bioink.

As a material, it needs to be hard enough to hold its shape, but also soft enough to squeeze out of the 3D printer's nozzle.

Foreign scientists have been experimenting since 2010 and have spent a whole decade, but so far they have not found a truly suitable bioink.

But what about Xiaobai?

It took less than three days to find the most suitable bioink drawing, a combination of alginate and collagen, through data simulation, and then reverse engineering.

Three days versus ten years, which is why it is said that science has taken an inflection point.

Although the drawings are out, there is still a lot of work to be done.

There is an urgent need for biological researchers to grow bioinks and print them out with 3D bioprinters for experiments.

After the experiment is successful, animal experiments will be carried out.

Finally, human experiments can be carried out.

In total, the time to go to market is not short.

……

No. 515, Science and Technology Avenue, Industrial Park, Minxi District, Xinghai Institute of Life Sciences.

This is the commercial plot purchased by Xinghai Technology, covering an area of more than 20,000 square meters and a design construction area of 50,000 square meters.

As a private research institute, the area is not small.

It is currently under construction, and with the investment regardless of the cost, the main body of the building has been completed and is expected to be ready for occupancy by the end of the year.

Like Xinghai Artificial Intelligence Technology Laboratory, although Xinghai Life Science graduate students have the word "Xinghai", they actually have no affiliation with Xinghai Technology, and the two laboratories are independent.

The technology researched in the laboratory is also licensed to Xinghai Technology for market development.

The technical agency fee of Xinghai Technology every quarter is remitted to his overseas investment account, and then the investment account invests in Xinghai Technology through a series of legal channels.

The reason why I took off my pants and farted and went around in such a big circle is, of course, for a reason.

The institute has not been able to move in for the time being, but has rented a floor in the adjacent park science and technology building as a research institute.

The person in charge here is called Marven, a lewd fat man with glasses.

He is 27 years old this year and a graduate of bioengineering at SU University.

The discipline of bioengineering is known as the first of the four most pitiful majors of "biochemical environmental materials", which is not a joke, with low employment rate, low salary, low demand, and it is particularly hard to soak in the laboratory all day.

Not to mention a 211 school like Su University, even if it is handed over by 985 and Qingbei, it still has no future.

After graduating from university, Marvin was unemployed and could not find a job at all.

He lives in Sioux City and usually makes a living by doing odd jobs.

Playing games, watching Japanese anime, masturbating, and living a very sad life.

As the days passed, the whole person gradually became abolished.

Marven didn't dare to go home, he didn't even dare to answer his parents' phone calls, life was like sailing in an endless dark ocean, and he couldn't see a little hope.

Until the end of last month, he suddenly received a strange phone call asking him to work at a biological research institute in Zhonghai.

Marven thought it was a joke at the time, but life was so dark that he had nothing to lose, so he bought a train ticket and came to Zhonghai.

Life is like a magic movie that won't be repeated, it's full of variables.

When he arrived, he found that there was no one else in the institute but him.

And the stranger who asked him to come to Zhonghai not only gave him a job, but also put him in charge of the recruitment of personnel for the entire research institute.

Although Marven was very confused, he still completed it according to the requirements.

The researchers he found were basically his depressed classmates and brothers.

But as of now, he still doesn't know who the owner of this life science research institute is.

And why did you ask him, a person who couldn't even count half a bucket of water, to manage it?

At half past two in the afternoon, another batch of experimental equipment arrived at home, and Marven and several colleagues and classmates went downstairs to move the goods.

A large truck was parked in front of the building, and next to the truck was a tall and mighty Lincoln van.

Marven knows the truck driver and also came to deliver the experimental equipment two days ago.

Marven walked over and said hello to the driver who got out of the car, and then prepared to go to the back to unload.

At this moment, the door of the Lincoln van next to it opened, and a young man in a black T-shirt with a pair of black sunglasses on his face came down.

I walked up to the front and looked at it, and asked, "Are you Marven?"

As soon as Marven heard it, he knew that the "main master" was coming, nodded and said, "Well, I am Marven." Pls are you ......"

"Don't worry about who I am, go unload. ”

Marven responded and went to move the goods with four other colleagues.

There is a lot of equipment, and there are many large equipment, so I can only go to the forklift again.

After a lot of effort, all the equipment was finally transported to the upstairs research institute.

Everyone was busy disassembling the equipment.

Someone exclaimed, "Wow, EnvisionTEC's 3D bioprinter, these two systems are probably millions of dollars, right?

"What's more, look at this, Suofo's high-speed refrigerated floor centrifuge, Zeisen's inverted microscope, Nikon's optical microscope, Zeissen's scanning microscope. ”

"What's all the fuss about, you look at those thermostatic incubators, ovens, spectrophotometers, balances, PCR machines, decolorization shakers, which is not the best brand? ”

Chen Xu, who was wandering around the research institute, came over and said with a smile: "You work hard, boss, I'm not short of money......

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