Chapter 124: Generic Drugs and Clinical Trials
Amgen's granulocyte biotherapeutics have been submitted for the last large-scale clinical trial in more than 3,000 people.
It's just that it's still in the hiring stage, hiring those professional drug testing personnel in the territory of Midi. It is said that it is a profession, but in fact, it is some poor bastards, some low-level whites and most of the slum Nigo, these people choose to use their bodies as a new drug business to get a lot of money.
There are many pharmaceutical companies in the United States, and it can be said that most of them are giants. This has led to a very tight supply of drug testing personnel, and the cost of drug testing has gradually increased, rising every year.
Now, after several clinical trials, as long as the drug is successful, a drug tester can almost earn tens of thousands of dollars. The test personnel of a new drug need about 3000~5000 people, and even higher needs tens of thousands of people.
One or two are not obvious, so many people look at it, the cost is very staggering. For example, Amgen Pharmaceuticals lost more than $10 million in the last large-scale clinical trial that failed. Even if it is successful this time, it will almost need this number.
As soon as I entered the company.
George Lasman explained this problem like Abel, although the company can now pay this amount because of Abel's capital injection, but such a large amount of one-time expenditure, George Lasman, as the chairman, still needs to report to the boss Yabo Abel.
Although the chairman of most companies is actually their boss, but at present, due to some special relationships, Abel has not yet thought of seizing the chairmanship of George Lasman, and the chief scientist is also doing a good job, so Abel will continue to serve as the chairman of the company.
"Is it more than 10 million US dollars?" Hearing that the cost of the last clinical stage alone requires such an astonishing cost, Abel couldn't help but be a little stunned, sure enough, the development of new drugs in Midi is not something that ordinary companies and ordinary people can afford.
The last time he developed the little blue pill [sildenafil] was a trick, and he only did the first successful clinical trial and ended it, and then sold it to Pfizer, saving the cost of the next three clinical trials.
In the first clinical trial, the FCA only required a minimum of 50 people. However, the second time it will require at least 200 people, the last time it will be at least 3,000 people, and if it is a new drug for common diseases of the general public, it will sometimes require tens of thousands of people. The effort is staggering.
Like the first clinical trial of the little blue pill, Abel only hired 50 people. Everyone can get the fee, because it is the first experiment, it takes 2000 US dollars, plus the intermediary fee, the average head Abel has to pay about 2300~2500 US dollars.
Abel spent about $400,000 on the development of the blue pill, most of which was spent on renting laboratories and experimental equipment, but the cost of clinical trial drug testing also accounted for a large part.
George Lasman: "It's a necessary expense...... Even if we start now, the new drug will not be available until mid-May, about a month later. ”
"I understand. Of course, this is a necessary expense, but ......" Abel's voice suddenly paused, his expression became a little strange, and he looked at the senior executives of Amgen Pharmaceutical, who were not there, except for the president, and said softly: "I think." In fact, we can support the development of medicines in third world countries. ”
“????”
Everyone's expressions were a little puzzled.
They don't know how this boss has turned to this topic otherwise, and what does supporting pharmaceutical development in third world countries have to do with the last clinical trial of Amgen Pharmaceutical.
"For example...... India. ”
Abel said leisurely: "This country's generic drug technology is at the forefront of the world. I don't think it's good for them, but their government supports them, and we can't do anything about it. However, we can actually cooperate and license our pharmaceutical patents to them for a small fee and only allow them to sell in their own country......"
George Lasman was a little puzzled.
"Mr. Sephorosa. I know you're a good person, but we're a commercial company, not a charitable foundation. We don't have to. ”
"yes. We don't have to do this, those Ah San don't pay patent fees, just make generic drugs. Why do we still have to empower them, and if we don't hold them accountable for what is already their government, how can we still help them?"
"That's right!"
“……”
A group of executives were against it.
This is also normal, if there is anyone to support it, do you have to suspect that this guy is the Virgin.
So is Abel the Virgin who raised this issue?
"Hehe......"
"Don't get excited. I still haven't said anything. Abel said with a smile, he looked at the crowd, "We can license the patent to them at a very low cost." But at the same time, we have one condition, that is, the company that has been authorized by us must cooperate with us and help us to conduct clinical trials of new drugs in their country. ”
As soon as this remark came out.
The surroundings fell silent.
Some of the top brass began to think.
The development of the pharmaceutical industry in this country can be roughly divided into four stages: before 1970, when foreign pharmaceutical companies were dominant; from 1970 to 1990, local pharmaceutical companies in India began to develop, in fact, they began to imitate; from 1990 to 2010, local generic drug companies developed in an all-round way, and at the same time began the export business of APIs and generic drugs, and the generic drugs they produced accounted for 90% of the world's generic drugs; after 2010, the local pharmaceutical companies began to pay attention to R&D and innovation, and challenged the innovative drug market.
It is now 1990, which is the beginning of the shameless Asan government and the Asan pharmaceutical company to fully plagiarize generic drugs, and it is also the time when they begin to be disliked by the world's pharmaceutical companies.
Therefore, the suggestion that Abel put forward earlier, these executives of Amgen Pharma will look disgusted.
But now that he raised the possibility, everyone looked at him differently......
Because......
Seems to be very operational.
They don't know.
The model proposed by Abel is the model and tacit understanding between the helpless Western pharmaceutical companies and them after the generic drugs of Asan Pharmaceutical Company reached the first place in the world.
Ah San provided untouchables to experiment with Western pharmaceutical companies, and Western pharmaceutical companies turned a blind eye to generic drugs......
In later generations, excessive pharmaceutical companies, such as HR, GLSSK, and even Asan pariahs, did live experiments, after all, clinical trials accounted for a large part of the R&D expenses.
The approach that Abel is proposing now is actually to make a very expensive clinical trial in the territory of Midi to Ah San, saving hundreds of millions of dollars in clinical trial costs that may be required for a new drug.
In Midi, if you hire a drug tester, if you are alone for all 5 times, as long as this person can survive, you can get about 10,000 US dollars, or even higher.
But in Ah San.
Abel felt.
Maybe $100 will do the trick.