Through the comparison of data, Henry found that his genes were very different from those of ordinary people. Although there are great differences between each person's genes, Henry's pair of XY sex chromosomes, especially the Y chromosome, is much larger than the average person's Y chromosome. In other words, Henry's Y chromosome has a much larger number of genes than the average person!!

This is just so abnormal!

"Mr. Williams, when we first met, we were also very shocked and confused!"

The speaker was Professor Thomson, who was sixty or seventy years old and was in charge of gene sequencing, "After careful study, we found that you have 10 more types of genes on your Y chromosome than the average person. Of course, there may be genes that we haven't discovered. You know, the Y chromosome is the most structurally complex of all chromosomes, and it has too many duplication genes to be easily detected!"

Henry nodded when he heard this, because the Y chromosome is indeed the most difficult to detect, and it was only successfully detected in 2010 in his previous life. Because there are too many duplicate genes or useless genes in the Y chromosome, and it constitutes a very complex palindromic structure. It takes a long time just to study and figure out this palindromic structure.

Palindromic structure refers to double-stranded DNA containing sequences that are identical in structure but in opposite directions. For example, one is "ABCDE" and the other is "EDCBA". Although it may seem simple, it is not easy to find a pattern in the complex Y chromosome. The Y chromosome is complex like a mirror, and researchers stand in the middle of countless mirrors to find the answer – the type and number of genes. This is an astonishing amount of work, and it took a huge amount of manpower and material resources to complete the rough examination of the Y chromosome.

"Mr. Williams, the mutation in your brain is probably related to a new gene on the Y chromosome! Professor Thomson paused abruptly, as if thinking.

After a while, he said, "Mr. Williams, do you remember when you fainted because of a brain mutation?"

Henry nodded and said, "Yes." ”

"Hmm...... At that time, Dr. Rothman gave you a test, and it was found that your cerebral cortex secretes a mysterious T substance, which strongly promotes the active growth of brain cells. At that time, one conclusion was that the rapid growth of brain cells may lead to the shortening of the life of brain cells!"

"Yes!" Henry nodded, and couldn't help asking, "What's the matter, Professor Thomson, have you made a new discovery?"

"That's right!" Professor Thomson nodded, "After several years of follow-up testing, we have found that your brain cells do not show signs of aging, but are becoming more and more vigorous, with a lush and powerful vitality! Therefore, I speculate, there may be some other reasons why your brain cells have become so powerful! As for this reason, it must be related to your genes!"

When Henry heard this, his heart was overjoyed, and he had always felt that there was a stone pressing down on him, but now he finally let it go.

However, it didn't take long for Henry to be happy.

Professor Thomson poured a basin of cold water and said, "Mr. Williams, because your XY chromosome is unusual to ordinary people, I am afraid that you will have great difficulty in fertility!"

"What do you mean by that?!" Henry couldn't help frowning.

"According to our research, the Y chromosome and the X chromosome are not a match made in heaven, but more like a pair of rivals who do not give in to each other!"

"The X chromosome has 1,438 genes, while the Y chromosome has only 45 genes. 300 million years ago, the primitive ancestors of sex chromosomes X and Y were no different from ordinary chromosomes, and they all carried out normal DNA replication, chromosome union, and recombination and exchange of homologous genes in the process of inheritance. But one day, the Y chromosome suddenly mutated, and a gene called SOX3 on one of the original sex chromosomes mutated and became a gene called SRY. According to our research, the SRY gene should be the key gene for the male sex! ”

"In order to further strengthen their respective sexes, the X and Y chromosomes evolved more genes that favor gender prominence, and eventually formed a genetic base camp for maintaining sex characteristics. The genetic members in such a base camp are not at all friendly to the members of the other side. Genes on the Y chromosome that are good for males are often bad for females, and conversely, genes on the X chromosome that favor females always try to destroy the male trait. So, when the two are combined, they attack each other. However, in the process of long-term confrontation and evolution, the Y chromosome and the X chromosome have reached a tacit cooperation so that they can continue to reproduce. Now Mr. Williams, your problem is that your Y chromosome has 10 genes more than the Y chromosome of ordinary people, and this difference is difficult to ensure that the woman's X chromosome and your Y chromosome are combined! At the same time, your X chromosome has also undergone a lot of changes, and the problem is not small......

Henry frowned, the situation was indeed as Professor Thomson had said, and he was in great trouble with fertility.

"Mr. Williams, don't worry too much. I'm sure we'll come up with a solution someday!" Professor Thomson reassured, "and besides, there's a chance that your XY sex chromosome will be combined with Mrs. Williams' X chromosome, and it's just a little smaller than the average person......

"Thank you for your comfort, Professor Thomson. We won't talk about this question for the time being. I believe that as long as biotechnology is improved, there is no problem that cannot be solved. After Henry finished speaking, he paused and asked in a deep voice, "Professor Thomson, how is the research on the new generation of gene sequencing technology?"

"It's going very fast, and in another month or two, it'll be done!" replied Professor Thomson.

"Hmm!" Henry nodded in satisfaction.

The traditional method of genetic testing is the use of optical sequencing technology. Four different genes are labeled with different colors of fluorescence, and then the fluorescence signal is captured with a laser light source to obtain the sequence information of the gene to be tested. This method of detection is reliable, but it is expensive. The price of a sequencing instrument is 500,000 to 750,000 US dollars, and the cost of a single test is as high as 5,000 to 10,000 US dollars. It is also thanks to the fact that the gene umbrella company is very rich, and it can still produce and reduce costs, so a large number of instruments are manufactured for gene sequencing work. And all the institutions or companies that conduct gene sequencing research in the world do not use as many instruments as gene umbrella companies.

The latest genetic testing method is to use a chip instead of a traditional laser lens, fluorescent stain, etc., and the chip is a sequencer. With a semiconductor sensor, the instrument directly detects the ion currents generated during DNA replication. When the reagent enters the chip through the integrated fluid pathway, the reaction pores densely packed on the chip immediately become millions of microreaction systems.

This combination of technologies enables researchers to obtain genetic information in as little as 2 hours. With traditional optical sequencing techniques, it takes weeks or even months to get results. At the same time, the cost of a single test has been reduced to a minimum of $1,000.

Henry thought for a moment and said, "Now that a new generation of gene sequencing technology is about to be developed, it's time to update it!" Professor Thomson, let us get rid of the equipment we have on hand as soon as possible!"

"Okay!" Professor Thomson nodded.

"Next, first sequence all the mutant genes of the gene umbrella X experiment, I want to get their powerful mutant genes!!" Henry's eyes flashed with a gleam......

"Understood, I'll do it right away!!"

(To be continued.) )