Chapter 309: Vaccines (Part II)
Carl's Applied Healthcare company has been growing smoothly because of its strong partnerships. Its flagship product, Band-Aids, has now become a must-have item for American families, but it is also traveling overseas. After the start of production at the plant of the company's German partner Beiersdorf, the Bondi brand quickly became a well-known brand in various European countries. Beiersdorf also came back to life, and the company was almost grateful to Dade for this cooperation, and Chairman Clawson even made a special trip to California to express his gratitude. This move is a good way to shorten the distance between the two companies. This laid the foundation for the integration of the entire Beiersdorf into the applied health care system in the future.
After the sales of Band-Aids stabilized, it was natural to open up new product lines. This was in Evan's plan. After the board was formed, Evan officially put Carl at the helm of Applied Healthcare. Under Carl's leadership, Applied Health has been on the move, first partnering with several medical schools within the University of California system, and then investing heavily in its own medical research institute and health care research institute, as the name suggests, with the former focusing on medical and pharmaceutical research and the latter developing health care products. By the way, only the latter of the two institutes is in Los Angeles, while the former is located in Sacramento, where the former Chester lab was located.
In the process of setting up the institute, Jesse House, the Warren family's family doctor, made a big difference. If it weren't for his connection, even if the applied health care company had money, it would not be able to find so many qualified medical research talents in a short period of time.
Of course, as we all know, it takes time for any R&D investment to reach output. In the field of medicine, this time is even more uncertain than in other fields.
So, in order not to let the development of the app healthcare company stagnate, Evan once again "had a flash of inspiration" and gave Carl an idea.
The result of this idea is exactly the diaper that Carl's daughter Jenny now uses.
Diapers are a must-have for every new family in modern society, and as an alternative to traditional diapers, it can save parents a lot of trouble, so that they don't have to worry about the child's wet clothes without a change.
Diapers as an idea were not actually Evan's first creation, in fact, the first to try diaper substitutes were the Japanese, for the simple reason that World War II and the lack of natural materials in Japan. And it was the Swede Boris Telm who took a substantial step. In 1942, he invented the two-piece diaper, with an outer layer of plastic pants and an absorbent pad made of wrinkled toilet paper on the inside. However, paper absorbent pads are not widely used because they are too easy to break and debris can get on your child's buttocks.
Of course, Evan's plan does not have this problem, and the absorber he recommends is a polymer absorber. In order to find qualified polymers, Applied Health simply set up a chemistry laboratory and hired several chemists, several of whom were from Germany, who were introduced by Clausen, chairman of Beiersdorf.
With the support of a large amount of money, the R&D cycle of diapers has only passed less than half a year and has achieved results, and the use effect is not bad. After waiting for Evan's approval, the diapers have entered the stage of preparing for mass production. According to the current progress, the official listing is estimated to be in October this year.
Therefore, every diaper used by Jenny at this time is worth a lot of money, because it is not yet a mass product.
After Carl had Jenny, he never doubted the market prospects of diapers. He even felt that diapers were no less valuable than Band-Aids.
But, even so, Carl is still building the company's own R&D team with heart. Because this is the guarantee that the company can continue to introduce new products.
The Medical Research Institute of Applied Healthcare, based on the advice of experts such as Dr. Evan and House, and the research bias of the recruited personnel, identified several major research priorities, namely heart drugs, high blood pressure drugs, diabetes drugs, and polio vaccines.
Needless to say, the vaccine that Carl came to Evan today to ask for was the polio vaccine.
This research direction was assigned by Evan.
Speaking of polio, it can be said that in this era, it can be said that it has changed color. This acute infectious disease caused by the poliovirus, which can cause serious harm to children's health, has caused huge losses to the United States, and the biggest victim is none other than the former President of the United States, Roosevelt. With the end of World War II, the United States ushered in a post-war boom and entered a period of rapid population growth. As the number of babies increased, the number of polio victims began to break out. In 1946, more than 20,000 cases were reported nationwide, and by 1950, that number had doubled.
If this continues, more and more children will be victimized.
Faced with this situation, mothers in the United States decided to declare war on polio. They have tried to solve this problem through various means, including setting up funds and lobbying government departments.
To date, a fundraising campaign called "Polio Mothers Action", which began last year, has raised tens of millions of dollars and is still unstoppable.
This action was the reason why Evan persuaded Carl to make polio a key focus of the institute.
Evan not only gave advice, but also recommended Carl to an expert in the field. This person is none other than the Sabin that Karl just mentioned, named Albert Sabine.
Polio is caused by a virus, and the best way to solve it is to use a vaccine. This work has already been done after the cause of polio has been identified. According to the type of vaccine, the current research is divided into two routes: one is an inactivated vaccine and the other is a live attenuated vaccine. The former is named after Jonas Salk of the University of Pittsburgh. Salk), whose advocate was Albert Sabine of Cincinnati.
In principle, inactivated vaccines are a better choice than live attenuated vaccines, both in terms of safety and research difficulty. And that's exactly why Carl came to Evan today.
He wondered why Evan chose to support the latter's research.
"There are three reasons...... Facing Carl's questioning, Evan replied unhurriedly: "First, Salk not only has the support of the National Foundation, but also has ten pharmaceutical companies watching, and it is difficult for us to intervene;"
"Second, the production conditions of inactivated vaccines are very demanding, we lack the relevant experience and technology, of course, you can say that it will definitely take a short time to successfully develop a vaccine, which is enough time for us to prepare the production conditions. Well, if that's what you think, then assume I didn't say this;"
"Thirdly, and most importantly, I think Sabine's route has greater safety. ”
Evan dared to draw this conclusion because he had "history" as the basis for his judgment.
"Although Salk's vaccine was one step ahead, because of the underestimation of the difficulty of inactivating the virus, the vaccine became a virus, and a virus outbreak was artificially created, which is known as the 'Carter tragedy'. ”
"I don't want my company to be involved. ”