Chapter 154: The Strategy of Breaking Up into Pieces

The cross-cutting development of top disciplines in multiple fields, as well as the sponsorship of top biomedical groups, put MIO in a good virtuous circle.

At this time, in the research center of the MIO Research Institute, Enders was flushed and calmed down.

Since receiving the article "BPFH Grading System for Experimental Mice" from Bai Ye in China, this is the fourth meeting, and the debate is very lively or very hot every time.

The meeting was attended by more than 20 related project teams under the MIO Institute.

As the most authoritative organization in the field of laboratory animals, MIO has set up a special scientific research team for each index and field of laboratory animals, in order to achieve specialized personnel engaged in specialized work.

In this way, it is possible to develop together with multiple disciplines, and some can be integrated into an all-round development.

Today's meeting is also aimed at Bai Ye's "BPFH Grading System for Experimental Mice".

As the chief engineer in charge of animal experiments at Johnson & Johnson, Enders has long seen the good performance of this article, especially the proposal of the BPFH score, which can be said to be a great score in the entire field of animal experiments.

Enders took a deep breath and continued, "Guys, today we are here to come to a better conclusion, not to argue. I really think the ideas presented in this article are worth looking into. ”

At this time, a white man in his 50s had a stern face, his thick eyebrows were frowned together, and he said solemnly: "Enders, I think you are a little too exaggerated, do you know how much work it will take to verify all the items on the score sheet?"

"It's going to take more than 20 of us to experiment at the same time, to abandon all the research we're working on, and instead evaluate these scores, which are probably meaningless, and it takes seven days, you know what that is?"

"Let's be realistic, it's not a small number to afford, do you think those pharmaceutical groups have so much money? They're just a bunch of vampires, where do they have the extra money to do this ridiculous rating test?"

Enders was a little annoyed, this white man Makota was simply selfish and didn't look like a scientific researcher!

However, the MIO is a democratic and free institution, and there is no dictatorship, but Enders, as the chairman, has the privilege of the chairman, although this privilege is limited to the number of times.

However, he was very interested in Bai Ye's BPFH score, which opened a new era of experimental mouse research, and once successful, it was undoubtedly a milestone in the development of mouse research.

After a half-silence, Enders raised his head, his eyes were like torches, and said word by word: "I have decided, all groups, to suspend all current projects, conduct a systematic evaluation of the BPFH score, and test the reliability of the BPFH Rating System for Experimental Mice." ”

Karta was stunned!

His eyes widened and he said, "Enders, you're messing around, do you know what you're talking about?

Enders snorted: "Oh? Of course I know, have you been working on the research on matched stable mice? Hehe, how many years have it been? Has there been any results? Mice that match the genetic stability of the human body, have you been more than five years? Are you still stuck at that point and can't move forward? So a pause for a week shouldn't have an impact, right? Maybe you can save a little money." ”

"Okay, you don't need to say, I use the privilege of the chairman of the MIO once, and from now on, suspend the current research and verify the "BPFH Grading System for Experimental Mice"!"

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Bai Ye frowned and looked at the data records in the notebook, these were all perfected, but Bai Ye had a different idea in his heart.

Now he knew why they had failed, but how could he prove it?

How to prove the unique adaptability of KM mice, so that the genetic sequence of mice is mutated, resulting in a series of erroneous conclusions.

In fact, the drug does not inhibit the reproduction of tumor cells, but mutates one of the purines in the DNA and RNA sequences of mice in transcription and translation, resulting in a series of evolution-like adaptive changes, and a wrong conclusion is reached.

Bai Ye felt that a series of experiments should be conducted to prove the stability of the gene sequence of KM mice.

If it is proved that a certain gene sequence in KM mice is not stable, it can lead to variation and specific adaptations under certain conditions.

This variant makes mice unsuitable for animal experimentation because they are so different from humans that the conclusions from the experiments are not applicable to humans.

Therefore, these KM mice are not fully suitable for animal experiments on human drugs!

But how do you do such an experiment?

This is not a simple control group experiment, it involves the problem of genetic engineering, and once it involves genetic engineering, this topic cannot be solved with millions of dollars.

Because those genetic engineering instruments are very expensive, and the cost of the experiment is very high, not to mention Bai Ye, even the current Jinxi University of Traditional Chinese Medicine does not have such experimental conditions.

Is it just dragging on?

Bai Ye was a little unwilling, hey...... If only we had our own lab!

Thinking of this, Bai Ye was full of infinite fantasies about his 500-square-meter laboratory.

It's a pity, 5 million~ terrible!

Isn't it five million? Bai Ye is confident that when the feed is researched, these five million is not a big deal at all!

There have been too many messy things recently, Bai Ye is a bit messy, and he can't take over so many things in the future, otherwise he really won't have enough energy.

Further genetic testing research in KM mice has been temporarily stalled.

Next, let's get the feed thing done, and when the "BPFH Grading System for Experimental Mice" is released, it will be a storm in the laboratory animal world, and when the time comes, you will definitely be able to push the BY-1 feed abroad!

Let foreigners also feel a handful of the traditional core technology of our big China.

We raise rats...... In fact, it can be very professional.

Thinking of this, Bai Ye's thinking is also clear, and the current direction of work is also clear.

The subject still has to be done, but not to do BPFH scoring, but to be specific to each small step, and specifically to do the control.

For example, the determination of a specific item of experimental stability in mice in the BPFH score is also possible!

That is, to separate the indicators in the BPFH score and do it separately!

Bai Ye's BY-1 feed was compared with the imported feed on the market to see which effect was better.

This is also a problem!

When the "BPFH Grading System for Experimental Mice" is released, I can synthesize these data by manipulatively, and the synthesis is not the so-called BPFH score?

Besides, he is the inventor of this score, so he naturally verified that his feed can effectively improve the score of BPFH.