Chapter 480: New Year's Gift

The time soon came to the thirtieth day of the lunar month, the day of family reunion, but on this day, the institute was still brightly lit, and everyone seemed to have forgotten what the New Year was.

Time is never wasted, and on this day, at the moment when the New Year's bell rang, there was a big news in the research room where Cheng Ran was.

A special protein sensitive to cobalt chromium was discovered, and this compound was extracted from KM mice.

The discovery process is also very simple, that is, modeling, modeling experimental animals such as KM mice, guinea pigs, rabbits, pigs, etc., requiring a certain amount of cobalt-chromium free substances to be injected into the body, but these cobalt-chromium free substances should be specially radiolabeled to observe the main behavior of these substances into the animal's body.

This is a method that Bai Ye came up with, although he has found these substances through [Deep Scan], it does not mean that he can clearly tell others.

Therefore, first of all, he put forward various hypotheses, and Bai Ye found through observation and analysis that the main attachment sites of cobalt chromium elements are still nerve cells, blood vessel walls, liver and kidneys.

When analyzing the screenshots, Bai Ye suddenly discovered a strange phenomenon, that is, how cobalt-chromium ions entered the white matter of the brain!

By comparing thousands of screenshots of different sizes, Bai Ye found an interesting thing, that is, on the cell membrane of vascular endothelial cells, there is a cobalt ion embedded in a protein channel, which is pure in free form and does not react with other substances.

This aroused Bai Ye's curiosity.

Continuing to look at other photos and information, this time, he found a magical secret, that is, how cobalt enters the neurons of the white matter of the brain through the blood-brain barrier!

Know that the blood-brain barrier is one of the strongest defense systems in the human body!

It is a barrier between plasma and brain cells formed by the capillary walls of the brain and glial cells, as well as between plasma and cerebrospinal fluid formed by the choroid plexus.

These barriers happen to prevent certain substances from entering the brain tissue from the bloodstream, and most of these substances are harmful substances, as if the human body has the function of recognizing harmful substances and can keep them out.

A variety of solutes in the blood enter the brain tissue from the cerebral capillaries, some are difficult and easy, some pass quickly, some are slow, and some are completely unable to pass, this selective permeability phenomenon makes people imagine that there may be a certain structure that restricts the passage of solutes, and this structure can make the brain tissue less or even not damaged by the harmful substances in the circulating blood, so as to maintain the basic stability of the environment in the brain tissue, which is of great biological significance for maintaining the normal physiological state of the central nervous system.

Therefore, when Bai Ye was observing how cobalt ions passed through this barrier, he suddenly discovered a mysterious protein!

The cell membrane has pathways, including some protein channels, and it is obvious that this cobalt element penetrates the blood-brain barrier through this protein, causing damage to neurons and some damage to myelin.

This discovery is crucial!

So he came up with an animal model to look for the protein, and since cobalt can pass through the blood-brain barrier in the human body, other animals will definitely exist as well.

To this end, Bai Ye asked the experimental team to increase the dosage of cobalt, even to the limit dosage and the maximum lethal amount.

As long as the animal does not die, it continues to increase the cobalt ions, hoping to increase this probability by observing the high concentration of the environment.

These people are professional researchers, they know a lot, and they are very fast.

During the experiment, a Sven man with eyes under Cheng Ran's experimental group and a tall classmate discovered a protein together, which has a certain affinity for cobalt ions, which is very rare, and is a special protein found in KM mice.

This made the two of them instantly excited!

This is definitely big news, and after getting the news, the two hurriedly reported it.

It's almost twelve o'clock, and in any corner of China, it's a happy welcome to the arrival of the New Year, but many rooms in the Bai Ye Research Institute are still brightly lit.

Of course, the vast majority of people are at home, and not many are in the lab.

Because Bai Ye's family was in the United States, he naturally did not return to the Puze family building for the New Year, Li Ziyan invited Bai Ye to go home for the New Year, but Bai Ye refused.

Because now is the critical time for the experiment, Bai Ye doesn't want to relax at this time, after all, there are still a bunch of people abroad waiting to see the joke!

Gao Yueyang received an invitation to go up to watch the Spring Festival Gala this year, and Liu Boli wanted to accompany the family, after all, he already needs to take care of himself at such an old age, and Cheng Ran is going to the Spring Festival Gala to receive commendation this year, as a leader in science and technology, the country has to commend some people every year.

Bai Ye was fortunate enough to go there, but because he went to Mai Country, he was taken by his mother.

Anyway, most of the experts, professors and academicians have gone home for the New Year at this time, and it is these young people who are staying in the institute, they have hard work and enterprising, and it is also a vision for the future.

Just like Chen Yu, a man with glasses, and Qin Yue, a tall man from his classmate, they are basically in experiments every day except for rest time.

Doing experiments is not done all the time, most of them are doing experiments - waiting for the results - doing experiments - new results.

The time spent waiting for the results is very fulfilling for them to consult the information.

When they reported the news to Bai Ye, Bai Ye went directly to their laboratory.

Seeing Bai Ye coming, the two of them spoke excitedly!

"Dean, we found a substance that is a special transporter on top of the cell membrane, his KM mice...... We found that he has a certain affinity and specificity with cobalt ions, which can make proteins and ions form a special state, so that cobalt ions can pass through the cell membrane and enter the organs. ”

Bai Ye's eyes lit up, and he hurriedly looked at the microscope, and sure enough, under the high-power field of view, a special form of cell membrane was discovered, and cobalt ions were specially labeled, so they could be found under the electron microscope!

Bai Ye's spirit suddenly perked up: "Where did you find it?"

Qin Yue said excitedly: "It was found on the microvessels of the kidney. ”

Bai Ye understood that the substance they had found on the blood vessel wall of the kidneys was exactly the same shape as the human body in the human body [Deep Scan].

Good news!

Definitely good news!

His discovery was confirmed by these two young people, and the more Bai Ye thought about it, the happier he felt.

At this time, the sky is gorgeous.

Bai Ye looked up, the New Year has arrived!