93 Another chance miracle
The other three reviewers also agreed to let Ragnar Burnett do the experiment. Whatever their identity, the head of the Department of Chemistry and Medicinal Chemistry at the University of Oxford, is known as the head of Pfizer's global research, chief scientist, and head of the research department,...... , how bullish \1 force. Ragnar Burnett is a Nobel laureate.
"Good. Ragnar Burnett nodded.
Ragnar Burnett donned protective gloves for the experiment. Protective eyewear. Wearing a white coat, a test tube contains the most terrible live HIV virus. No matter how you protect, you can't be too careful. He took the test tube containing the fragrance from Dai Xinliang's hand. and the test tube containing the HIV virus, inserted into the test tube rack.
The experiment began.
......
with this. Pfizer across the ocean. Roche, Merck, Novartis, these four companies, and the Chinese government are also looking forward to the results of the demonstration experiment.
Dai Xinliang submitted his paper to Nature Review: Drug Discovery, and six people knew about it, and the first reviewer of the paper, John Keynes. and 5 reviewers.
These six people are implicated in these four pharmaceutical giants. Sean Claudeford is simply Pfizer's chief scientist and head of the research department.
So, these 4 pharmaceutical giants know the news.
The northern and southern hemispheres alternate day and night. In China, it's daylight at this time. It's night in the United States. Probably none of the executives of these four pharmaceutical giants can sleep.
Indeed, according to the United Nations, 39.5 million people worldwide are living with HIV. Plus people who hide that they have HIV. This number is more than 50 million. And even more. A drug that can cure AIDS produces benefits that even four global pharmaceutical giants tremble. If an AIDS patient is cured, the cost is $1. That's 50 million multiplied by $1. Executives of 4 pharmaceutical giants will count.
Ragnar Burnett took a slide and placed it on the bench. Took a straw and picked up the tube containing the HIV virus from the test tube rack. Pipette into the tube. A few drops of liquid were sucked up. Then, drop 4 drops on the glass slide.
Move the slide under the microscope. The display connected to the electron microscope shows the microscopic image. In the microscopic image, it is densely spherical and has a cone-shaped material distributed on the surface. There is a dense phobia, and everyone present, including Zhou Yun, knows that it is the HIV virus.
Ragnar Burnett then removed the slide from under the microscope. THEN, A FEW DROPS OF GREEN LIQUID WERE ASPIRATED FROM THE TUBE CONTAINING THE FRAGRANCE USING A GRADUATED PIPETTE AND ABOUT 0.3 ML WERE DROPPED ON THE GLASS SLIDE AND MIXED WITH THE HIV VIRUS. Ragnar Burnett then moved the slide under the microscope again.
In addition to Zhou Yun, and Dai Xinliang are a little relaxed. Everyone's eyes are glued to the display. The face is expressionless.
On the display, you can see it clearly. One by one, the HIV virus protein skin capsid ruptures. Inactivity. About 15 minutes passed. All HIV viruses are inactive. All were killed.
laboratory, there was a huge round of applause.
"Clearly, the experimental argument was successful. There is no reason to refuse your paper to be published in Nature Review: Drug Discovery. Congratulations. ”
"There is no doubt that this is a Nobel Prize-worthy discovery." The Nobel Prize beckons to you. This year, next year, not until 2013 at most, the two of you could jointly receive a Nobel Prize in Medicine and Physiology. Congratulations in advance. ”
Zhu Ziping said, "The hanging heart can be put down." Congratulations. You are fighting for the Chinese. Tu Youyou won the Nobel Prize in 2015. He was awarded the Nobel Prize in Medicine and Physiology for his creative development of new antimalarial drugs, artemisinin and dihydroartemisinin, which achieved a 100% inhibition rate against Plasmodium. Mo Yan is 2012.
"I can talk about the process of discovering the fragrance. I think they're interested in that as well. Sean Claudeford said.
"Indeed, I am very interested in this. Ragnar Burnett said.
......
"Then let Zhou Yun say. Dai Xinliang said.
"Good. Zhou Yun said, "In March last year, I went to Changbai Mountain to dig ginseng. A small shrub was found in Changbai Mountain. The small shrub has kidney-shaped, small red thumb-sized fruits. A flock of birds pecks at the fruit. I drove away the birds. Then, the fruit was picked. Put it in an aluminum lunch box and bring it back.
Since this fruit has a fruity fragrance. The aroma is intense. Therefore, I named this fruit fragrant fruit. The small shrub is named fragrant wood.
I took the fragrant fruit to the plant composition analysis laboratory of Jiang\1 West Agricultural University to analyze whether it is toxic and the ingredients it contains. It was inadvertently found that the fragrant fruit contained an active ingredient that was not known. I named it Fragrance. Then, the well-known process is constantly screened for the medicinal value and efficacy of the fragrance. Finally, when the HIV virus is screened. I didn't expect the fragrance to hit it off with the HIV virus. ”
"Another chance miracle in the history of great drug discovery. This is true for penicillin, this is true for Bailangduoxi, and now the same is true for fragrance. Sean Claudeford said.
"Yes, indeed. Zhu Ziping nodded.
"If you win the Nobel Prize for your fragrance. You are one of the easiest winners in the history of the Nobel Prize. Ragnar Burnett joked.
......
Out of the lab. Retrieved his phone in the guard room.
Zhu Ziping sent a text message. "Humanity has conquered AIDS. ”
Ragnar Burnett, Sean Claudeford, and five others did the same thing. A text message was sent to someone who was waiting for news across the ocean, and the text message was the same, "Humanity has conquered AIDS. Wells Campbell added a few more words, "Another chance miracle has overcome AIDS." "As the radio waves cross the ocean. Executives of the four major pharmaceutical giants Pfizer, Roche, Merck & Co., and Novartis received the news. Very quick to respond and come up with a strategy quickly.
However, at 2 p.m. that day, China's Xinhua News Agency posted a micro-blog post. A piece of good news, Dai Xinliang, a professor at Jiangxi \1 West Agricultural University, and Zhou Yun discovered that fragrance can completely kill the HIV virus. There is hope that AIDS patients will be cured. At this time, the negotiation team sent by the four pharmaceutical giants was still on a plane to China.
Xinhua News Agency's micro-blog stunned them all at once. Other pharmaceutical companies that realized it were also stunned. AstraZeneca in the UK, Gilead in the US, Merck KGaA,...... , and even China's Hengrui Pharmaceutical, suddenly became crazy.
Executives from the world's pharmaceutical giants flew to China with large negotiating teams.
At the same time, at the same time, the information of Dai Xinliang and Zhou Yun was constantly summarized into the hands of the negotiation team who were still on the special plane.
Dai Xinliang. Jiang \1 West Agricultural University Professor. Director of the X Pharmaceutical Institute.
He presided over the research of fragrance. The company of X Pharmaceutical Research Institute is Qingxiangguo Biopharmaceutical Co., Ltd. And Zhou Yun holds 100% of the company's equity. Therefore, Dai Xinliang is not important.
Qingxiangguo Biopharmaceutical Co., Ltd., except for the X Pharmaceutical Research Institute, is a shell company, this company did not have any value before, but now it has value, this company is more valuable than any pharmaceutical company in China. Because, it has a patent for fragrance compounds and patents for use. This is also the purpose of the executives of the world's pharmaceutical giants with a large negotiation team to lead China.
Although the fragrance fruit biopharmaceutical company has patents for fragrance compounds and patents for its use.
But, it compares to the world-class pharmaceutical giants. It doesn't have a huge global pharmaceutical sales force. Sell the medicine to hospitals and pharmacies. It does not have the strong combat effectiveness of public relations governments, hospitals, drug regulatory departments, and drug marketing approval agencies.
What's even more deadly is that it has no way to infringe on drug patents.
For example, the biopharmaceutical company lacks a patent, a method patent.
India only needs to get a tube of the fragrance injection, and they don't even need to modify the pharmaceutical process to make a copy of the drug.
Generic drugs are identical to patented drugs in terms of dose, safety, potency, efficacy, quality, and indications.
While the biopharmaceutical companies were still trying to expand the market, Indian pharmaceutical companies had already sold generic versions of the fragrance to the world. Generic drugs, in turn, have robbed the market for patented drugs. India is not so good in other respects. However, the world pharmacy is not called for nothing.
Therefore, the biopharmaceutical company can only authorize drug patents. Or simply sell pharmaceutical patents.
Soon, the negotiation teams issued instructions to focus on collecting information on the week's movements.
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