Chapter 304: Who the Hell Is It?

AIDS, cancer, leukemia, motor neuron disease (ALS) and rheumatoid are among the world's top five incurable diseases by the World Health Organization, but even today, only leukemia can be cured by bone marrow transplantation.

Cancer, second only to AIDS, is the second most terrible terminal disease in the world, with about 8 million people dying from this disease every year in the world, and China accounts for a quarter of it, with more than 2 million people every year!

Such a huge number of deaths, coupled with the incurable characteristic, and the physical and mental destruction of the patients themselves and their families, have almost reached the point of talking about cancer.

The term "cancer" in the general population is customarily used to refer to all malignant tumors.

In medicine, cancer actually refers to malignant tumors that originate from epithelial tissue, which is the most common type of malignant tumors.

Correspondingly, malignant tumors originating from mesenchymal tissues are collectively referred to as sarcomas, such as soft tissue sarcoma, etc., and there are also a few malignant tumors that are not named according to the above principles, such as Wilms tumor and malignant teratoma.

In fact, in addition to the possibility of early cancer cured by surgery, radiotherapy and chemotherapy and other internal and external means, the mortality rate of advanced cancer has reached almost 100%, which can only barely prolong the survival period of patients.

In other words, once it is confirmed that the cancer is already in the advanced stage, how long the person can survive is actually a matter of providence.

The reason why Liu Feng wanted to develop this new drug for cancer was largely affected by his uncle's illness.

Although birth, old age, sickness and death are human nature, however, an iron-clad man, in just a few months, was tortured by cancer to the point that his skin and bones were covered with bones, and the medicine was incurable, and his family was almost ruined, which brought an extremely strong impact picture to Liu Feng, who had almost never faced death.

At that moment, if he didn't have a special ability, I'm afraid he could only watch his relatives die, right?

No matter how high-ranking an official, no matter how successful a businessman, no matter how famous a scientist is, in the face of the dying of life, he can only butcher what he can do.

Therefore, Liu Feng immediately vowed that he must control the true meaning of life!

So, while using his ability to treat his uncle, he carefully observed and analyzed the characteristics of cancer cells.

Theoretically, the causative factors of cancer are closely related to smoking, infection, occupational exposure, environmental pollution, unreasonable diet, and genetic factors.

Its cell characteristics are abnormal cell differentiation and proliferation, uncontrolled growth, infiltration and metastasis, and its occurrence is a multi-factor, multi-step complex process, which is divided into three processes: carcinogenic, carcinogenic, and evolutionary.

Therefore, in view of these triggers and processes, the anti-cancer drugs on the market are mainly divided into four categories.

One is drugs that directly inhibit the growth and proliferation of cancer cells, which can be called tumor cell inhibitors, which are divided into single-target and multi-target inhibitors.

The so-called targets are the pathways in the body of cancer cells, and drugs acting on these pathways can inhibit the production and multiplication of cancer cells; theoretically, the effect of multi-target inhibitors is stronger than that of single-target inhibitors, because single-target inhibitors are easy to develop drug resistance after patients take them.

After all, cancer cells are not easy to mess with, and their 'memory' and 'cunning' are far beyond human imagination! The same method cannot be permanently effective against them!

Therefore, although scientists are constantly discovering various pathways in cancer cells, cancer cells themselves are constantly evolving and shutting down these pathways, which leads to the fact that most of the inhibitor anti-cancer drugs sold on the market are multi-target and multi-channel drugs, which can directly kill cancer cells.

Another class of anticancer drugs is anti-angiogenic drugs.

The so-called anti-angiogenesis is due to the fact that after the growth and multiplication of tumor cells to a certain stage, the previous energy channels are not enough to provide them for division and proliferation, at this time, tumor cells will release an inducing preparation on the normal blood vessels of the human body to induce angiogenesis, which is specially used as their energy channel.

Therefore, as the name suggests, anti-angiogenesis drugs are drugs that can cut off the secretions of tumor cells and induce angiogenesis, which can starve cancer cells to death.

Another class of anticancer drugs is immuno-oncology agents (also known as biotherapeutics).

Because the body's immune system itself has a certain recognition and phagocytosis function of tumor cells, but the camouflage effect of cancer cells is very strong, coupled with the very rapid process of division and proliferation, it will lead to the body's immune function can not play a role.

The mechanism of action of immune agents is to re-awaken or even enhance the immune system's recognition of tumor cells, and then destroy them.

Of course, the last class of drugs is a combination of the above three categories, anti-cancer drugs with multiple functions.

Despite these reasons, no individual or organization has yet been able to develop a drug that completely destroys tumor cells.

In fact, Liu Feng is no exception.

Although malignant tumors all carry the word tumor, it is not actually a disease.

Because the human body is composed of 10 departments (systems), such as the respiratory system, digestive system, nervous system, etc., and each system is composed of several groups (organs), such as the esophagus, stomach, liver, etc. of the digestive system, and each group is composed of several enterprises (organizations), such as the stomach is composed of epithelium, muscles and other tissues.

Finally, each enterprise is made up of individual people (cells), for example, epithelial tissue has a large number of epithelial cells.

Tumors are transformed from normal cells in the body, so there are more types of tumors in the human body!

Up to now, there are thousands of malignant tumors recognized by human beings!

Therefore, there is no single drug that can target all cancers!

Even if it is a tumor immunology drug, it is impossible!

……

Southwest Hospital, the full name of the Southwest Hospital of the Army Medical University.

As the top comprehensive tertiary hospital in Jiangzhou City, it can also enter the top 30 ranks in the national ranking, second only to some general hospitals in Beijing, Modu and Yangcheng.

Therefore, the reputation of Southwest Hospital in Jiangzhou is definitely the most famous, and it has a pivotal position in the entire southwest.

Because Southwest Hospital is also the top clinical trial base in the entire southwest, almost all well-known pharmaceutical companies will get here for clinical trials when they develop new drugs!

Liang Houjie, the academic leader of oncology in Southwest Hospital, chief physician, professor and doctoral supervisor, is currently the chairman of the Oncology Professional Committee of the All-Army Medical Science and Technology Committee, the executive director of the Chinese Society of Clinical Oncology (CSCO), and the chairman of the CSCO 'various' oncology expert committee (the title of 1000 words is omitted below...... He has been engaged in basic research and clinical work of malignant tumors for a long time, and has deep attainments in the diagnosis and treatment of digestive tract tumors and myeloma.

Of course, we are concerned about his position as the head of the oncology specialty group of the clinical pharmacology base.

At this moment, in the office, Professor Liang is holding the meeting schedule in his hand, full of emotion.

About half a year ago, a small manufacturer called Tsingshan Pharmaceutical spent a lot of money to put a clinical trial of an anti-cancer drug in Southwest Hospital.

Originally, with his current reputation and status, it was impossible to pay attention to this kind of small enterprise on the 15th line.

Because whether it is his friends or his collaborators, either experts and professors of the same level are the clinical project leaders of a certain international center, tall!

This can be seen from the more than 200 heavyweight academic papers published in core journals at home and abroad, as well as the various trophies and medals placed at home.

Even his undergraduate disciples are afraid that they will be dismissive of such small manufacturers.

Because domestic pharmaceutical companies, except for the top 10 pharmaceutical companies, which have a little bit of social responsibility and have invested large-scale funds in the research and development of new drugs, most of the other pharmaceutical companies are only concerned about making money, and they simply disdain to engage in research and development.

Whoever votes is stupid!

With the approval for the production of generic drugs issued above, coupled with some interest exchanges that are well known all over the world, you can make money lying down, so why do you have to engage in such a thankless task as research and development?

After all, the cost of developing a new drug is often hundreds of millions and billions, and the R&D cycle is often more than ten years.

So, in fact, the entire pharmaceutical R&D industry is well known.

How many of the tens of thousands of pharmaceutical companies in Dahua have really done new drug research and development?

Liang Houjie doesn't dare to say 99.99%, at least 99.9% of the company's new drug R&D departments are selling dog meat on the head of a sheep, it would be good to be able to do some generic drug projects, what new drugs to do?

Therefore, don't say that he Liang Houjie admires foreign countries, because in the entire pharmaceutical industry, there is a huge gap between China and the West, even if it is another 50 years, Westerners will not develop in the same place, and those guys will not be able to surpass others!

Although 50 years may be a bit extreme, 30 years, there are absolutely no surprises.

"Xuanming, what do you think of this Qingshan Pharmaceutical Factory?"

Sitting opposite Liang Houjie, named Wang Xuanming, is one of the doctors he brings, and he is also his right-hand man, who has very deep attainments in the clinical field of oncology.

"Professor, I have to say that this wild factory that came out of the ravine really scared me a lot!" Wang Xuanming recalled the countless miracles he had witnessed in the past few months, and he was still shocked, "The entire 1,000 volunteer cases are all terminal cancer, and all of them have malignant tumor bone metastasis! However, after using Fuan Ronie for a month, 500 volunteers were cured, and the tumor markers in the bodies of 400 volunteers were significantly reduced, and the cure rate was as high as 90% if they continued to take it for a month!" In other words, only 100 volunteers were not rescued in the end, and these 100 volunteers were not rescued because they were tortured by surgery, radiotherapy and chemotherapy before they were sent to our hospital......

"In other words, the Fuan Ronnie anti-cancer drug developed by Tsingshan Pharmaceutical Factory can cure cancer, and the cure rate is far more than 90%!" Professor Liang continued.

"Yes, although this new drug has only completed clinical trials for myeloma and non-small cell lung cancer, judging from the recent performance of those volunteers, the effect of Foan Roni on gastric cancer and esophageal cancer is also very prominent, and the cure rate is expected to reach 70% As for other types of cancer, they will have some effect to a greater or lesser extent, but due to the time relationship, the number of samples is scarce, and the final result needs to be further clinical; the only two that are sure to be very unsmooth are liver cancer and lymphoma, not only do not have the inhibitory effect, but will accelerate the production and proliferation of cancer cells, which is really puzzling. Wang Xuanming shook his head suspiciously.

"I'm afraid this is due to the mechanism of action of Foon Roney. However, the liver and lymph nodes themselves are important components of the human immune system, enhancing the activity of cells in these places, and the activity of cancer cells is naturally enhanced, and due to the infinite proliferation of cancer cells, the speed is not known how many times faster than normal cells!" Liang Houjie pointed out the truth in point.

Wang Xuanming nodded thoughtfully.

"I really don't know who the leader of the R&D of this pharmaceutical company is, and he can actually research such an epoch-making new drug! For the oncology pharmaceutical industry, his invention is tantamount to a 10-magnitude earthquake, and for the majority of patients, it is tantamount to regenerating parents! This kind of person is a great virtuous saint in ancient times! I really want to see the demeanor of this master!" Liang Houjie, who was sitting in the office and looking out from the floor-to-ceiling window, sighed with emotion.

At his point, money and fame have long been taken lightly by him, and he is happy to know a medical worker who is also highly respected.

Wang Xuanming, who was opposite, knew the teacher's intentions.

I saw him smile and pretend to sigh: "Yes, teacher, I really want to see this master's style! It's just that the Qingshan Pharmaceutical Factory has a very high degree of secrecy about this master, and I went to find out their tone, but those people are unwilling to reveal anything, and I have to wait until today's press conference to reveal the true face of Lushan, and my heart is as anxious as a cat scratching!"

"Hey, no, is there something that your kid is hiding from me?" Knowing the son Mo Ruo's father, and knowing the apprentice is also Mo Ruoshi, Wang Xuanming's expression was seen by Professor Liang on the other side, and he immediately doubted.

"Haha, I know I can't hide it from the professor. Wang Xuanming laughed and told Professor Liang the latest news, "I asked someone to ask the people around Qingshan Pharmaceutical Factory, guess who that master is?"

Which one he still underestimated his teacher's 'desire' for the master.

Professor Liang immediately grabbed his arm, acting like a child, excited: "I don't have the kung fu to guess, tell me quickly, who is it that makes your kid not see the sun tomorrow a second late!"

Wang Huanming: "......"

What's the situation?

You don't play your cards according to common sense!

had to be seriously convinced: "Actually, he is Liu Feng!"