Chapter 770: Thalassemia
With the arrival of Tian Bing, the number of people in the ion channel laboratory expanded rapidly. Pen ~ fun ~ pavilion www.biquge.info
In a week, Yang Rui dug up three calves, namely Tian Bing and Jiao Yangping from Tsinghua University, and Wang Sisheng from Beili.
Among them, Jiao Yangping is the future cow who will become an academician, and he is very powerful, which can be said to be the pinnacle of Chinese scholars, and the number of Chinese academicians who have been in the past 30 years is still quite small, and there are even fewer biology majors.
Wang Sisheng of Beili has no experience of studying abroad or lecturing, but he can still reach the level of the Thousand Talents Program, which is also a relatively large calf.
As a result, Yang Rui quickly pulled up the research on genomes and cloning.
Not only Yang Rui, but also Xu Zhengping, Professor Cai, Dean Liu and others were also scratching their ears and cheeks excitedly.
They didn't expect to catch a bull who could become an academician or a Changjiang scholar in the future, but during this time period, domestic first-class scholars themselves are scarce.
It is only when a large number of scholars trained by US imperialism return to China that the number of first-class scholars in China can barely exceed the number of giant pandas in the same period.
In a single professional field, it is still the giant panda that wins.
As for the three people brought by Yang Rui, they are now the backbone of Tsinghua University and Beijing University, which is naturally equivalent to the backbone of Peking University, and they can be ranked firmly before 5% of the school's professor sequence in any school except Tsinghua University and Peking University, and they are the objects that all schools will woo. Even at Peking University, Tian Bing, Jiao Yangping and Wang Sisheng are also high-level scholars, and it is worth a lot of effort to win them over.
Of course, a calf is a calf after all, and it is still not to the extent of being wooed regardless of the cost, Yang Rui can pull it with his hands, which makes Professor Cai and Dean Liu very happy, but it is not necessary for them to pull it themselves.
What's more, there must be a certain opportunity to pull people.
It should be said that the publication of Genomics and the publicity of the Chicago Book have given scholars who have made it to the ion channel laboratory a good reason to do so.
In this era, transferring jobs because of money is a reason that can only be said in private, and in the open market, it is very immoral, and the academic circle of universities is destined to be a small circle, so even the reason of sufficient research funding will only be used by young scholars who are in a hurry.
After reaching Tian Bing's age and prestige, the reason why he can change jobs is either that he has collapsed with his old club, or that he can only go for lofty ideals and the pursuit of knowledge.
Nowadays, going to the author of "Genomics" can be regarded as the pursuit of knowledge.
Tian Bing is like this, Jiao Yangping is like this, and Wang Sisheng is like this.
The work of the ion channel laboratory has also become easier, counting the previous Su Xiankai and Fan Zhenlong, as well as Xu Zhengping, Yang Rui's researchers have six researchers, which is basically the same as the scale of the Huarui laboratory.
These are all real researchers trained after years of scientific research, Yang Rui guarded the laboratory for a few days and observed, and basically felt at ease.
Among the three newcomers, Tian Bing and Jiao Yangping are both thorough academics, and Yang Rui is familiar with the experimental techniques and the way of filling in the report, and Wang Sisheng's slight inferiority is nothing, so Xu Zhengping is familiar with the working methods of the ion channel laboratory after two days.
After a week, Yang Rui recruited two more dogs from among the applicants - the treatment was the same as that of Su Fan from Beiyan Agricultural College, and the recruitment work was over.
If you recruit any more people, the ion channel laboratory will not be able to be stuffed.
In fact, at this point, the workload of a laboratory is already quite large.
The trio even took a lot of work out of their former units - or benefits - as they called them.
At work on Monday, Yang Rui just arrived at the laboratory and saw a letter on the experimental table.
Wang Sisheng put down the test tube with a smile and walked over, and said with a smile: "Mr. Yang, the invitation I received before was a conference organized by Peking Union Medical College Hospital in conjunction with several universities and research institutes, national, there are exactly three places, I would like to invite you to go with Professor Xu Zhengping, do you think it is appropriate?"
Wang Sisheng is the youngest of the three new calves, about thirty-six or seventeen years old, and he still looks a little pink, and he doesn't know that he thinks he is still a recent graduate. Of course, at his age, he is placed abroad, that is, he has just graduated with a PhD.
Wang Sisheng took out good things to give gifts, and Yang Rui also intended to be enveloped, and immediately said: "Okay, one day, you call Xu Zhengping, let's go and have a look." ”
"The day after tomorrow is the pre-meeting, which is also the deadline for submitting articles, and then the meeting will be held in two days, and the place will be in Union Hospital, didn't they get a cooperation with the World Health Organization two years ago? Wang Sisheng said that the focus is naturally behind, he showed the invitation letter in his hand, and said with a smile: "The three of us take the formal invitation letter in, we can eat the buffet, and there are three vice associations, one can take a person in to listen to the lecture, but can not speak, nor can we eat the buffet, you see, who is better to elect the vice association?"
"You just need to discuss it with Lao Xu. Yang Ruicai didn't care about this kind of thing, but said curiously: "The guest house of Union Hospital, there is also a buffet now?"
"Isn't it fashionable? They definitely can't be open to the outside world like Sinovel Stadium, and they can't make money back. However, I do it from time to time internally, and everyone likes it. Wang Sisheng smiled and licked his lips, with some aftertaste.
Yang Rui smiled: "You seem to go often." ”
"How can it, you have to be invited to go, just this time in Beijing Concord, it is also an invitation coupon from a friend. ”
"So hot?"
"If you're going to go, you're going to do it, I'm almost there. Wang Sisheng shook his head with a smile and said, "Now people, just recognize the professor, and it is worthless to have a deputy in front." ”
"Write a few articles and you're a professor, don't worry. Yang Rui patted Wang Sisheng's shoulder to appease.
Wang Sisheng smiled helplessly. He did see the speed of the results of the ion channel laboratory, and finally made the choice, otherwise, it would be much more difficult to compete for professors at Peking University than at Beijing Institute of Technology.
Three days went by in a flash.
Yang Rui, Wang Sisheng and Xu Zhengping, plus Zhao Pingchuan and three other scientific research Wangs, got into two cars from Jielikang and went to the World Health Group Disease Classification Center of Union Hospital.
Zhao Pingchuan originally worked in the Tang Concentration Laboratory, and was assigned to Yang Rui's scientific research group for a long time. After Yang Rui's ion channel laboratory was established, he still often asked Zhao Pingchuan to come over, and after a long time, Zhao Pingchuan simply obtained Tang Zhong's consent and transferred to the ion channel laboratory.
Unlike the several head dogs recently recruited by Yang Rui, Zhao Pingchuan is just an ordinary Peking University student, without considerations such as establishment, he can change places if he wants to.
Moreover, compared with the conformity of Tang Zhong, a large number of projects in Yang Rui's ion channel laboratory can also make better use of Zhao Pingchuan's mathematical ability, since he arrived in the ion channel laboratory, Zhao Pingchuan has been the second author of the paper many times.
"The venue of Union Hospital has arrived. The driver of the car stopped the car steadily, got out of the car quickly, and helped Yang Rui and others open the car door as if welcoming foreign guests.
"Mr. Yang Rui!" The scholar guarding the door was dressed in a white lab coat, and he looked over because of the shiny run, but he let out a cry of surprise.
"Hello. Yang Rui looked at each other with a puzzled expression.
"I've seen your pictures and the news on TV. The white coat revealed the reason in a word, bent down to shake hands with Yang Rui, and said with a smile: "Director Yang can come to our concord, we are waiting for Peng Shenghui, Peng Shenghui, Director Yang, please here." ”
While introducing himself, the white coat took Yang Rui to walk 300 meters and send it straight to the conference hall.
Wang Sisheng's eyes were bright, and he sat down in his position before giving Yang Rui a thumbs up and saying, "Director Yang is famous and powerful. ”
"I've been reading martial arts books lately. Yang Rui smiled and made a fork. He is naturally famous, "Cell" and "Nature" are the world's top journals, and those who can publish articles on them are tied up by hospitals across the country, and there may not be a few. Although it is said that the main job of a doctor is not necessarily to post articles, it is still the most dazzling job to publish articles and produce results, however, Yang Rui is not here to show off, so he simply changed the direction of his speech to chat mode.
Except for a few people who came to say hello in the middle, in general, Yang Rui still chatted quite happily.
The good mood continued until the middle of the meeting, when the venue began to display a number of patient photos, Yang Rui's expression became solemn.
Enlarged photographs of patients from children and adolescents with deformed bodies, large abdomen, slender legs, and mutated heads.
"Globin dyspogenesis anemia is a genetic disease that has been found in China in recent years, especially in China's Liangguang region and central Sichuan, the treatment of intermediate and severe globin dyspogenesis anemia is very difficult, requiring long-term blood transfusion treatment, and the complications caused by long-term blood transfusion have further increased the mortality rate of patients......" The doctor who made the report on the scene then pointed to several pictures in front of him and said: " These are a few of the patients I have seen, ranging in age from 1 to 18 years old, and most of them are severe, with a swollen abdomen and a deformed head......"
"The rate of premature death of globin dyspoietic anemia is very high, because it is a genetic disease, severe patients often die before the age of 15 to 20, the average age in our country is even lower, the cost of expensive treatment is on the one hand, and the shortage of medicine is on the other hand......"
"The main reason for the early death of patients with globin dyspogenesis anemia is the side effect of iron accumulation, because the body can not produce enough hemoglobin and red blood cells, and patients often need blood transfusions, resulting in the enrichment of iron, which will have a serious impact on the function of various organs in the human body. At present, the most commonly used and the only iron chelator we can use is deferoxamine, which was first used in the clinic in 1963, causing a boom in the research of iron chelators in the medical field, but unfortunately, until today, there are still no new drugs ......"
"Nevertheless, we have the ability to tap into the potential of deferoxamine by studying the different clinical manifestations of DFO, or deferoxamine, for example, the microsyringe pump administration currently in use, which can improve drug distribution and accelerate iron metastasis metabolism...... Through the above methods, we have been able to increase the average life expectancy of patients by about two years......"
The doctor did not receive much applause at the end of his report, and although he was much more prepared than the others, the results were unsatisfactory.
Although clinically speaking, extending the average life expectancy of patients by two years is already a victory, but in the face of patients who die prematurely under the age of 20, such a victory is really a bit humble.
Yang Rui twisted his body uneasily and said, "Globin production disorder anemia is thalassemia." ”
"Yes, it's also called marine anemia. Wang Sisheng understood the relevant content and answered a sentence in understanding.
Yang Rui said: "In 82, that is, the year before last, when hider was researching hydroxypyridone compounds, didn't he discover a new iron chelator, deferione?
"Thalassemia is a hereditary disease, the main incidence of which is in Southeast Asia, as well as some black groups in Africa. Wang Sisheng shook his head lightly and said hopelessly: "The total number of patients with thalassemia is not large, and there are deferoxamine ......"
"Critically ill patients don't even live to be 20 years old, and of course there aren't many of them. Yang Rui pursed his lips, silent on the surface, but extremely uncomfortable in his heart.
……