Chapter 65: Immune to Attack
"Ah...... Ah......h
With a terrible scream in the ward, a layer of cold sweat broke out on Dean Saito's forehead. He waited anxiously in the observation room outside the ward, not knowing what to do with the emergency situation in front of him. ”
"How's it going?"
When Hideki Kalai hurriedly pushed open the door of the observation room next to the ward, Eisaku Saito was often relieved, he turned around, pulled Hideki Kalai to the glass curtain wall of the observation room, and then pointed to Hikozaburo Ueno on the hospital bed and said:
"Look, it's been like this since I sent it yesterday, didn't you tell me that this is human tissue regenerated from autologous cells, why...... Why is there such a severe rejection now?"
Eisaku Saito grabbed Hideki Kaais by the collar and questioned him unceremoniously.
"Rejection? This is impossible? How can there be rejection? The cells we use are originally Ueno-sama's!"
"Look, this is a report from the pathology department, and now Mr. Ueno's immune system is frantically attacking the implanted retina...... It's not a rejection reaction ......"
"It can't ......"
Kaais Hideki stiffened his mouth, and then snatched the diagnostic opinion sent by the pathology department and checked it carefully, seeing the indicators listed on the report, Kalai Hideki's face immediately showed a look of despair.
"See, this is the rejection that you claim will never occur, and now it is actually happening to the patient...... Professor Calais, forgive my faux pas, you are not a doctor at all, you don't know that rejection can also occur in autologous cells, the immune system attacks its own healthy tissues without distinction between friend and foe, this disease is not an impossible thing, lupus erythematosus, rheumatoid arthritis and other diseases The cause of which is still an unsolved mystery until now......
Hearing Saito's reprimand, Hideki Kalai immediately understood how ridiculous what he had just said could not be. Yes, although the transplanted tissue is derived from the patient's own cells, it is ...... STAR stem cells that have been reversed by the virus are not necessarily considered their own by the immune tissues in the body. Now, Ueno's immune system is in a brutal struggle with the newly transplanted retina, and if this continues, the patient's eyes may not be saved.
"Professor, I don't think STAR stem cells are ready for clinical trials yet, and I recently studied the possible risks after STAR stem cell transplantation, although the probability is very small, but ...... I found that these tissues were tumorigenic, carcinogenic, and at risk of causing an overreaction of the immune system, Professor ...... I'd like to take a closer look at these potential problems......"
I don't know why, Hideki Kalai suddenly can't listen to a word now, and his mind keeps replaying the words that Asari Yoo told him before he died, STAR stem cell therapy is not a 100% safe treatment, in fact, there is absolutely no 100% safe treatment in the world, but ...... If there is only a small risk of this, Hideki Kalai thinks it's not a big deal, so ...... Before submitting the clinical trial of STAR stem cells to the Ministry of Health, Labor and Welfare, both Hideki Kalay and Sumitomo Pharmaceutical felt that it was necessary to temporarily conceal the defects related to STAR stem cells so that the products applying this technology could be marketed as soon as possible. Pity...... I didn't expect such a serious problem to arise after the first transplant......
"What should I do if I have such a severe overrejection reaction? Now Hideki Calais doesn't know what to do. Because he studied cells rather than the human body, Hideki Kalai had already returned to his teacher what he had learned about the immune system back then. As Eisaku Saito explains, the technology he invented can be applied to treat many terminal diseases that clinicians can't handle, but ...... He himself had never treated a single patient himself......"
Seeing that he asked for a long time, but Calais Xiu was still unable to give a reasonable explanation, Saito Eisaku couldn't help but feel more and more worried, it seems that this professor can't come up with any good countermeasures, so ...... How do you deal with it......? Is it really the same way that immune system disorders are treated?
"Dean Saito!
Just when Eisaku Saito was hesitating, Shiori Tokunaga, who had been standing aside and quietly observing the development of the situation, suddenly spoke. I saw her gently walk behind Dean Saito, then bowed her head and saluted the other party, and then reminded the other party in a low voice:
"Dean, what if we treat patients according to the diseases of the immune system now?
"Ah...... This one...... I have never dealt with such a patient and I cannot guarantee the results of the treatment. ”
"So...... Can patients still see now?"
"It's just the beginning of the attack, so there's no room for irreversible damage in terms of vision......
"So...... What if we use drugs that suppress the immune system? Can we save our eyesight?"
"Suppressing the immune system, this can only solve the immediate crisis, Bin is not a long-term solution!"
"Dr. Saito, what we need to solve is the immediate crisis, as long as we can keep the patient's vision until the day when the STAR stem cell-related drug is approved for marketing, we will achieve the goal of clinical trials. Seongnam General Hospital will be the only hospital in Japan that can perform regenerative retinal transplants in the world......"
"But...... In that case, the patient will not have even the slightest resistance in his body, and he may have to live in a sterile ward for the rest of his life......"
"Dean Saito, I believe ...... The problem at hand is only a temporary small difficulty, as long as we buy some more time for Professor Calais, it may not be long before the problem at hand will be satisfactorily solved!
Hearing that Shiori Tokunaga had given him a decent step, Kalay Hideki could only survive for a while, so he raised his head and pretended to be calm and said to Saito Eisaku:
"Don't worry, Mr. Saito, I will definitely find a solution to the problem as soon as possible, please trust me......"
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