Helan's jumping incident not only did not increase the negative impact on Puze, but brought it a good reputation bonus.

As for the development of the follow-up matter, Bai Ye didn't pay much attention to it, because Chang Lili took leave, took annual leave in advance, plus sick leave, and may have to rest for a while.

It may be that Helan's matter has had some big or small impact on her, Helan went to submit an application, and the leader quickly approved it.

The director of the fifteenth floor department is called Zhao Xiaojun, who was originally the deputy director under Jiao Liming, and later after the establishment of the mental health department, Zhao Xiaojun became the director, so Zhao Xiaojun has always respected Jiao Liming.

After Chang Lili rested, Zhao Xiaojun found Bai Ye and asked him if he had any intention of staying in Corey for a while, Bai Ye did not refuse, and decisively agreed.

Because during this period of time, when I was on the fifteenth floor, I had a lot of feelings for Bai Ye, and even had a lot of feelings for Bai Ye's future medical career.

If you are sick in your body, you can adjust it by adjusting your body, but if you are sick in your heart, how can you treat it?

Bai Ye began to ponder over this question.

The most common of the fifteenth level of diseases are depression and anxiety, in fact, these two are completely different diseases, both manifestation and treatment, starting from two diametrically opposed directions.

Depression is a common mental illness characterized by long-term depressed mood, and the symptoms are often inconsistent with the environment.

Moreover, this disease is terrible, once depression occurs, it is easy to recur, but each attack can be relieved in most cases, and in some cases it will leave sequelae or turn into a chronic course.

Depression can be caused by a variety of causes, but it is often accompanied by loss of interest, low mood, self-blame, guilt, lack of self-confidence, loss of energy, poor sleep, and decreased appetite.

At least 10% of people with depression will have manic episodes, known as bipolar disorder, some with significant anxiety and motor agitation, and in severe cases, psychotic symptoms such as hallucinations.

According to statistics, 2/3 of patients with depression have suicidal thoughts, and the suicide rate of patients with major depression is as high as 10%~15%, while 30%~70% of suicide deaths are related to depression.

So, with such a high mortality rate, can any other disease compare with it?

Anxiety disorder is also a common mental illness with unpleasant and painful and often accompanied by physical discomfort as the main symptoms, 3.66%~28.8% of people suffer from this disease for life, more than 90% of patients are onset before the age of 35, and there are often more female anxiety disorders than men.

Although depression and anxiety are two different mental illnesses, they often appear together clinically, and many clinical symptoms are the same, including poor sleep, decreased appetite, loss of energy, and irritability.

When depression and anxiety disorders are present at the same time, it is clinically diagnosed, which is one of the most common forms of comorbidity in psychiatric practice. Studies have shown that 60%~90% of patients with depression have anxiety symptoms at the same time, and more than 50% of patients with depression have anxiety disorders that meet the diagnostic criteria.

Why is anxiety called anxiety disorder, because most anxiety patients will have a feeling of physical disorder, this feeling, will make people feel uncomfortable, some people are palpitated, but there is no problem with the electrocardiogram, cardiac ultrasound shows that this is the heart function of normal people. Some people feel short of breath, wheezing, but the lungs are very good, and the respiratory tract is very normal, and so on......

The anxiety disorder method comes with a variety of discomforts, and this disorder is like a brain problem that controls discomfort in various parts of the body.

Moreover, there is no reason or solution for this discomfort!

Bai Ye didn't believe this, he felt that there must be something that controlled the spiritual emotions of the human body, and there would be some kind of dynamic balance substance in the human body, which would control the joys, sorrows, sorrows, sorrows, fears, and other emotions of the human being.

It's just that this kind of thing still hasn't been discovered!

If you are sick in the body, you can be treated, but if you are sick in the heart, how can you treat it?

It's like a terminal illness that afflicts all kinds of people.

When someone asks you, you may be generous, but if it's a mental illness, you may be embarrassed to say it.

Bai Ye now has a sense of mission, and he feels that he should work hard for it, to study the mechanism of these diseases, and then to solve this problem.

Because these diseases are too harmful!

He's not just hurting himself, he's constantly influencing others, even this society.

Studies have found that depression and anxiety affect others and societyDepression and anxiety disorders can have a significant impact on an individual's physical and mental health, work level, social skills and physical activities. Due to the low evaluation of their own physical health, and the decline of various social functions and physical activities of some patients, many social functions will be damaged, resulting in problems such as inability to work normally, marital discord, and parent-child relationship.

The impact of depression and anxiety on life and health One of the common symptoms of patients with depression and anxiety is that suicidal behavior occurs, which will cause great harm to themselves and their families, and even if suicide attempts, they will cause harm to their own body and will have the possibility of repeating suicide. Death due to depression and anxiety has become a major cause of death in the population.

And!

This disease is hereditary!

That's right, he will be hereditary, studies have found that the occurrence of depression and anxiety disorder is closely related to heredity, and the probability of the same disease between relatives is much higher than that of the general population, 8 ~ 20 times that of the general population, and the closer the blood relationship, the higher the consistency of the disease, such as parents, brothers, and children's immediate relatives can reach 12% ~ 24%, dizygotic twins are 12% ~ 38%, monozygotic twins reach 69% ~ 95%, and cousins have 2.5%.

Other data show that the role of genetic factors increases with age. Current studies have not fully revealed the specific inheritance mode of depression, and the expression of abnormal genes or the failure to express normal genes is the mechanism that causes most psychiatric disorders. The combination of genetic mode and environmental and psychological factors often affects the occurrence of depression, and it is determined that depression and anxiety disorders are mostly polygenic genetic diseases.

Bai Ye felt that since this was a genetic disease, there must be a substance, which was constantly changing the genes of human beings, so that a kind of genetic structure would be formed and the result of heredity.

Therefore, after wanting to understand this, Bai Ye began to prepare.

Every day, Bai Ye got up early and greedy for darkness, and he consulted all kinds of literature to study what caused this change.

During this time, Zhao Xiaojun also began to admit patients one after another, and I have to say that after truly understanding the patients, he went to read books after passing the clinic, and he got more things and made faster progress.

Bai Ye pushed everything around him during this time, and spent the whole day researching the causes and treatment options of anxiety disorders and depression.

Time is always merciless and fleeting in the blink of an eye, but after Bai Ye has undergone clinical tests, he has found several things related to anxiety and depression that are currently monitored.

From a biochemical point of view, the main factors include 5-hydroxytryptamine (5-HT), norepinephrine (NE), dopamine, acetylcholine, and aminobutyric acid.

These five indicators are directly related to human anxiety and depression, and now at present, a variety of drugs are also treated according to these five biochemical components.

However, these tests are extremely expensive, and this is not a simple laboratory test and blood draw, and it is extremely expensive to detect these human substances.

However, if you really want to treat thoroughly and have a good effect, you have to study the true level of these five indicators in each person's body.

If you want to study this thing thoroughly, the next thing to do is to start with these five indicators, investigate each inpatient, and then score the patient's symptoms, conduct meta-statistical analysis, and analyze the research results.

Only by thoroughly studying these things, the treatment, that is, the treatment of the syndrome, is good.

After thinking it through, Bai Ye felt that he should treat this matter as his graduate project.

However, before that, Bai Ye checked all the cases since the construction of the department on the fourteenth floor through the computer in the past ten years, and these cases were all cases of treating patients after the establishment of the psychiatric department

Every hospitalized patient has an inpatient record, which is valuable research information.

It has been less than a decade since the popularization of computer cases in Puze Hospital, but the psychiatric department on the fifteenth floor has been established for a long time, and many patients' cases are handwritten, and in order to figure it out, it is necessary to study historical cases.

So Bai Ye found the case room, where the cases of the hospital for twenty years were sealed.

Each patient has a medical record, and after discharge, the paper version of the medical record is sent to the medical record room, and the hospital keeps it for 20 years, during which the patient can use his identity information to copy and investigate the case.

At the same time, doctors can also investigate cases to do research.

However, the latter is relatively rare, and many cases of patients after discharge, doctors will put them on the shelf and will not study them at all.

Because many doctors have been reduced to hard work and have lost the instinct to think.

But Bai Ye is not like this, he knows the importance of these things, these are countless research experiments and data, very detailed, each case is a very comprehensive research data.

Bai Ye spent half a month, running to the case room every day when he was free, and he went to count all the data he needed.

Finally, he sorted out the data and carried out various statistical analyses.

During this time, Bai Ye can be said to have devoted himself to it.

In the end, Bai Ye had a result for the treatment of anxiety and depression on the fifteenth floor of Puze Hospital.

Medication is the mainstay of treatment for depression.

He found that no matter how rapid the development of antidepressants is, how many varieties and types increase, according to their chemical structure, they can only be divided into two heterocyclic antidepressants: tricyclic and tetracyclical.

Tricyclic drugs are classic antidepressants that are currently mainly classified by mechanism of action, mainly including selective 5-HT and NE reuptake inhibitors (e.g., venlafaxine); selective 5-HT reuptake inhibitors (e.g., fluoxetine); selective NE reuptake inhibitors (e.g., reboxetine); selective 5-HT reuptake activators (e.g., thoneprutin); NE and specific 5-HTergic antidepressants (e.g., mirtazapine); 5-HT balanced antidepressants (e.g., trazodone); NE and dopamine reuptake inhibitors (e.g., bupropion); Reversible monoamine oxidase inhibitors (e.g., moclobemide), etc.

In addition, traditional Chinese medicine is gradually accepted by the majority of patients due to its mild effect and few adverse reactions, such as hypericum perforatus, calamus, bupleurum, ginkgo, ginseng, centella asiatica, grapefruit, Inner Mongolia astragalus, acacia, etc., all have certain antidepressant effects. Therefore, the study of the antidepressant effect of traditional Chinese medicine and its prescriptions has great potential, and has great social significance for the treatment of the increasing number of depressed patients.

However, these drugs can only temporarily alleviate and suppress the development of the disease, but cannot cure it!

………………………………

………………………………

It's September now, and it's time to prepare for your graduation project.

Although he did not explicitly prepare the opening report, he also told everyone that it was time to start preparing for this matter.

When Bai Ye found his mentor, Liu Boli was sitting in the office reading a book.

At his age and point, there is no need to spend time in the hospital every day, but this strong old man comes to his place of work on time every day, whether it is in the outpatient clinic or in the office, he is very punctual.

Seeing Bai Ye come in, Liu Boli closed the book, Bai Ye rarely took the initiative to come to him, but every time he came, there must be something serious.

"Hello teacher. Bai Ye bowed.

Liu Boli nodded: "Sit, what's wrong?

He asked directly and straight to the point, in fact, he was very satisfied with himself as a student, and he always brought him unexpected joy from time to time, but wherever he went, it could be said that it had changed a lot!

The anorectal department has become a regional diagnosis and treatment center, a national key specialty, and a national anorectal demonstration site from a general department.

Just a few days after going to the 14th floor last month, the two directors of the acupuncture department and the encephalopathy department were alarmed, and the effect of facial paralysis recovery needles was very significant, and the facial paralysis recovery center was directly established.

And Wang Wenliang is also very clever, taking advantage of this opportunity, he directly applied for the project, and it is estimated that this time the National Natural Science Foundation will definitely not have to run.

If the research is thorough, this facial paralysis rehabilitation clinic has developed into a facial paralysis rehabilitation center, and all this is a matter of course, and it is not a problem at all

The Department of Encephalopathy is not as good as other departments, he was originally a key specialty, but now his development has reached a bottleneck, and every step is very difficult, but these bottlenecks seem to not exist at all in Bai Ye's place, and they can be broken with a small operation.

This kid is really a gift from God to Puze!

No, it should be a gift to Chinese medicine.

Liu Boli suddenly remembered that when Zhao Xiaojun met him, he said that Bai Ye had gone to the fifteenth floor and had been studying on the fifteenth floor for a while.

According to your own understanding of this kid......

Don't......

Thinking of this, Liu Boli suddenly became energetic, could it be that Bai Ye had any special views or ideas about the mental health department?

When the idea came to him, he could no longer contain his well-controlled heart rate......

Liu Boli took a deep breath, he felt that when chatting with Bai Ye, he should adjust his exhalation and heartbeat, so that he could not be surprised everywhere.

Bai Ye couldn't help but feel apprehensive when he saw Old Man Liu looking at him lightly.

"Teacher, that's right, I found in the psychiatric department that the treatment of depression and anxiety disorders is somewhat inappropriate at this stage. ”

"Through a large number of research materials, I found that from a biochemical point of view, the possible factors affecting the development of the disease mainly include 5-hydroxytryptamine (5-HT), norepinephrine (NE), dopamine, acetylcholine and aminobutyric acid. ”

"Although many studies in recent years have supported the 5-HT hypothesis, studies have shown that 5-HT is directly or indirectly involved in regulating a person's mood, with decreased 5-HT levels associated with depression and increased 5-HT levels associated with mania; However, there are also many studies that report that the occurrence of depression is related to the content and regulation of NE, dopamine, acetylcholine, aminobutyric acid, etc., and more research work is needed to truly reveal the biochemical mechanism of depression and anxiety. ”

"Then I collected and counted the main methods and analysis of the treatment of the disease in our hospital over the years, and came to a conclusion......"

After Bai Ye finished saying what he had done recently, he said to Liu Boli:

"Teacher, I want to study this thing!"?