The news of Naya Group instantly spread in China and caused a heated discussion.

At this moment, everyone was talking about this move of the Naya Group.

"I'm going? True, Naya Group has launched a new type of SHR? No, it can't be called SHR, it should be called a new type of essential hypertension mouse!"

"Haha, really, if it's true, if it's true, then you don't have to be angry, that group of capitalists from dog X, let you scream. "Even the well-educated scientists of the past are happy to swear.

"Support Naya, support domestic production!"

Whether it's true or not, Naya's announcement really boosted everyone's popularity!

………………

But while everyone was talking, Macalet, an expert in the European gene bank, was sitting in his office. Holding a cup of coffee in his hand, he said with a smile: "Bonnt, don't worry, if the new SHR is really that easy, the group of Chinese will not order so much." ”

Burnt looked at the computer in silence, not knowing what he was thinking, he always felt that things were a little strange.

Tang Han he understands, Naya Group and Longka are competitors for a day or two, if it is said that it is not necessarily your friend who knows you best, it is likely to be your opponent, this sentence Bont agrees very much.

He felt that Tang Han was not the kind of person who bluffed at all, that man was very courageous, or he didn't do it, and he would definitely have to go all out if he wanted to do it.

Naya officially launched this announcement, and it must have been authorized by Tang Han.

In this case, this matter needs to be further investigated.

Thinking of this, he called the person in charge of the Asian region: "You pay close attention to Naya's dynamics, please tell me immediately if you have any news." ”

Macalet sniffed the fragrant coffee, and he scoffed a little at Boonte's caution.

If the new model of essential hypertension is so simple, it will not be that they have been working hard for so many years and still making slow progress.

"Burnt, I don't think what you should do now is to be cautious about Naya, but to defeat this lie! ”

Bonntt smiled: "I naturally believe in Mr. Wright's ability, in the field of genetic engineering, you may be the most professional, I will go and release new news now, in a month the number of SHR sales in Asia will be limited." ”

………………

After Zhang Hanlin saw Naya's announcement, he hurriedly dialed Tang Han's phone, and now the two communicate frequently.

"Mr. Tang, has your company really researched a new type of essential hypertension mouse?" Zhang Hanlin was still a little unconvinced.

Tang Han smiled: "Well, if there is no big problem, it may be true!"

When Zhang Hanlin heard Tang Han's personal confirmation, he also felt as if he was encouraged!

"Beautiful!

Tang Han suddenly asked, "Aren't you surprised who did this?"

Zhang Hanlin was stunned: "Who is doing something different? Naya Group is full of talents, I believe there are always geniuses!"

Tang Han laughed: "It was studied by Bai Ye." ”

After hearing this, Zhang Hanlin let out a faint sigh and asked, "Bai Ye went to you?"

Tang Han was a little confused: "Aren't you surprised?"

Zhang Hanlin: "Surprised? If someone else did it, I might be surprised, but ...... Bai Ye's words should have been used to it, otherwise I would have had a heart attack. Now that you tell me that Bai Ye has been nominated for the Nobel Prize, my heart will not fluctuate in the slightest. How do you say that?

……………………

……………………

Just when everyone was paying attention to the news of essential hypertension mice, Bai Ye finally wrote a paper on the unstable genes of KM mice.

The name is: "For those past experiments, the real culprit of clinical trial death is actually - unstable guanine"

He restored all the experimental data, and to be on the safe side, he also backed up several copies of the data.

The gene of this stable KM mouse did not change much to remove the guanine, and Bai Ye tried to remove the guanine base in the nucleic acid of embryonic cells during this time.

However, this is no longer possible for him to do, because it is difficult for the base contained in the mouse embryo to change further without a reaction.

Just like a defense mechanism, this base will only exert its role when a series of reactions occur.

Bai Ye exchanged the news with Dong Cunguang, but he also frowned and tightened, there was nothing he could do.

What to do?

Experts in the field of genetic engineering don't know much about themselves, right!

This is a big coffee who graduated from a world-class school, maybe she will have a way, right?

After Bai Ye called Zhang Shulan, he told her what he had discovered, Zhang Shulan was silent for a while, and suddenly said: "You come to the Institute of Bioengineering of the Chinese Academy of Sciences, I will wait for you in the office." ”

After Zhang Shulan hung up the phone, although her words were calm, her heart was like a volcanic eruption under the sea!

The news that Bai Ye brought to him was too shocking, KM mice are recognized by the world as extremely stable and most suitable for human research and experiments.

But can this view be proven wrong?

If it's true......

The consequences are unimaginable, and this is not only a problem for mice, but if it is proved that the instability of KM mice does exist, then many previous experiments have failed...... There are still so many drugs on the market that have problems...... It's all explained.

So after understanding this problem, Zhang Shulan directly asked Bai Ye to come to the office, Bai Ye was not in a hurry, but she was restless.

After Bai Ye arrived, the two of them closed the door directly, and Bai Ye had already opened the prepared notebook, and all the data was recorded inside.

Zhang Shulan looked at the analysis results of the data and experiments seriously, holding a piece of paper in her hand, and kept writing and drawing, hoping that Bai Ye had a problem in that link.

To be honest, she didn't want Bai Ye's conclusion to be true.

Because if this is true, it is very likely that the medical market will face a huge upheaval for a long time to come, which is not a good thing, and the panic of people's emotions is also a disaster.

But after reading most of them, Zhang Shulan sighed, it's okay...... This genetic instability occurs only in rare cases and is not easily triggered.

Zhang Shulan looked at Bai Ye and was a little curious: "How did you come up with the idea of studying this?"

Bai Ye said: "This involves the research of a new drug in the past, and I published a paper in the journal "Cell" ......."

After Bai Ye told Ke Ao about it, Zhang Shulan's eyes widened and she suddenly said:

"You're talking about the Mikasu-Tranri incident?"

Bai Ye was stunned: "Teacher Zhang, do you know?"

Zhang Shulan sighed: "Mikasu is the person who was nominated for the Nobel Prize, if he didn't have that thing, it is likely that the next Nobel Prize winner will be him, but unfortunately, as a top celebrity in the field of microbiology in the world, his research on microorganisms is definitely not comparable to others." ”

"When I was doing research at Johns Hopkins, I heard that Dr. Mikasu had invented a drug that could inhibit the expansion of tumor cells through the study of a certain microbial single cell. ”

At that time, the experiment attracted the attention of countless people, as a star experiment abroad at that time, scientific research funding sponsorship reached 1.2 billion US dollars, all experimental data and experimental equipment, participants are the top existence in various industries, after the success of the first phase of animal experiments, major institutions, pharmaceutical companies have made sky-high commitments, but also in the follow-up clinical trials to prepare nearly 2 billion reserves. ”

"Even Nature, Science, and even Time were ready to put Dr. Mikasu Tranry on the cover, just waiting for the results of his clinical trials!"

"It's a pity...... In the first phase of the clinical trial, all the experimenters involved in it accelerated their deaths, and instead of inhibiting the growth of tumor cells, they inhibited the growth and development of normal cells in the human body......"

Speaking of this, Zhang Shulan sighed: "In the following years, they have been exploring the cause, but unfortunately they have not found any reason, and Dr. Mikasu suffered from severe anxiety and depression under the pressure of public opinion and self-condemnation, and committed suicide in the laboratory. ”

The room fell silent all of a sudden, and Bai Ye finally understood the whole story, it turned out that this incident was so famous.

Zhang Shulan said regretfully: "I also participated in Dr. Mikasu's lecture at that time, and it was really the greatest person in the field of microbial engineering. His death is a great loss to the entire field of human bioengineering. ”

Speaking of this, Zhang Shulan suddenly looked at Bai Ye with a complicated expression: "If only you could be born a few years earlier, maybe...... He didn't have to die. He's only 59 years old and he's accomplished so much......"

In the next few days, Bai Ye and Zhang Shulan restored the experiment from beginning to end about the unstable gene, and still got this unstable base.

Zhang Shulan looked at Bai Ye and said, "Where are you going to send this article?"

Bai Ye shook his head: "I haven't thought about it yet, maybe it's MIO, because this is also an article in the field of laboratory animals." But "Cell" is fine, after all, Coo is the editor-in-chief there, and it may be more appropriate for him to publish this article, at least let him ......"

Zhang Shulan was suddenly stunned for a moment and asked, "Why don't you post it on the "Journal of the Chinese Academy of Sciences"?"

Bai Ye: "Huh?"

Zhang Shulan suddenly blushed: "You are also a graduate student of our academician of the Chinese Academy of Sciences, what's wrong with publishing it in our academy newspaper......

"The Journal of the Chinese Academy of Sciences is also SCI level, but the impact factor is relatively low, in fact, our level is there, mainly because the international influence is poor, if your article is published on it, maybe you can improve his international status......"

Bai Ye was stunned for a moment, and asked embarrassedly, "Is this okay?"

Zhang Shulan also smiled: "In fact, it is the same everywhere, the focus is to spread the news, this is the most important thing, isn't it?"

"Besides...... You now have an impact factor of 258 points, which is better than many mentors, and there is no shortage of this article, right?"

…………………………

Bai Ye called Keao that day.

"Hey, Bai Ye, can you consider the problem of jet lag next time you call? It's 3 o'clock in the morning now. Keo said helplessly.

Where did Bai Ye still think about this question at this time: "Keao, if I tell you now that I find out the reason for your teacher's failure, will you think that I disturb your sleep?"

Suddenly, there was a moment of silence on the other side of the phone: "This joke is not funny......"

Bai Ye smiled: "What I said is true, I really calculated it, the failure of the whole experiment has nothing to do with your teacher." ”

Keo was stunned: "Is what you said true?"

Bai Ye nodded: "Maybe you can come to the Chinese Academy of Sciences in Kyoto, I have a detailed experimental process here." ”

The next afternoon, Ke Ao arrived, and as soon as they met, Ke Ao walked towards Bai Ye with red eyes: "Are you sure what you said on the phone is true?"

Bai Ye nodded: "Come with me, I'll take you to prove it in person." ”

Bai Ye took Keao and Zhang Shulan, and the three of them restored the experiment again, and after seeing the results of the experiment, Keao howled and cried.

A big man of more than 1.8 meters cried like a child, and Zhang Shulan was also a little unbearable.

Three days later, the Journal of the Chinese Academy of Sciences published a special issue, the cover of which was not Bai Ye, but the head of Dr. Mikasu Tranry.

There's a title on the cover:

"For those experiments in the past, the real culprit of clinical trial deaths is actually - unstable guanine"

The influence of the Bulletin of the Chinese Academy of Sciences is still there, especially in Asia, after all, the technical content is still very high.

Therefore, the special issue has just been published, which has aroused heated discussions among many people.

"It's impossible, right? We have used KM mice for so many years, and there is a problem?"

"Generally speaking, there will be no problem, don't you see what it says? Only under special conditions will there be a trace of mutation. ”

"But...... It's terrifying, too!"

"It turns out that Dr. Mikasu's death turned out to be because of rats!"

"Oh my God, is this true? It's unbelievable. ”

For a while, in the entire field of scientific research, many people who paid attention to bioengineering information saw the information of this weekly magazine and immediately discussed it.

The news was so shocking that everyone had to doubt his reliability.

It is terrible that the KM mouse that people have used for so many years turned out to be an unstable mouse, and it may even be different from the human body.

Moreover, not only these bystanders, but also many examples of scientific research failures began to reflect on whether they used KM mice in the first place, and how much influence the mice had on their experiments.