Chapter 570: Found You! Something to Chase the Culprit!
[Deep Scan] is a very buggy aid.
In the past year, Bai Ye has never been willing to use it, but today, Bai Ye still decided to take it out.
Selecting [magnification], the bacteria on the glass slide in front of him began to be magnified crazily, and the NBOD-31 bacteria, which could not be seen clearly even under the electron microscope, appeared very large at this time, and suddenly, Bai Ye seemed to be in a huge strange biosphere.
The wriggling flora in front of you is the mainstream of this world, and they are constantly moving, frantically transporting in the petri dish.
Bai Ye first observed the cell wall of the NBOD colony, which is a magical cell wall composed of glycogen, which can even block the high temperature of more than 80 degrees Celsius, so that he is safe and sound.
It's how he survives.
After Bai Ye compared, he found that there was no difference in the cell wall.
Subsequently, Bai Ye transparentized the entire cell wall.
The cell membrane begins to appear, and the cell membrane is not unusual, as beautiful as ever, or it is like a hive, with a large number of carrier proteins engraved on it, allowing those cells to selectively secrete some substances to the outside of the bacteria.
Time passed minute by minute, and Bai Ye suddenly felt that all this seemed very charming.
Provided, of course, that you don't have a phobia of intensity.
Cell membranes, continue to be transparent!
At every step, Bai Ye carefully took screenshots, he was reluctant to let this only [Deep Scan] go down the drain, in case there was nothing to gain, he could stay and study this one bacterium.
Plasmid studies contain more than 130 genes in plasmids that can transcribe bacterial genes.
All this was hidden in front of Bai Ye.
Plasmid comparison...... Unanimous!
Plasmid gene sequence...... Unanimous!
Comparison ...... Unanimous!
Comparison of intranucleometric genes...... Unanimous!
What's the problem?
Is there any difference between them before and after?
At this time, Bai Ye used [Inspiration]!
At the moment when the inspiration started, the countless pictures that had just appeared in Bai Ye's mind began to reorganize, and these large numbers of pictures and photos were even quickly linked, looking for a breakthrough!
Bai Ye's mind is like a supercomputer!
Suddenly, Bai Ye's eyes lit up, he found the difference, although it was very subtle, but he finally found it!
Unexpectedly, I really didn't expect that there is a very hidden ribosome on the cell membrane of this flora!
I didn't expect this bacterium to have two ribosomes!
This is a bit beyond Bai Ye's imagination.
There is only one ribosome in the normal NBOD-31 microflora, but after the mutation, there is a ribosome with special properties hidden under the cell membrane, or even in the substance like a "beehive" hidden on the cell membrane!
That's where the mutation lies!
What's the difference?
Bai Ye faintly felt that this should be the mutation, and this should have a lot to do with the occurrence of bowel cancer.
What the hell is it!
Ribosomes are structurally different from other organelles, they are not membrane-coated, they are composed of two subunits, they can attach to the endoplasmic reticulum or be free of the cytoplasm because of their functional needs, and ribosomes are sometimes not considered to be a class of organelles, but rather intracellular macromolecules.
So at the beginning, Bai Ye easily thought that this was a substance on the cell membrane.
Ribosomes are responsible for the "central law" of moving from RNA to protein in the cell, a process known as "translation" in biology.
Before translation, the small subunit of ribosomal conjugates to the messenger RNA transcribed from the nucleus, and then binds to the large subunit of the ribosomal to form a complete ribosome, which can be used to synthesize peptides using amino acid molecules transported by transport RNA in the cytoplasmic matrix.
When the ribosome completes the translation of a single strand of mRNA, the large and small subunits are separated again.
So its only function is to synthesize amino acids into protein polypeptide chains according to the instructions of mRNA, so ribosomes are molecular machines for protein synthesis in cells.
Anyone who has been in high school biology knows that this is the so-called protein processing plant.
Because there are no mitochondria in bacteria, there are only ribosomes from such a secondary processing plant.
Transparent ribosomes, Bai Ye finally saw where the mutation was.
At this time, Bai Ye happened to see that the processing plant of this "pseudoribosome" was forming a polypeptide chain to form proteins...... This is a new substance.
What is this substance?
What are the benefits?
This has become a major factor and breakthrough point for the breakthrough of bowel cancer.
However, this substance is not secreted, but attaches to the cell wall, as if adding a new weapon to the cell wall, which seems to retreat and attack.
Although it looks the same as the original NBOD-31, it is almost identical, but if you look closely, you can still see the difference.
The main thing is the difference in chemical structure!
The functions of the bacterial cell wall include: maintaining the cell shape and improving mechanical strength, inhibiting mechanical and osmotic damage (the cell wall of gram-positive bacteria can tolerate pressure of 20 kg/cm2), mediating cell-cell interactions (invasion of the host), preventing invasion of macromolecules, and assisting in cell motility and growth, division and flagellar movement.
The thickness of the cell wall varies from bacteria to bacteria, but is generally 15-30 nm.
The main component is peptidoglycan, which is composed of N-acetylglucosamine and N-acetylmuramic acid to form a disaccharide unit, which is linked into a macromolecule by a -1,4 glycosidic bond. There are tetrapeptide side chains on the N-acetyl muramic acid molecule, and the short peptides between the adjacent glycan fibers are bridged by peptide bridges (gram-positive bacteria) or peptide bonds (gram-negative bacteria) to form peptidoglycan sheets, which are bonded into multiple layers like plywood.
In this way, the combination of multiple layers can make the cell wall have more efficacy.
And this new substance is on the surface of the cell wall, forming a new layer, this layer, is very unusual!
Although it is only this layer, it is because of this simple layer that this flora has undergone major mutations.
Turned into two different substances!
[Deep Scan - End!]
Bai Ye closed his eyes, this time, he gained a lot!
The next time is to extract these cell walls and then experiment in animals to see if there are any gaps.
The isolated cell wall was ready-made, and Bai Ye directly arranged for the experimental group to conduct the experiment, and this time, Bai Ye was not acting alone.
Unexpectedly, a week later, a report came from the experimental group!
This cell wall can act directly on intestinal epithelial cells to form cancer cells.
Bai Ye's eyes suddenly lit up!
The answer has been found!
Finally found you, this thing that has puzzled the culprit for a long, long time, it turns out that you are hiding here.