A chat at a dinner party did not prompt Yang Rui to make a decision. Pen & Fun & Pavilion www.biquge.info

Cloning Dolly the sheep is an achievement of genetic engineering, and although genetic engineering belongs to biology and is a large category in biology, for biological researchers, the span between these two regions is already very large.

Of course, the ion channel and genome project that Yang Rui is doing now has a lot to do with genetic engineering in theory, but this is only a big profit, and it takes real work to make a cloned embryo sheep.

Yang Rui accompanied the exhausted grandfather back to the hotel, but he couldn't sleep.

The next day, after sending his grandfather to his comrades-in-arms' house, Yang Rui returned to the laboratory and arranged for the scientific research dogs to search for information as soon as possible.

Regardless of whether you do it or not, the first step in understanding a field is always to search for information.

A few scientific research dogs put down their work without any choice and began to search in the sweaty data room and library.

The library of Peking University is still in the form of cards, with book titles and book numbers and brief descriptions of the contents recorded on the cards, and the scientific research dogs first search for cards according to various initials, and then rummage aimlessly in the natural science library.

At the same time, some people took out past journals and looked at them one by one.

Doing scientific research is like this, most of the work is repetitive manual labor, and a job that can be done by a random college student, but the best and fastest to do it is always the smart person, so that such a job, honest, down-to-earth, serious and clumsy children, is still not popular.

Because the library is endless, you always have to think of a way to simplify your work, and sometimes, it is better to increase the probability of luck than to follow the steps.

After all, research is not an isolated job, and competitors are everywhere.

That night, Yang Rui saw the figure of the competitor.

Dr. Wilmut's name appears in the fact sheet, unsurprisingly.

In later generations, the name of the father of cloned sheep has long filled the ears of biology students.

But in 1985, Wilmut was still an obscure young researcher, and the reason he appeared in the data sheet was that he was the first to breed a calf from frozen embryos, and the time coordinate is 1973.

Yes, as early as 12 years ago, Wilmut had already made the embryo transfer technology that the head animal husbandry company wanted, and he went one step further to transfer frozen embryos.

The difference between frozen embryo transfer and embryo transfer is like the difference between frozen egg IVF and IVF. As early as the 90s, a large number of IVF technologies have been used in China, but after egg freezing, the technology of IVF is still only carried out by a few hospitals until the 10s, which can be seen from the technical generation difference between the two.

Of course, the frozen embryo transfer done by Wilmuller is the first case, and it is also a laboratory product, which is still some way from commercialization.

However, in terms of his achievements, he is actually not weak.

In '73, Wilmuller graduated with a Ph.D. from Cambridge University. With such a result soon after graduation, it is no wonder that in the 80s, he had the opportunity to run a laboratory.

Such a speed is also very fast in Europe and the United States.

Yang Rui has the impression that Wilmuller also had the idea of cloning since the late 80s.

The reason for this impression is that the prerequisite for mammalian cloning, the way in which the enucleated egg cells fuse with the nuclei of early embryonic cells using the method of electrical impulses, was created by Willadsen in 86 and is certainly in rudiments now, but it has not yet been announced.

With this approach, Vilmuller would have a basis for cloning.

However, for scientific research, a year is already a fast time.

The next year, Wilmuller probably had the idea of cloning mammals.

In other words, if Yang Rui also wants to do cloning, he will have to compete with Wilmuller for scientific research.

This is not an easy task.

It's not that Wilmuller is so powerful, Yang Rui now has a very strong ability to obtain resources - Nobel Prize nominations are no joke, coupled with the profitability of PCR and deferiprone , he can even get direct sponsorship from banks or pharmaceutical consortiums, and with sponsorship, there is naturally capital to compete.

However, the gestation period in mammals is certain.

You've done the nucleus transplant -- it's a crucial step in cloning, but you'll have to wait months for the mother to be able to give birth to a lamb or some other animal.

Yang Rui didn't know how many times Vermuller had tried, but he knew very well that even in the 10s of the 21st century, cloning was still a very delicate, complex and luck-intensive work, requiring a capable team to work together for a long time.

Can Ion Channel Labs, or Sinovel Labs, do that?

Yang Rui really didn't know.

Yang Rui's hesitation did not last for a few days.

When he led his grandfather to climb the Great Wall, visited the Ming Tombs, went to Tiananmen Square again, and paid homage to Chairman Mao's portrait for the second time, Yang Rui's BP machine rang.

Now, there are obviously more signal stations in the capital, and Yang Rui's BP machine has finally come into use.

However, there are not many people who have seen the BP machine, and the crowd queuing up to move forward has paid attention to Yang Rui.

Yang Rui looked at the number on the BP machine, but he didn't know it, thought about it for a while, and put it down.

Comrade Yang Shan's eyes were bright, he waved his hand, and said, "I'll just line up by myself, and you can go and get busy with yours." ”

Yang Rui shook his head: "It's not a phone from the laboratory, it's not a phone from the school, it's the same if you call it again." ”

The queue in the memorial hall was very neat and solemn, but after all, it was a crowded queue, and Yang Rui didn't care about leaving his grandfather's side.

Yang Shan is not the kind of polite person, seeing that Yang Rui is unwilling, he does not force it, and continues to line up quietly.

"Leader, do you need to use the phone?" A staff member of the memorial hall quietly came to Yang Rui's side and startled him.

"You walk without a sound?" Yang Rui's heart beat fast, what kind of place is this, you walk without a sound, how many people have to be scared to death?

The staff of the memorial hall was stunned for a moment, and then came to their senses and hurriedly said, "I'm afraid of disturbing you, I'm sorry." ”

"It's fine. ”

"Oh leader, we have a phone in our office that you can use whenever you need it. The staff pointed to the BP machine on Yang Rui's waist and said.

Yang Rui suddenly said busily: "I'm not a leader, you don't have to be polite." ”

"It doesn't matter, it can be used even if you are not a leader, the people's phone is for the people. ”

"You're really good at talking, but I'm really not a leader. Yang Rui defended again, and said: "I came with my grandfather, and when the queue arrives, I will go out to call." ”

"It's okay, you can come to our office with grandpa to rest for a while, and we will arrange for you to pay homage to the statue in a while, and it won't be delayed." ”

The other party's attitude was cordial and sincere, which made it difficult for Yang Rui to refuse.

"Well, thank you. Yang Rui turned his head and asked for advice: "Then let's go over?"

"Okay. Yang Shan strode out of the queue.

Yang Rui followed behind the slender staff and enjoyed a privileged treatment.

I have to say that the privileged treatment is really convenient, not only did he call back in someone's office, and the phone bill was not paid a dime, but also, out of the office, he also plugged in the team, he not only plugged in the team, but also limited the time after the queue.

The crowd in line, even those who are about to arrive, do not seem to object to such an act of cutting in line. As a veteran revolutionary, Comrade Yang Shan has always been strict with himself, but he seems to have no problem with cutting in line.

After looking at the statue, Yang Shan was a little tired, and the staff who had been following Yang Rui immediately said: "Mr. Yang, why don't you go to our lounge and sit for a while, I'll make you a cup of tea, if the old man is sleepy, just squint for a while, we have blankets, and we won't catch a cold." ”

Yang Rui suddenly felt the meaning of hospitality.

"Well, thank you. Yang Rui helped his grandfather to the lounge of the memorial hall, only to see two more good-looking waiters appear, and sent tea, snacks, thin quilts and pillows at a flowing price.

"The quilts, quilt covers, pillows, pillows, and towels are all washed and steamed. The attendant smiled toothlessly, laid out the deck chair and left.

Yang Shan watched the door being gently closed, and couldn't help but sigh: "You said that the service in the capital is different, how intimate." It's not like a waiter in Nanhu City, the nose is not the nose at every turn, and the eyes are not eyes. ”

Yang Rui moved the corners of his mouth, and in the face of iron-clad facts, he had nothing to say.

Not long after, the BP machine rang again, Yang Rui called again, and simply made an appointment to the memorial hall.

Wen Zelin was not the only one who came, Ding Shiyi, Jiang Zhijun and Jiao Changchang all came.

When the staff of the memorial hall saw this scene, they felt more and more that they had made the right decision, and they were extremely attentive in serving tea and pouring water.

Jiang Zhijun looked around and sighed: "I can be regarded as well-informed, and it is the first time to meet people in the memorial hall." ”

Yang Rui was a little embarrassed: "I came with my grandfather, it just so happened, you drink some tea first, I'll find someone to take grandpa back, let's sit down and talk." ”

"Don't be so troublesome, I think so, let's go out and find a place to talk for a while, and let my orderlies stay here and watch." When the old man sleeps well and sleeps comfortably, let's drive back together and continue the conversation with you. Ding Shiyi deliberately lowered his voice as he spoke, and called his orderlies over again.

The orderly was a clever young man, wearing a military uniform and carrying Ding Shiyi's briefcase, which was reassuring to look at.

Yang Rui nodded in agreement, and then told the people in the memorial hall again, and then went out to take the car, and went to the front door to find a small door and sat down.

"We talked to Lao Jiao and thought that this business could be done and wanted to cooperate. Ding Shiyi didn't wait for the tea to brew, and then told the purpose.

Jiang Zhijun smiled dumbly: "Lao Ding, there is no such thing as you." ”

"Ding is Ding Mao is Mao, it's not interesting to pull calves. Yang Rui, please express your opinion. "Ding Shiyi's style is rough, but the effect is good.

Yang Rui was stared at by several people, thought about it, and asked first: "How many of you are going to go to the sea?"

"It depends on the situation, if you want someone to manage it, it is Xiaowen to go, otherwise, we will find someone to put on a name. Ding Shiyi didn't hide what he said at all, making several people roll their eyelids.

Yang Rui's mind is a picture of various collusion between officials and businessmen. (To be continued.) )