At this time, it was already a little late, and Yang Zhenghe was the only one sitting on the sofa in the living room, he buried his head in his two knees, his hands were deeply inserted into his hair, and the whole person shrunk into a ball like a newborn cocoon.

Ren Pingsheng dragged his heavy steps to his uncle's side, patted his back gently, only to find that the man had been trembling, Ren Pingsheng sighed, shook his uncle's shoulder and said, "Uncle, wake up, are you okay?" ”

Yang Zhenghe picked up his head from his knees, he took off his glasses, there were tears left in the corners of his eyes, obviously he had just cried, his gray hair was messy like a grass nest, the elegance and handsomeness of the past were gone, and the wrinkles on his face were deeper, and his uncle at this time was far more fragile than his age, more like a helpless child.

"Xueping, Xueping, she is too bitter, but I can't save her. Yang Zhenghe muttered to himself.

"There is a way, there is a way. Ren Pingsheng muttered to himself, he was not just comforting his uncle.

Ever since he learned of his aunt's condition, he has been desperately using the memory bank in his head to find a possible cure from the memories of his past life.

Although Ren Pingsheng did not study medicine in his previous life, and did not have many friends with doctors, he read a lot and dabbled in various fields, especially high-tech information, although it had little to do with his work in his previous life, but he browsed a lot in his spare time.

So he vaguely remembered that there was a treatment for advanced non-small cell lung cancer, and that was targeted therapy.

Targeted therapy is a new application of genetic testing technology in the therapeutic field, and as the name suggests, it is a type of therapy that targets the specific targets of tumor cells (whether the gene is mutated or not) to attack them.

By interfering with the molecules required for the proliferation and differentiation of tumor cells, some drugs can directly cause apoptosis of tumor cells, or indirectly stimulate the immune system to recognize and kill tumor cells.

To put it simply, the difference between targeted therapy and chemotherapy is that targeted therapy is a "guided missile" that targets a small number of cells and does not harm other non-target cells, while chemotherapy is a carpet bombing that kills harmful cells while also harming innocent cells.

Compared with chemotherapy, targeted therapy is more precise and targeted, which can be called "high efficiency and low toxicity", which not only exerts stronger anti-tumor activity, but also reduces the damage to normal cells, effectively prolongs the survival time of cancer patients, and provides patients with a quality of life close to ordinary people.

Although targeted therapy has many advantages, not many people really use it in China, the main reason is that it has a natural shortcoming, and it is also the most fatal shortcoming, that is, it is too expensive.

Taking Ren Xueping's lung cancer as an example, the most common driver gene detected so far is the EGFR gene mutation.

In 2004, two research teams in the United States announced that they had discovered that non-small cell lung cancer has an epidermal growth factor receptor (EGFR) mutation driver gene, which is located on the short arm of human chromosome 7.

The incidence of this epidermal growth factor receptor mutation in East Asian populations, especially among Chinese, is particularly high, accounting for about 30% of all non-small cell lung cancers, and Ren Xueping is one of them.

At present, the pharmaceutical industry has developed targeted drugs that can target EGFR genes, and the molecular targeted drug Terrissa (gefitinib tablets) pioneered by Astraton Pharmaceutical in the United Kingdom has been developed.

This drug has just been approved by the US FDA in 2003, mainly by inhibiting EGFR autophosphorylation and blocking conduction, inhibiting the proliferation of tumor cells, and achieving targeted therapy, which is the best treatment option for the treatment of advanced non-small cell lung cancer.

However, due to the restrictions of drug patent protection, at present, only imported Tagrisso, the original product of Astraton Pharmaceutical, can only be purchased in China, and the price of a box of 10 tablets is about 5,000 yuan.

According to the way of taking a course of treatment (1 tablet a day), it costs 15,000 yuan for 1 month, and 180,000 yuan for 1 year, which is already a down payment for a house.

This way of eating, not to mention that a well-off family can't afford it, even a little rich with a little money will go bankrupt, let alone Ren Xueping's family, who only rely on salary income, so after listening to Ren Pingsheng's introduction, the little hope that had just been ignited was instantly shattered.

In order to alleviate the pain of his beloved wife, Yang Zhenghe not only used up all the family's savings, but also borrowed a lot of debts from relatives and friends, and even put the house that was still repaying the loan on the market to sell.

Yang Zhenghe has obviously exhausted all his strength, he is exhausted, but he is still powerless to save his lover, Ren Pingsheng can feel his pain and despair, there is nothing more sadistic than watching his lover suffer and die, but he can't do anything more sadistic.

"Uncle, don't worry, let's figure it out together, my aunt and her Ji people have their own natural appearance, and they will get better. Ren Pingsheng seemed more mature at this time, and comforted the elder in front of him softly.

"No, it's all my fault, it's me who has burdened her, I love myself more than I love her, I can't let go of my self-esteem, I don't care about fighting for benefits, and as a result, I don't have any ability to help her, I can only watch her suffer. ”

Yang Zhenghe grabbed his hair hard, as if he wanted to punish himself by scratching his hair.

"Xueping has suffered with me all my life, all because of me......"

Looking at Yang Zhenghe's self-blaming words and actions, Ren Pingsheng was silent, this was the first time he had witnessed the cruelty of the real world since he was reincarnated.

As my uncle said, if their family is rich, they can let my aunt receive the best treatment.

If their family is very powerful, they can also arrange the best medical resources for their aunt.

If you have no money and no power, you can only watch your relatives die under the torture of illness.

He also thought that if he married Zuo Xiaoxiao in his previous life, and Zuo Xiaoxiao would also be seriously ill one day, he would definitely fall into Yang Zhenghe's current situation, because Ren Pingsheng, like Yang Zhenghe, in his previous life, did not have the ability to save his lover.

In this way, Zuo Xiaoxiao left herself in her previous life, but it was a better choice for each other.

But everything in front of him is different, Ren Pingsheng is a traverser who is reborn with the memories of his previous life, he will not allow this to happen, he not only wants to save his love with Zuo Xiaoxiao, but also to save his aunt and uncle, and save all the people he values.

Ren Pingsheng secretly made up his mind that if he needed to change his life against the sky, then start from this moment.