Chapter 348: The Laboratory of Terror
[The rigorous scientific research materials on brain organoids in this chapter are all from MIT Technology Review and Scientist magazines, and are not original fabrications of the author, special annotations.] 】
As soon as he walked into Rudolph's laboratory, Zhou Cunguang's eyes widened.
He has been in the organization for more than half a year, to be honest, he has traveled all over the country, in order to learn the language, he has been to several countries, and there are teachers of four languages around him all the time, 24 hours of indoctrination, and he has also seen the world.
But Rudolph's lab was different.
Zhou Cunguang also knew that this was the world's most mysterious laboratory before he came, this is not a question of whether he has seen the world, it can be said that even the presidents of various countries want to come here to see, but they can't.
Zhou Cunguang, who came here, was excited, he had countless fantasies about this laboratory, he had thought about all kinds of high-tech, and he had also thought about countless forms of black science when he was working, and even drew on paper the appearance of robots that might exist.
But the scene in front of him was beyond his imagination.
Closed his eyes tightly, stretched out his hand and pinched the bridge of his nose, only to feel that the vision in front of him was a little dizzy, and after this, he opened his eyes again, and Zhou Cunguang was pestled there like a wood carving.
"Don't be afraid, the things I need to do experiments can be more advanced by relying on their human brain organoid technology. Rudolph said this, his jaw was slightly raised, and he also looked at the wall, and unlike Zhou Cunguang's frightened eyes, Rudolph's eyes sparkled like stars.
It was this kind of look, this kind of eyes full of incomparable love for scientific research, that made Zhou Cunguang recognize Rudolph in an instant.
It's just that......
Zhou Cunguang gasped, not daring to look at the wall.
"If you're not a child, it's impossible to come in, this is a top-secret place, don't move, I'll look for the medicine box there, you go over there to see if there's anything to eat, I remember it." As soon as Rudolph entered the laboratory, he seemed to have forgotten about Zhou Cunguang, and after chattering a few words, he actually sat down in front of the monitor and watched.
Zhou Cunguang looked around, this laboratory is really big, it can be described as magnificent. Unlike the experiments of scientists he had seen in China, the area was ten times larger, and it could be said that the laboratory of a department was not as large as Rudolph alone.
In addition to being the only one, there are several robots parked around, which is also different.
Rudolph is right, if it weren't for Zhou Cunguang being a 'child', he would not have been able to enter such a top-notch laboratory, you must know that he didn't enter Professor Zhou's laboratory. In the distance, you can see several glass bottles, and there is a mist inside, and I don't know what is there.
His eyes looked at the wall, and he immediately ducked again.
It's so crazy, it's really crazy.
Walls full of human heads......
I saw that the huge bookcase that reached to the ceiling was full of glass bottles, which were soaked in an unknown liquid, and the glass bottles were just the size of a person. Some have faces, some have only half of their faces, some have their faces peeled off, some have been cut in half, and more are just a bunch of brain tissue soaked in them. There are some introductions posted at the bottom of each glass bottle, which are too far away to be seen clearly.
It's not that Zhou Cunguang hasn't seen the human body title, and he has imagined the appearance of brain tissue, but he has never seen hundreds of such human brains.
There are hundreds of them! There are two walls that are nearly three meters high, and each glass bottle is full of these things, and it looks like hundreds of people are staring at themselves.
As you can see from the hair, there are old people, men, women and children.
And the black and gray ones that are soaked in small bottles, what are they?
It's crazy, it's really crazy.
Zhou Cunguang couldn't help but put his legs together tightly, there was an illusion that he wanted to go to the toilet, this illusion was only like this when he was extremely nervous, he quickly looked away again, only to feel numb all over his body, and his throat was itching, and his stomach was churning.
Wow......
He suddenly vomited, but fortunately there was a garbage can nearby, but it also spilled a lot to the ground, and a robot in the distance immediately slid over to clean it, but Rudolph, who was sitting in front of the microscope not far away, seemed to be unable to hear everything around him, and still sat there testing something.
Zhou Cunguang slowed down, let himself stabilize his emotions, and after a quick look around, his eyes fell on the label attached to the glass bottle of human brain tissue in the bookcase, and walked over quickly, wanting to open the bookcase to take a look, but found that it just looked like a bookcase, but in fact it was a huge thermostat, just made in the shape of a bookcase.
It can't be opened at all.
On the left side there is something resembling a fingerprint*, a cassette with a layer of cassette, and it seems that the only one who wants to open this thermostat is Rudolph.
Lying on the glass and looking inside, I saw that there were some things written on the glass bottle that Zhou Cunguang couldn't understand, such as totipotent stem cell, TSC, and pluripotent stem cell.
"Illegal approach! Illegal approach!" Xu is Zhou Cunguang pasted the whole glass too hard, and suddenly the thermostat issued a warning, and the sudden sound and the head of the cabinet made him tremble.
"Don't move!" came a very stern voice.
Zhou Cunguang turned his head to look, only to see Rudolph wearing glasses, his face full of anger and seriousness glaring at him, as if a fierce beast was about to protect his cubs.
"I ......"
"Come here, I told you you not to move!" Rudolph grabbed Zhou Cunguang and dragged him aside, which was completely different from the kind face he had to him before, he was very fierce, he stretched out his hand and pushed his glasses: "These are my treasures, you don't have to be afraid, you don't have to be curious, it's just something to be used when researching." ”
"These are you...... Cultivate...... Cultivate...... Cultivated, it's still ......" Zhou Cunguang's voice trembled slightly.
If these were cultivated by him, it would be fine, but they don't look like they were cultivated left and right.
Although the field of human brain organoids is advanced and ordinary people do not understand, they also know that this is to solve some problems that arise inside the brain, which leads to what results. For example, why is Zhou Cunguang a dwarf, is there a problem with the pituitary gland of the brain, what is the specific problem, and what drugs are needed for treatment?
At present, the scientific community is unsolved about this, which is also the reason why Zhou Cunguang understands that there is no cure for his disease.
How to solve this dilemma?
Traditionally, a dwarf's brain is detected and dissected to see what went wrong. But the brain is so complex, even if you see something wrong, what is causing it? Where is the problem in brain development? Is it a problem with the pituitary gland alone, or is it caused by the slow influence of other brain structures?
These problems are difficult to achieve by dissecting a dead brain.
Only when we trace the source of these problems and discover what the cause and which cells cause the occurrence of dwarfism can it be possible to develop drugs for research and development. Developing a drug is a different group of scientists, and the scientists who develop the drug have to find out why first.
These are interlocking.
In the villa area, the world's most mysterious huge research room, the brain organoid research room is next door to the laboratory of drug scientists.
Going back to the previous question, these problems are difficult to achieve by dissecting a dead brain, so how can this be achieved? This brings us back to the direction of Rudolph's research: brain organoid research.
Brain tissue is cultivated artificially through cell culture, and the brain is artificially conceived from the tiniest stage, so that you can see what is going wrong. For example, by obtaining cells from patients with dwarfism and cultivating organoids with the same characteristics as the patient's brain, researchers have cultivated some of the organoids by replacing the defective protein that is related to the backbone face of the disease.
Of course, this is easier said than done.
Can......
Rudolph looked at the human head on the wall, and only felt trembling in his heart, he remembered that the organization gave him information before he came, saying that Lancaster had published an article saying that there was no need for craniotomy to remove the human brain for cultivation, but only needed to obtain some cells from the skin, and then after cultivation, he could cultivate a brain organoid with a shape and function similar to his own brain.
This made Zhou Cunguang feel that the research on human brain organoids was not so bloody, and he just needed to take some human skin.
At that time, Zhou Cunguang felt incredible when he first saw this, and he also felt full of pride, is the technology so developed now? It only takes a little skin to cultivate a brain similar to you? Although it is not a completely usable brain, but since the brain organoids can be cultured by taking cells from the skin, how can there be so many dissected brains here?
"Of course I didn't grow these, don't you see that there is still skin and hair here? The research I did was to cultivate human brain organoids, which are cellular tissues. Rudolph obviously felt very ignorant and ridiculous about Zhou Cunguang's question.
"So these are ......"
"People, when they come, they are all fresh heads, right?"
A burst of cool air hit, as if passing by the big freezer with yogurt in the supermarket, so Zhou Cunguang instinctively took a step towards the bookcase, trying to avoid this cool air, but in vain.
The coolness came from his heart, not from this bookcase-like thermostat.
"I've heard that you only need to take a little skin from a person to get the tissue that cultivates human brain organoids, so why do you need it...... Need...... Need to ......" Zhou Cunguang didn't dare to look at the soaking heads on the wall, his voice was a little quieter, it was obvious that he could hear the fear in his heart, he swallowed his saliva with difficulty, maybe it was a psychological effect, and he always felt that the saliva he swallowed seemed sticky, like the taste of uncooked pig brains that he had eaten.
"Of course we need heads. Rudolph was once again amused by Zhou Cunguang's ignorant question: "From the tissue that can be made from human skin to make organoids, a large number of human heads have been studied in the middle, which is indispensable in the laboratory; besides, the study of human brain organoids is a long road, and the study of human brain anatomy is a routine state." ”
Behind scientific research, there must be animal experiments. It is no secret that mice or rabbits are used for research, and large numbers of animals are used for scientific research. In addition to animals, the human body is also a treasure snatched by major hospitals and scientific research sites.
A good medical university, how many bodies are stored in the school is an important indicator for medical students to conduct research. Not to mention the research institutes, where scientists dissect the human body, analyze the human body in order to benefit humanity in the future.
"These ...... But baby, how can you grab so many fresh heads for research outside!" Rudolph shook his head disdainfully: "It's good to have five fresh corpses in a laboratory every quarter, and there are not many people who voluntarily donate their bodies for research these days. ”
As he spoke, he heard the sound of the door opening.
A door opened, a section of railroad tracks surfaced from the ground, and several incubators slid in at a rapid pace.
"Tsk, look, there's a steady stream of fresh corpses here! Wonderful! Wonderful!" Rudolph flew towards the incubators, a happy smile on his face, and exclaimed, "Great, great, there are five children today, five!
He lay down on the incubator and turned his head.
The smile is full of happiness.
[The scientific research description of this chapter, I read more than 30 kinds of scientific research materials before writing, you can take it to chat and pretend to be forced, but don't ask me to be crazy at the speed of Xiaobaiwen, thank you, it's going to end soon.] 】