Chapter Seventy-Eight: Thesis in Preparation
After finding that molecule, Bai Ye turned on the computer and connected to the laboratory's proprietary database.
This is a small molecule compound with a very low content and a very simple molecular structure, but when this molecule acts with artemisinin, it is often highly effective and stable!
The results of statistical data analysis show that if other influencing factors are isolated alone, this molecule is effective in treating malaria when it is combined with artemisinin.
But what exactly is this molecule and why does it play such a role, Bai Ye is a little puzzled!
Didn't they find this thing?
It is very likely that Bai Ye synthesized all the relevant data analysis within fifteen years, and then found the balance point through that flash of inspiration!
And then I found this kind of molecule.
Nobel laureate Joseph Goldstein once said:
"The development of biomedicine is mainly through two different paths, one is discovery, and the other is invention. ”
Bai Ye knew that after continuous calculation and verification, he had discovered this thing, of course, this thing was probably meaningless, and this was the work you were going to do next.
Check it out!
Bai Ye frantically consulted the literature in the past two days, carefully studying everything related to this molecule, and even the things that extend from this molecule were carefully studied.
Two days passed in the blink of an eye, Bai Ye cleaned himself up, and then went to the dinner and salon.
In this salon, no one was underestimating Bai Ye, on the contrary, everyone was looking forward to what kind of questions this young man could ask.
Bai Ye cherishes and attaches great importance to the opportunity to discuss with everyone, these people are all seniors, and Bai Ye directly opened ten times the experience.
He didn't feel distressed, there was only one month here, and how much he could learn was up to him in the final analysis, and half a month had passed in the blink of an eye, and Bai Ye felt the urgency of time more and more.
Bai Ye listened to everyone's chat, as if he was listening to an academic report, these are all rich knowledge, and they are also naked experience!
He was very clever this time, he held a small book, and whenever he heard something very important or inspired, he immediately wrote it down and waited to consult it when he returned.
This exchange is no longer confined to biochemistry, but more broad, such as physiology, cell biology and other subtle perspectives, they explore intracellular functions in simple terms.
For example, changes in cell membrane permeability, and mitochondrial function, etc.
Intentionally or unintentionally, everyone talked about it relatively basically, and occasionally handed Bai Ye a kind look.
After three hours, everyone slowly fell silent, and suddenly Karis asked, "Bai Ye, do you have anything you want to publish?"
Karis didn't say that you don't understand anything that you need to ask, but what he said was whether he had any opinions, although the meaning was not much different, but it showed his fair recognition of Bai Ye, there is no high or low academics, they are equal.
Even the simplest 1+1 and complex Goldbach conjecture. They are all academic discussions.
Bai Ye thought about it, so he brought this molecule out.
Karis was clearly familiar with the molecule: "This molecule should have no meaning, and it is very easy to separate, and it is found in many compounds, like water molecules, and I really can't find its meaning." And ......"
At this time, a black girl took over the topic: "Well, when I was doing reagent stability experiments, I saw this thing, and I haven't paid much attention to it, because many experiments have also analyzed this molecule, and it doesn't make a lot of sense." ”
Everyone shared their knowledge about this molecule.
And Bai Ye also recorded it carefully, this knowledge is very useful, and it directly opened a door for Bai Ye to analyze an item from physiological and biochemical, physical and chemical factors, drug metabolism, human reaction, drug purification, compound pairing, and so on.
After it was over, Bai Ye heard the system's prompt sound.
"Ding!Pharmacology skills have been upgraded to lv4!" Bai Ye was overjoyed, pharmacology had actually improved!
Indeed, because this lesson is mainly about the various properties of drugs and metabolism and so on.
After sharing, Bai Ye was still unsatisfied, but everyone was really tired, Bai Ye got up and smiled thankfully at everyone, and everyone responded kindly.
For such a little junior brother, everyone likes to carry it very much, and the speed of progress of this little junior brother is really a bit fast.
Just as he was leaving, Karis suddenly stood up and said to Bai Ye: "This week, I have other things, you don't have to record data for me." ”
Bai Ye was stunned for a moment, a little regretful, because Caris usually taught him a lot of things.
Seeing Bai Ye's expression, Karis continued: "Haha! I may have to follow Professor Tu back to Denmark to attend a conference in the next half a month, of course, you can use my instruments!"
Bai Ye's eyes suddenly lit up, can he use the instrument?
Here's your chance!
He had an idea about this molecule, what exactly did he do with artemisinin?
Bai Ye wanted to find out.
In the next week, Bai Ye took a leave of absence with others and concentrated on the first group.
The others didn't arrange a job for Bai Ye, because they all knew that Bai Ye had recently made his own discovery.
That's a good thing!
It's good for scientists to have an idea, at least you can start validating your idea.
According to the knowledge he learned, Bai Ye separated artemisinin from physical and chemical properties, and then purified and extracted it, which was very basic.
Bai Ye did it for two days, and he was finally able to operate it perfectly.
In the following time, Bai Ye tried to add this molecule to artemisinin, but the two were not compatible at all, so he consulted all the people in the first group, and they made a lot of suggestions, such as considering using physical factors to fuse under the microscope.
It's just that...... This is too high for the operator, and it is difficult for Bai Ye to meet it, so Bai Ye tests it day and night.
Moreover, Bai Ye found that it was still difficult for these two molecules to fuse, so ...... How can we achieve communion without affecting their molecular structure?
Bai Ye was very bright this time, and thought of the means of concocting traditional Chinese medicine.
As early as the Eastern Jin Dynasty, Ge Hong's "Elbow Reserve Emergency Prescription" wrote: "Hold the Artemisia annua, stain it with two liters of water, wring the juice, and serve it!"
Bai Ye was stunned!
Instead of traditional boiling, the ground juice is chosen, is it because the high temperature will destroy the activity in it?
So when Bai Ye obtained artemisinin this time, he chose other ways.
Finally, on the sixth day, Bai Ye finally obtained the substance in which molecules and artemisinin coexisted.
Bai Ye is named: stable artemisinin complex.
In the evening of the same day, Bai Ye wrote out the paper, and retrospectively analyzed the data analysis from 2001 to 2015 and the clinical efficacy of stable artemisinin complexes.
The title is: "A Retrospective Study of the Efficacy and Safety of Stable Artemisinin Complexes".
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