Chapter 348: A Nail Across the Ages

Absorbable bone nails are obtained, product properties: the initial bending strength of the material is 375a, the shear strength is 320a, the strength maintenance time is 1218 weeks, and it can be completely absorbed by the body within 3 years. Compared with traditional materials, the degradation rate and bone healing speed are matched, and the conductivity is excellent, which is conducive to bone healing.

Congratulations, get an absorbable bone nail, tips: this is an absorbable bone nail from BUIS company, the bone nail is the fourth generation of bone nail, the composition of a new synthetic biodegradable material, clinical advantages.

Hint, the material is a polymer material, polyKL lactic acid is the main raw material, in the human body can be decomposed into carbon dioxide and water, harmless to the human body, compared with the traditional bone nail, combined with the advantages of traditional titanium metal and polymeric lactic acid products absorbable advantages...... The advantages are obvious, and the study of this item requires: Materials Science Lv6, Orthopedic Energy Lv6, and Biomedical Chemistry Lv5.

The moment Bai Ye saw the nail, he naturally understood what it was!

After all, my own system is different from others, and it is a good system that serves the host with a conscience, well!

Naturally, what comes out can't be waste.

At present, the main material of the main absorbable bone nail is PLA material, and PLA material, as an orthopedic internal fixation material, has even innovated the traditional material, and can be said to be the world's most advanced orthopedic internal fixation material.

As we all know, the traditional fracture internal fixation materials are generally made of stainless steel, titanium and their alloys, but long-term implantation will cause erosion, allergies, osteoporosis due to stress occlusion, and fracture again after surgery, and most of them need to be removed twice.

In recent years, more fracture fixations made of absorbable materials have been used in clinical practice, and good internal fixation effects have been obtained.

The most clinically attractive advantage over metal fixation is that in cases of internal fixation of fractures with polymer biodegradable material devices, there is no need for a further removal operation after the fracture has healed.

Absorbable plates and nails are generally made of absorbable biodegradable material polylactic acid. Polylactic acid is non-toxic to the human body, and has good biocompatibility, and does not cause inflammation and foreign body rejection in surrounding tissues. Its degradation products are glycolic acid and lactic acid, which can participate in the carbohydrate metabolism cycle in the body, and after a series of biochemical reactions, it is finally degraded into carbon dioxide and water and excreted from the body.

No residue, no irritation to tissues, no toxic side effects. In addition, polylactic acid has good mechanical strength and elastic modulus, and the mechanical properties and degradation rate of polylactic acid can be adjusted and controlled by adjusting the molecular weight, selecting different polymerization methods and molding methods, so as to meet different clinical needs.

Moreover, what surprised Bai Ye the most was the several properties of this new material, such as the initial bending strength of the material, shear strength, etc.

Because the main function of these materials is the fracture end of the bone nail, these fixation materials are required to withstand strong strength and tensile resistance.

Although this PLA material is absorbable, these strengths are very insufficient, which is a very important drawback.

In the past, it was the weak mechanical properties of this resorbable biodegradable fixation that limited its widespread application.

In clinical application, polymer biodegradable materials must have physical properties such as considerable hardness, sufficient stability and final complete degradation in the human body, and can not produce any complications.

Over the years, through the continuous innovation and research of foreign researchers, the polymer biodegradable implantable device has met the above requirements and achieved the predetermined goals.

However, even so, the initial bending strength of the material is 175A, and the shear strength is 120A, but the strength of the nail in my hand has been more than doubled!

More than twice as much power as most of today's alloys.

As for the degradation rate, in fact, the faster the better, the degradation rate of 1218 weeks and the resorbable period of three years are perfectly in line with human fracture recovery.

When the fractured bone segment is completely healed, it begins to disintegrate and absorb in the body.

This degradation rate not only ensures the good in-situ healing of the bone segment, but also avoids the stress shielding effect in the later stage of bone healing, which is conducive to the reconstruction of the late stage of bone healing.

It can not only promote the healing and reconstruction of bones, but also decompose and discharge from the body after healing, avoiding the adverse reactions that may occur if the implant remains in the body for a long time.

Because it has been certified by the US FDA, it has been widely used in clinical treatment.

Although it is a little embarrassing, I have to admit that all the materials such as bone needles, bone nails, orthopedic fixation plates, etc. used in our country are imported!

That's right, all of them!

Because of the great lag in the development of our domestic PLA synthesis technology, the synthesis technology has not been made a breakthrough, especially the lack of high-purity chiral monomer preparation technology, resulting in the industrialization of PLA orthopedic products.

Of course, it does not mean that PLA materials are perfect, it can only be said that compared with the previous materials, there are a lot of improvements.

At present, the shortcomings of PLA material as an orthopedic internal fixation material are as follows:

1: It does not have bone conductivity, the speed of repair of bone defects is very slow, and it is difficult to achieve complete bone repair for large bone defects.

2: The mechanical strength of the material is not enough to be used as a fracture internal fixation material at the load-bearing site.

3: The early biodegradation rate is relatively fast, so that it cannot be guaranteed to meet the mechanical property requirements before the growth of new bone tissue, and the degradation rate in the medium stage is too slow, so that there are still residues left in the body after the growth of new bone tissue, resulting in complications.

Therefore, the nail obtained by Bai Ye is completely an evolved version of modern orthopedic internal fixation materials!

Bai Ye remembered that when reading the paper, many leading experts in Japan found that in fact, PLA materials are carcinogenic, and the experimental incidence is as high as 44, but some scholars question their experimental design, so this problem remains to be observed for a long time.

However, this also shows his shortcomings!

Therefore, when Bai Ye saw this nail, his heart jumped for no reason.

This is not just a nail, not just a product, this is a new era!

Bai Ye felt that if this absorbable bone nail could be developed and the material could be studied, it could be used as an orthopedic internal fixation material.

Moreover, this material can be used well in too many aspects and fields.

Once this is done, it is a future, an infinite future!

Thinking of this, Bai Ye was a little excited.

After all, we can research and produce world-leading orthopedic materials ourselves.

Bai Ye is confident that what he can do is to open up a new era.

Carefully putting away the bone nails, Bai Ye thought about it.

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To be honest, Bai Ye found a problem, that is, he found more and more that with the improvement of the skill level of the discipline, he found that the supporting facilities around him were becoming more and more unable to catch up.

He even felt that if he wanted to further improve the level of discipline skills, medical materials, medical equipment, medical drugs, etc. were all very important and critical things.

If you think about it, it's a very intuitive question.

For example, what kind of gap will there be between an orthopedic surgeon 30 years ago and an orthopedic doctor of the same level now?

The difference is a lot, because with the development of science and technology, ideas are constantly updated.

In the past, there were few CT and MRI machines in China, but now with the help of these auxiliary tools, many incurable diseases have been discovered and treated.

That's progress!

Therefore, medicine, whether it is Chinese medicine or Western medicine, is actually a discipline that treats diseases and saves people.

Their ultimate goal will all be to serve humanity.

Thinking of this, Bai Ye smiled gratefully at the virtual screen.

If it weren't for him, maybe he would just be an ordinary person!

When he returned to China, the first thing Bai Ye had to do was to improve the talent allocation of the scientific research institute.

No!

Now we have to start researching, maybe tomorrow I can have a job fair in Los Angeles!

Thinking of this, Bai Ye felt that this matter was very feasible.

After all, I just cured your Los Angeles heroes, and in Lao Bai's words, he is now a popular figure and a figure standing on the cusp of public opinion.

And Los Angeles is also a great place to be!

The location of California Polytechnic University, as a world-renowned private research university, is small but has a long-standing reputation in the world's scientific and technological circles.

Its dominant disciplines are physics and chemistry, astronomy and space science, and it is also an international leader in materials science.

Although the school is very small, with only more than 2,000 students, there have been 36 Nobel Prize winners in history!

What a scary number!

Moreover, it has the highest density of Nobel Prize-winning institutions in the world.

Therefore, if Bai Ye returned empty-handed, he would not forgive himself.

Thinking of this, Bai Ye felt that it was necessary to talk to Mr. Wynne about this matter tomorrow.

Maybe tomorrow I can bring back a top-level talent of material science, but I am hungry for talents now.

Bai Ye of the Institute of Orthopedics does not plan to do it as an ordinary hospital, he wants to treat this institute as an authoritative base for orthopedics in the world.

This is not only the research and treatment, but also any product in the field of orthopedics, I have the final say!

That's authority!

It is the world's highest level in the fields of academics, medical standards, medical drugs, medical equipment, medical talents, etc.!

As a distinguished member of life, Bai Ye felt that his courage should be magnified.

ps: Veterans feel like they can grow a little longer...... I decided that I could write more big chapters in the future, so that it would be more comfortable to read, how do you feel?