Ouyang Xuan's college entrance examination results after graduating from high school are very good, and he can fill in popular majors such as Fudan and Zhejiang University Computer Science, but he likes medicine, which is related to his mother.

He was determined to develop drugs that could treat all kinds of incurable diseases, such as depression and schizophrenia in his mother, and cancer.

Despite his father's opposition, he chose pharmacy as his first choice in a key medical university in China.

After entering the university, he listened carefully to lectures, reviewed carefully after class, and went to the library to consult materials, hoping to delve into the mechanism of drugs.

In my freshman year, I decided to continue my studies after graduation, master's students, doctoral students, and go abroad for further study......

In short, Ouyang Xuan aspires to become a famous scientist in the research of original drugs (RLD)!

With the deepening of his reading and in-depth understanding of the cutting-edge research of domestic drugs, he found that the basic development of domestic original drugs is quite lacking.

Under the tide of reform and opening up, all universities and scientific research units are looking at money and have established drug research institutes and drug development companies.

The establishment of these units is not to engage in the research of original drugs, but the research of generic drugs, not to study the mechanism of drugs, but to develop drug dosage forms to meet the current national new drug regulations and new policies.

The so-called "national new drug", "exclusive variety", and "exclusive dosage form" are the same kind of drug, and the dosage form is changed, for example: from granules to tablets, from tablets to capsules, soft capsules, concentrated types, etc.

Every time you change it, you can get the title of "exclusive variety", the title of "national new drug", and then the seven-year exclusive variety protection period, Yunyun.

Pharmaceutical companies have the title of so-called "exclusive variety", or the title of "national new drug", and can apply for high quality and high price, so as to monopolize the market and sell well.

The teachers of the Department of Pharmacy are either hired as consultants by a pharmaceutical company, or they cooperate in the development of new drug dosage forms, and use national resources in disguise to enrich their own pockets.

This disappointed Ouyang Xuan, who was depressed for a long time and learned to smoke and play cards and fall in love......

In his junior year, he met Mr. Qin Hanyun, a young professor who had just returned to China after graduating from a famous university in country M. After several exchanges, they became teachers, students and close friends, and they often discussed career and life together.

"Teacher Qin, why is there such a big gap between the development of original drugs in China and Western countries?" Ouyang Xuan couldn't help but ask.

Professor Qin smiled and replied:

"There's a lot going on in that, I'll talk about it. For more than 100 years, China's scientific and technological development has lagged far behind that of the developed countries in the West, except for the wars and the institutional turmoil of the sixties and seventies. Since the reform and opening up, people's utilitarian thinking is making trouble, many people are short-sighted, engaged in imitation drugs to make money, specifically staring at the varieties of foreign patent protection that are about to expire, picking up imitations, some foreign countries have eliminated the replacement of products, but in the country it has become a sweet spot. ”

"In terms of the definition of drugs, the FDA only has 2 types of drugs, namely innovator drugs (RLD) and generic drugs (ANDA). Original R&D drugs, i.e., original new drugs, are approved for marketing after thousands of chemical compounds are screened layer by layer and rigorous clinical trials. It takes about 15 years of research and development time and trillions of dollars, and only large multinational pharmaceutical companies are capable of developing it. To put it bluntly, the research and development process of new drugs is the process of survival of the fittest, and at present, China can only rely on the national strategy to start. ”

"China is a country that mainly produces generic drugs, and with the deepening of reform and opening up, original research and development drugs have been taken seriously. Developed countries are both. The concept of the difference between the efficacy of original drugs and generic drugs has been deeply rooted in the minds of doctors and patients in developed countries. In foreign countries, when a patient goes to a pharmacy with a doctor's prescription to dispense medicine, the pharmacist will ask the patient, do you want the original drug or the generic drug? Such a situation is unimaginable in our country!"

"The scale of domestic pharmaceutical companies is not large, and the sum of a dozen or even dozens of companies is not as large as a foreign company, so this is a problem. Because these domestic enterprises also need to survive, he can only do short, flat and fast things. ”

Qin Hanyun still told the reason to his students in general.

"Teacher Qin, do you still insist on the research of the original medicine?" Ouyang Xuan felt that the teacher's ideals had also changed.

"Of course, I will never swerve this concept to the death! But I will also adapt to the domestic environment according to local conditions, solve the problem of survival first, and then apply for the National Scientific Research Fund to do basic research, and then follow in clinical trials or later stages, and cooperate with powerful enterprises and visionary entrepreneurs. This kind of thing can't be rushed, you have to take it slowly, and you treat it as a lifelong career to complete. ”

Mr. Qin's realistic description made Ouyang Xuan suddenly realize that there is a long way to go in the research of primary drugs, and it must be completed as a lifelong career. The priority should be to make money first, and when you have enough money, you can do what you want to do.

When he was about to graduate from the four-year university, his father originally wanted him to take the postgraduate examination, and his graduation advisor, Professor Qin Hanyun, also hoped that he could take the postgraduate examination for his own master's degree, and at least keep his dream by staying in the school or scientific research unit. But he didn't adopt it, not because he didn't want to read it now, the ideal in his heart has not changed, and he just wants how to save money quickly and gather wealth at the moment.

On the eve of graduation, Ouyang Xuan was thinking about where to make money after graduation, and when he was wandering, he met the brothers and sisters who went to sell drugs in a pharmaceutical factory after graduating a few years earlier, and now returned to his alma mater to help his company recruit troops.

After a few glasses of wine, the first senior brother patted Ouyang Xuan on the shoulder and said in the tone of a senior:

"Brother, with your height of 182, your athlete-like strong physique, handsome appearance, eloquence that can speak, and the right profession, you don't 'fuck' do medicine, who is appropriate? Hah!"

The brothers and sisters continued:

"Now there is a saying circulating outside, 'In addition to robbing banks, selling drugs is the most profitable!'

"Ouyang Xuan, just with your conditions, you are born to be a medical representative, you are going, those beautiful women's deans, directors, doctors, nurses and sisters will be settled, and there are big bills, ha... Hah..."

“……”

Listening to the sensationalism of the senior brothers and sisters, Ouyang Xuan felt that it made more sense, and suddenly his blood boiled, and he slapped his thigh:

"Brother, I have long wanted to sell drugs to make money, and now my position is firmer, let's join the army of selling drugs with you!"

This pharmacy major does not have much prospect as a graduate student, but instead works as a "medical representative" to sell drugs to make money quickly and accumulate money quickly.

After repeated comparative thinking, Ouyang Xuan chose a pharmaceutical company recommended by his senior brother Zhang Shangrong, "X Pharmaceutical Company" located in the southwest

This company has been established for more than 4 years, has several Class III 'national new drugs', and is developing Class II new drugs, the market belongs to the growth and development period, and the policy is flexible.

The founder of the company is also a graduate student who studied medicine, went to the sea to do sales in a pharmaceutical factory in Hainan, and only started his own pharmaceutical factory after making money, such a development trajectory is what Ouyang Xuan imagined, and he admired it as a role model.

After getting his graduation certificate, he went straight to Southwest G City for a field trip and finally decided to start his own future at "X Pharmaceutical".

After a physical examination of filling out the form, it is a few days of basic product knowledge training and drug regulation training, as well as a little marketing knowledge training.

Then he was assigned to the marketing department in Kyoto, a region in North China far from his hometown, and belonged to the district workstation of his senior brother Zhang Changrong.

……

One day in early August 1998

Hangcheng South Railway Station

The train "bluffed" and jolted hard, and the K-time express train to the capital started slowly, and the pillars of the platform passed in front of you one by one and slowly moved backwards......

Ouyang Xuan, who had just entered the carriage and found the sleeper berth, threw the luggage on his shoulders onto the luggage rack, rushed to the window, lifted the window with both hands, and stretched his head out of the window and twisted forward to see off his aunt and second cousin:

"Auntie, go back, please take care!"

The eldest aunt stretched her neck with tears in her eyes, dragged her sick body and followed the slowly accelerating train trot with the support of her second cousin.

"Be careful along the way, Xuan!"

The eldest aunt shouted loudly, and only then wiped the tears from her face and walked back when she saw that the train had gradually become invisible.

Ouyang Xuan couldn't see the figure of the eldest aunt and them from the car window, almost gritted his teeth and closed the window, and returned to his seat upside down, unable to help but feel a little sad.

Ouyang Xuan, who lost his mother's love since he was a child, regarded his aunt as his biological mother.

Because the Xue family was born in a big capitalist, the eldest aunt was also sent to the countryside of Hangzhou suburbs when she was young, and later married the local rural youth and had three daughters.

She has always regarded her poor deceased sister's widow as her own son.