P<0.05 and P=0.05 were originally a very undesirable thing.

It's easy to overlook because it's not worth looking into, and even a lot of research institutions think that P≤0.05 is okay!

But Bai Ye happened to encounter such an extreme probability event.

Of course, even P<0.05 does not mean that it is valid, only that it is 95% probable!

So, regressing to statistics, it's all a matter of probability, and even if something goes wrong, it may be a first-class error or a second-class error or even a low-probability error event.

Bai Ye took a deep breath and continued to start a new round of calculations.

Is it a Class 1 error and a Class 2 error?

Bai Ye was about to start calculating, when he suddenly found an aunt standing beside him and said, "Young man, why don't you go back so late?" ”

Bai Ye just looked at the time, it was half past ten, and when he looked at his aunt, he hurriedly said sorry.

What a familiar scene...... When I was admitted to graduate school, the library was closed, and it was this aunt, right?

Bai Ye returned to the dormitory and didn't do anything else, but took a closer look at the lost data.

This data is not much different from others, maybe at the time I thought that losing it would not have much impact?

Bai Ye didn't know how to think about this kind of thing, so he consulted Karis and Daisley for this P=0.05 consideration.

They think that this probability is very small, and it may be possible to reduce it by using a different method of calculation, or to come up with some unnecessary data.

But Bai Ye felt that this kind of real data could often reflect the problem, and what was obtained after elimination was not perfect!

What to do?

Why did Bai Ye bother with this problem, because first of all, this problem may be the reason for the failure of the experiment.

First of all, it may be because of the results of this animal experiment: in fact, this drug cannot change or reduce the incidence of tumors.

Another possibility is that although the drug can be effective in mice, it is not effective in humans.

The main purpose now is to prove both of these points.

Bai Ye thought about it all night, and got up at dawn the next day and went to the library, the same location.

He suddenly remembered that when he learned lv6 in statistics, there were many new test methods.

Bai Ye hadn't tried these methods, so he rearranged the data and started the calculation according to the new model.

It didn't take long for Bai Ye to calculate the results!

But the result made Bai Ye stunned!

It's effective!

This drug is effective for gastrointestinal tumors in KM mice......

So why is there such a series of effects?

Or even sped up?

Could it be that the experiments on digestive tract tumors in KM mice are not very effective?

Hasn't anyone studied the compatibility between mice and humans?

Generally speaking, KM mice are commonly used to study tumors, is it unreasonable? Especially in those directions of digestive tract tumors, is there a problem?

Bai Ye suddenly remembered his book of Thackle's "Tips for Raising Rats", and Bai Ye hurriedly opened the virtual screen to check it out.

Do you have...... Do you have......

Bai Ye was a little moved, if it could be confirmed...... This is a new discovery!

KM mice are not suitable for the study of digestive tract tumors, and once this theory is confirmed, it will definitely be a big discovery!

Found it! Found it!

Thacker wrote a sentence in his experience: KM mice will change their DNA transcription sequences in some drug-specific experiments, which is a special targeted drug, which is simply suitable for KM mice, not humans, and the human trial ended in failure......

Bai Ye suddenly realized!

Is that so?

What is the drug and what is the cause?

Bai Ye hurriedly continued to look through it, and found that the DNA sequence of KM mice is relatively adaptable, and when faced with some strong stimuli, it can mutate faster than humans?

Then he gave many examples to prove some shortcomings of KM mice, and the end of the article also said that the original experiment caused some data gaps due to the loss of original data.

In fact, this is an opportunity for further improvement of KM experimental mice, and if the cause of that variation can be eliminated, it may be perfectly applicable to modern tumor research.

Bai Ye was stunned for a moment, and quickly flipped over to look at the name of this experiment: Dr. Mikasu-Tranri's research on the use of a synthetic compound to target and curb single-cell cancer.

Dr. Mikasu Tranry?

Bai Ye got up and walked to the toilet, and he didn't care about the time, so he directly dialed Keao's phone.

But he eased his breath: "Hey, Koo, have you been busy lately?"

Ke Ao's voice was lazy: "Oh!Bai Ye, what time is it......

Bai Ye said apologetically: "I'll figure out some results for your data." By the way, what's your mentor's name?"

As soon as Ke Ao heard Bai Ye's words, he immediately woke up: "What?

Bai Ye was stunned for a moment, shook his head, and continued to ask: "For the time being, a little bit, when I have the results, I will tell you, who is your mentor?"

Koo sighed, "I'm ...... But the old man is gone...... Depression, suicide. ”

Bai Ye was stunned, sure enough, it was him, but ...... Why committed suicide: "Sorry, thank you, wait for my good news." ”

…………

After chatting with Ke Ao for a few words, Bai Ye hung up the phone, he couldn't tell Ke Ao to complete the data himself, but he could study it along the lines of whether the data was correct.

Since the data is correct, then there is a problem with mice, so what is the problem?

Bai Ye returned to the study of the second part of the data, and it was still the key missing data......

For the next day, Bai Ye used all the calculations.

Following the data to dig, Bai Ye is very experienced, and it is not the first time that he has done something along the vine.

On the third night, Bai Ye looked at the data excitedly, and there was a result!

Mainly combined with the first stage data, it turns out that in a molecular sequence, a guanine can easily change the structure of its DNA during RNA transcription!

If the guanine of the KM mouse can be eliminated and the original DNA sequence can be changed, the rate of mutation can be slowed down.

In this way, it is not good for the mutation of mice, but it is good for experiments!

Bai Ye was a little excited.

I am destined to make history......

The new type of mouse is suitable for the study of tumors, and Bai Ye feels excited when he thinks about it.

Now it's time to experiment, and if the results of the experiment ...... I, Bai Ye, am destined to become the man of the Rat King......

Although the name is not good, it ......

Any job, to achieve the ultimate, is art!

Moreover, now Bai Ye is still carrying the task of this Keao, and it is a task with rich rewards!