Chapter 45: Second New Drug Patents
Wasted for a while.
After returning from Malibu Beach, Able decided to start his job in earnest.
A scientist!
Scientists include a wide variety of species, from natural sciences to humanities to social sciences, to computer sciences and mechanical sciences, and almost everything that can explain the planet can be called science.
But he is currently the most suitable for the project, and he is also the project with the fastest money. He thinks it's still chemistry and medicine in the field, the medicine project.
More than half a month ago.
He made sure that after the little blue pill, he was going to make something for the second time.
The reductase inhibitor he was going to make this time was just one of these inhibitors. There are dozens of reductase inhibitors that can be used as drugs in the data of the small wrecking ball in the next 30 years, but Abel is currently the most suitable to take out, and he thinks it is one of them.
This reductase inhibitor, it has its future chemical name: [R-(R'R')]-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(aniline)carbonyl]-1 hydro-pyrrole-1-heptanoate calcium trihydrate.
For non-specialists, it's like an astronomical symbol. But for people in the industry, in fact, if you give its chemical formula, a better medical chemistry team can even copy it without anyone's guidance.
Compared with the complex professional chemical name, it also has a relatively simple name for the drug, which is called atorvastatin calcium tablets!
The main therapeutic effect is patients with hypercholesterolemia and primary hypercholesterolemia.
To put it simply, the biggest effect of this drug is to lower blood cholesterol, lower blood lipids in the blood, and prevent high blood pressure.
A medicine that has absolutely no effect in times of war, but in times of peaceful development, works in the treatment of great wealth and disease!
During the war years, except for a very small number of high-ranking privileged people. Most of the common people, except for the familial hereditary. Most of the others are not eligible for high blood pressure.
However, in the era of better economic conditions, high blood pressure and high blood sugar, the two diseases of wealth, are too common among the population.
Especially among middle-aged people whose physical condition is gradually declining, almost seven or eight out of 10 people will have one of these two diseases, and at least three people will have both of them.
In this case.
The effective treatment of these two diseases of wealth, of course, its sales are not doubtful.
Abel will choose to copy atorvastatin calcium tablets because he found that there is no effective and low-side effect drug for the treatment of high blood pressure, high blood lipids and high cholesterol on the market.
Most of the drugs available to treat these symptoms are either slow to act, and a larger part are too side effects.
Before the future Pfizer Atorvastatin calcium tablets are officially launched, most of the drugs on the market are not very conspicuous.
As a result, hypertension is a frequent occurrence of diseases in Europe and the United States, but there is no good way to treat them. Everyone had to endure the consequences of slow effect or large side effects, and slowly take medicine to cooperate.
If you want to know the future of this drug, you can actually look at two data more than 20 years later.
In 2016, the sales of atorvastatin in urban public hospitals in China was 6.075 billion yuan, the market size of atorvastatin in retail pharmacies reached 2.431 billion yuan, and the total market size of the two mainstream terminals was 8.506 billion yuan.
Then in 2017, the sales of atorvastatin in public hospitals in key cities in China were 6.559 billion yuan, and the sales of atorvastatin in retail pharmacies reached 2.895 billion yuan, and the total scale of the two mainstream terminal markets reached nearly 10 billion yuan.
Basically, the better a country's cardiovascular disease treatment drugs sell, the better the people of that country are eating. Because only people who eat well will be prone to cardiovascular disease because of excessive nutrition.
And not wait until more than 20 years later, in 1990, even with many side effects. But those drugs that treat cardiovascular disease, in the United States alone, have annual sales of more than $2 billion. Not to mention spreading to the entire European and American society, the annual sales are estimated to easily reach 40 to 5 billion US dollars.
The reason is simple.
The daily diet of Europe and the United States is too high in protein intake, and most countries have become developed countries very early.
Like said above.
If you eat well, you are more likely to get cardiovascular diseases, which also leads to a considerable market for the treatment of cardiovascular diseases.
Especially the United States.
One of the biggest effects of sucking blood from the three mountains in the world is that even poor people in this country can easily get a lot of meat intake, so that they have more fat people......
Before the advent of atorvastatin, this type of disease treatment drug cannot be said to be a blank slate, but there is no mainstream drug in the middle, but it is real.
In the "original script", Pfizer was not officially developed and marketed until 1998. Then for the next few decades, the type of drug continued to dominate atorvastatin's annual sales.
Its profit and stable sales potential are completely out of the blue pill that Abel copied before.
After all, there are some normal people who still don't need to take the little blue pill, or don't take the little blue pill at most, which means that the duration is shorter.
But guys with high blood pressure, high cholesterol, and high blood lipids. If you don't take this medicine to treat the drug, it will be painful and abnormal when you get sick, and even death is not guaranteed.
One is to enjoy.
One is lifesaving.
Atorvastatin, of course, has a larger market.
After deciding on the route of his own research and development, he contacted several large pharmaceutical companies in the federation and several other large pharmaceutical companies in the world in Alvertli some time ago.
That's why.
There are two main reasons.
The first reason is that the auction type of the blue pill sells the patent, which gives him a taste of the sweetness. In the case of competition, pharmaceutical patents can be sold at a better price.
And the second reason is that this time he is not going to do experiments in the laboratory at the University of California.
It's not that he dislikes the University of California's labs that aren't advanced enough or that they're too expensive.
As one of the best public universities in the United States, the University of California is not as famous as those private schools in the Ivy League. However, in fact, the research and development capabilities and teaching capabilities in the academic world are actually among the top in the world.
The various laboratory conditions at the University of California, in this case, are also excellent. It's just that Abel is not ready to do the experiment by himself this time, in that case, even if something can be copied directly, it will take more than a month to get it completely done.
This time, he is going to find some assistants and act as a mentor himself, so that others can directly follow his guidance and copy it.
In some game terms, this time he is going to be the head of the regiment, commanding his MT, DPS and nurses to attack the big boss of atovastatin!