Chapter Eighty-Five: People Open the ...... by Strength
Traditional Chinese medicine focuses on syndrome differentiation and treatment, rather than sticking to a certain drug.
This is a scientific research institute, Tu You is from the Institute of Traditional Chinese Medicine, how can there be no traditional Chinese medicine here?
Bai Ye followed the ancient prescription and found the corresponding Chinese medicine.
Beginning experiments over and over again, he first boiled the Chinese medicine and went to find the active ingredients in it.
But at the beginning, Bai Ye encountered a problem!
With so many compounds, how do you determine what the active ingredient is?
In fact, Bai Ye now has a feeling that traditional Chinese medicine is a golden mountain, but modern technology is like an axe.
I knew that there were many precious things in this golden mountain, but I couldn't take them out, and I was powerless.
You can only go to the soft places that are easy to dig to dig for gold.
Perhaps one day, modern technology will reach the point where it will be enough to dissolve this mountain of gold and move it piece by piece.
It's this treasure trove that truly shocks!
Bai Ye first injected the decoction into artemisinin-resistant rats, but ...... The effect is average!
As a result, Bai Ye was indeed a little embarrassed, and he was busy with a lot of work, but he didn't expect that the guess was wrong!
So where do you start?
Changing the structure of artemisinin, creating new artemisinin, but the experimental team has done too much.
It's too hard, it's too hard!
What to do?
Bai Ye was a little weak.
Maybe that high-level mission won't be completed at all!
Not to mention the ultimate mission.
Bai Ye sighed, a little relaxed.
Just when Bai Ye was speechless, he suddenly remembered the book he had obtained, "Processing Experience and Grade Classification of Traditional Chinese Medicine".
After Bai Ye opened it, he searched for it, because at that time he remembered that there were only 45 common Chinese medicines in it, modern research and grade classification.
Bai Ye wasn't sure if there was Artemisia annua in it.
After opening it, Bai Ye actually had a lot of expectations in his heart, and he slowly opened the catalog:
"Licorice...... Bupleurum...... Codonopsis ...... Chinese wolfberry...... Artemisia annua!"
Got it!
Sure enough, there is!
This is a handbook of traditional Chinese medicine two hundred years later, which records the processing methods and research progress of traditional Chinese medicine.
Bai Ye turned to that page with anticipation and began to read it.
"Artemisia annua, a traditional Chinese medicine, is a plant of the Asteraceae family...... It has the ...... of clear and hypothermia, cooling blood and removing steaming, relieving heat and intercepting malaria."
Bai Ye understood these things, and even he knew that Artemisia annua was taken from its leaves before flowering, because this way the most artemisinin was obtained.
Next is the grading of artemisinin Chinese herbal medicines, and the preservation and processing of Chinese medicines.
These are not what Bai Ye is looking for, what he is looking for is the research progress of modern medicine!
Bai Ye continued to flip back, and sure enough!
There is artemisinin, there is dihydro (hydroxy)artemisinin, which is Tu You's great invention, and there will be generations of research progress on artemisinin.
But what surprised Bai Ye was ......
There is no "Stable Artemisinin Complex"?
All right...... It seems that this article is not enough to go down in history......
Bai Ye smiled awkwardly, continued to flip back, and sure enough, I saw it!
Variant Polycarboxyl Artemisinin: The Second Revolution of Artemisinin, Time: 2018-12-12, Magazine: Cell, Issue Number: 20181201, Authors: Karrisi-Pall, Dasily-Belak...... Instructor: Tu You.
After Bai Ye opened it, seeing the journal number and name on it, Bai Ye was suddenly stunned, this is not ...... And Karis, and Desley...... These are acquaintances!
However, they all discovered this variant polycarboxyl artemisinin at the end of 2018, and Bai Ye looked at it carefully, and it clearly described the discovery of this artemisinin.
In 2018, the medical team sent by the state to aid the continent had a traditional Chinese medicine doctor, who happened to use Baihu soup to cure the local epidemic malaria in the process of aiding Africa.
Finally, a substance called stable artemisinin complex was successfully isolated and purified in traditional Chinese medicine.
This complex can react with nucleic acids in the malaria parasite under special circumstances.
This nucleic acid and stable artemisinin complex forms variant polycarboxyl artemisinin within the cells of the human body.
This variant polycarboxyl artemisinin is a key ingredient in the treatment of artemisinin-resistant Plasmodium.
Bai Ye was a little dumbfounded, this series of news made him feel that his brain cells were not enough!
It turns out that the key is the stable artemisinin complex that I discovered?
As long as the artemisinin complex reacts with the nucleic acid in the malaria parasite under specific circumstances, the so-called variant polycarboxyl artemisinin can be obtained.
Is it really possible?
If you can, you can complete your advanced, intermediate, and advanced tasks!
The more Bai Ye thought about it, the more excited he became. Myself...... Ahem...... Do you want to be the man who saves the world?
Thinking of this, Bai Ye suddenly felt a little weak......
I am so dazzling...... Won't people be jealous?
Ay!
Moreover, it's obvious that I'm cheating, okay?
The opening was so obvious that it made Bai Ye blush a little.
Bai Ye secretly thought: Actually, as long as I study more, I can also study this thing.
As long as you give me time, you can just leave it unplugged.
And...... And the discovery of stable artemisinin complex is a real strength!
After comforting himself, Bai Ye immediately started his operation, the nucleic acid of the malaria parasite?
Bai Ye originally wanted to go directly to Daisley, because although she was in charge of modeling, she was mainly studying the physiological functions of the malaria parasite, but Bai Ye thought about it and dispelled this idea, how to explain it?
There's no way to explain it!
By the way, what's written in the book?
The Chinese medicine doctor was called Tan Bao, and he was giving it to the patient at the time...... It is "White Tiger and Guizhi Soup"!
Bai Ye found the mice for the experiment, extracted the tissue with the malaria parasite, and then began to isolate it under the microscope......
Plasmodium is a single-celled organism that reproduces by nuclear fission to become schizonts.
Bai Ye obtained nucleic acids in the nucleus during nuclear division.
Then Bai Ye reacted with the stable artemisinin complex extracted from the original experiment.
This reaction is more complex and requires a catalyst!
And their catalyst is a unique substance in the body's red blood cells.
How do you find red blood cells?
Let's just bleed!
After thinking clearly, Bai Ye directly used a vessel to drip his blood into it, and then divided it into several parts.
He put one of them into the malaria parasite as a sample for the malaria parasite, and then used the other as a reaction site, adding nucleic acid and a stable artemisinin complex.
…………
…………
Bai Ye observed under the microscope and was suddenly a little surprised!
It worked?
Really did it!
It seems that I am really the man who saves the world...... Even if I'm open!
Besides, people are hanging on their strength! Why report it!