Chapter 1165 - The Maniac Who Crosses the Membrane Seven Times
Liu Bingxian stiffened his neck and asked, "What's the matter, your street office can't control them anymore? Do you dare to coax them a little more?"
"You report, I'll come and see, I don't think the other party is a bad person, okay?" Xiao Chen gave a sentence casually, and then Liu Bingxian said: "If you want to break in again, that's your business, people sued the police, and it has nothing to do with me." Pen "Fun" Pavilion www.biquge.info"
"Just look at people and know if you're not a bad person?
Xiao Chen was dismissive of Liu Bingxian and said, "I can't see that people are bad people, you can see it?"
"I can see it. ”
"How can you tell?
"I just saw it anyway. Can a good person live in such a big yard? Either a landlord or a capitalist. ”
"Let me tell you, people are scholars from Peking University, don't mess with them. Xiao Chen shook his head, said more heavily, and said: "You have to respect the readers, when the time comes, people will call us to the street office, and our director will also have to hold it." ”
Liu Bingxian's eyes were about to bulge, and he argued strongly: "I see that the scholar is a white bone spirit, pretending to be the same, who knows what is inside." ”
"In Journey to the West, you are at most a servant, and if you meet a white bone spirit, you don't run quickly. Do you still want to go up and beat people?" Xiao Chen felt that what he said was good, so he secretly wrote it down, and prepared to go back and repeat it to others.
The 86 version of Journey to the West was screened during the Spring Festival, which was unprecedented, and the words in Journey to the West became hot words, and everything that talked about this belonged to a popular topic.
Liu Bingxian was stunned by what Xiao Chen said, stood at the mouth of the alley, and did not go home, and did not know where to go.
……
In the courtyard of the second entrance, Yang Rui and Su Xiankai slowly unfolded their previous discussion.
Su Xiankai is one of the future bulls in Yang Rui's memory, if according to the development of history, Su Xiankai's scientific research road was slightly bumpy, after all, with outstanding achievements in enzymology, he fought his way out and finally ascended to the position of academician of the Academy of Engineering.
Such an active calf should not be underestimated in his own strength, that is, the excellent conditions of the ion channel laboratory, the realistic large amount of money, and the prestige of Peking University finally attracted him.
Facts have proved that Su Xiankai's choice could not be more correct.
In just two years in the ion channel laboratory (joined in 84), Su Xiankai's line far exceeded the previous route, not only began to master a multi-million yuan scientific research group, but also studied G protein-coupled receptor related issues.
For a second-rate university graduate who has only graduated from school for a few years, Su Xiankai is an outlier in the eyes of others, not to mention that ordinary scientific researchers are not comparable, even within Tsinghua University and Peking University, ordinary professors do not have Su Xiankai's current qualifications.
What kind of qualifications?
The study of G protein-coupled receptors is a qualification.
Whether it's the 70s, '80s, '90s, '00s, '10s, '20s, or even the predictable '30s, if there is a biologist who is shy or proud to say: I have made some small contribution to G protein-coupled receptors......
Two conclusions can be drawn from that:
First, he's pretending.
Second, this product is awesome.
As of 2016, G protein-coupled receptors are the research direction that has won 10 Nobel Prizes.
What is the concept of 10 Nobel Prizes?
There are certainly more than 10 top labs in the world working on G protein-coupled receptors.
At the same time, it also means that any scholar who has made a breakthrough in G protein-coupled receptors will definitely win the Nobel Prize.
That's why it's so important, and that's why the biology community is heavily armed.
The so-called "battleground for soldiers" is also.
However, it is so difficult to crack that it has been called the most challenging field of biology.
At least half of the brightest brains in biology are concentrated in this field, and they do their best to seduce geniuses in chemistry, physics, mathematics, and even computers.
It is no exaggeration to say that in the direction of overcoming G protein-coupled receptors, the dogs who fill the trenches can go to third world countries to become academicians.
As for "Science", "Nature", and "Cell", as long as you dare to hang a G protein-coupled receptor in the name, it is not negotiable to publish it immediately.
What? What's wrong? Biologists all over the world teach you how to be a human being! If you find out too late, the global pharmaceutical companies will jump up and whip you.
You must know that after entering the 21st century, 50% of the world's new drugs target G protein-coupled receptors, and in layman's terms, half of the drugs are aimed at G protein-coupled receptors in the human body.
Such G protein-coupled receptors can be called the meat grinder of biology.
Even, there is nothing wrong with saying that it is a meat grinder of modern science.
There is no world-class scientific research level, no world-class scientific research experience, no world-class scientific research funding scholars, and there is no need to bother to make G protein-coupled receptors.
In other words, a tenured professor at Harvard may not be able to find a way to contribute to the problem of G protein-coupled receptors.
If it's animal husbandry or something, you can also take care of the cow in exchange for a little land, but the G protein-coupled receptor is a real man.
If "10 Nobel Prizes" is the honorary name of G protein-coupled receptors, "seven transmembrane maniacs (molecules)" is its attribute name.
Transmembrane refers to proteins that cross the cell membrane, usually templates, and transmembrane once is normal, and transmembrane twice is rare. It's like a normal man who "hey, hey, hey" once at night is normal, "hey, hey" twice is abnormal, and a man who "hey, hey, hey" seven times is only a legend.
The seven-time transmembrane maniac who won 10 Nobel Prizes is such a seven-time transmembrane maniac.
Bunker up!
Of course, in '86, the G protein-coupled receptor didn't win as many as 10 Nobel Prizes, but that also means that it still has a good chance of winning the Nobel Prize, or rather, making Nobel Prize-level results.
There are many factors that can win the Nobel Prize, but it is the first and most important to be able to make Nobel Prize-level achievements.
However, before Su Xiankai, Yang Rui did not really go deep into the G protein-coupled receptor, this thing is too difficult, so that it may not be possible to do it, and Yang Rui was not ready to challenge it before.
That is, a bull like Su Xiankai will plunge into it with a fierce son, and then ......
He didn't make it either.
I only heard Su Xiankai complain: "The G protein we finally purified, if we publish an article, it will be too wasteful." ”
"How many articles do you want to publish?" Yang Rui chuckled.
"It's not a matter of a few articles, I want to publish a good one. Su Xiankai glanced at Yang Rui and said, "The very good kind?"
"S isn't good enough?" Yang Rui understood a little, and couldn't help but tease more.
Su Xiankai smiled: "Of course it's good, it's ...... I don't think it's cost-effective to just publish the purified G protein. ”
Yang Rui nodded. Purification of G protein is a world-class research achievement, the world has now purified more than 20 kinds of G protein, and there are more than 80 types of G protein, so, unless the way to purify G protein has been exhausted, otherwise, the purification of a G protein is an S, no problem.
However, from a scientific point of view, the purification of G protein alone is still a high-level blue-collar job, just like a construction supplier that provides cement bricks is to a builder who uses cement bricks.
It is important to provide the cement bricks completely, but it is the person who builds the house that really matters.
Su Xiankai prepared the raw materials, but he didn't want to give them to others, but wanted to build a house by himself, which is easy to understand.
Yang Rui asked, "Where are you so far?"
Su Xiankai hesitated for a moment and said, "There is no progress. ”
Yang Rui smiled dumbly and sighed: "I didn't expect that there are experiments that you Su Xiankai can't do?"
"Director Yang, don't scold me. ”
"I'm not cold about you......" Yang Rui wanted to say, Academician Su Xiankai is a lot of bulls, and the Chinese academicians 30 years later are also ranked well in the world.
However, this is not easy to explain, so Yang Rui just smiled and said, "You can't do it, and you don't want to end it?"
"I want to keep doing it and give it another try. ”
"What to do?" There are many buildings available for construction with the building materials available.
Su Xiankai glanced at Yang Rui, hesitated slightly, and said, "I want to do the three-dimensional structure of G protein-coupled receptors." ”
As he spoke, Su Xiankai smiled, and the two canine teeth were extremely obvious, as if Teddy had been magnified.
This time it was Yang Rui's turn to be taken aback: "You know that there are tigers in the mountains, and you prefer to go to Tiger Mountain." ”
If the study of G protein-coupled receptors is a meat grinder-like siege battle, the study of the three-dimensional structure of G protein-coupled receptors is the attacking force in the siege army.
Yang Rui shouted "" in his heart, looked at Su Xiankai, and said secretly, it is really a cow, and the goals are different from others.
At the same time, Yang Rui also figured out that the question of asking for advice was false, and the request was true.
Yang Rui didn't say much, and asked first: "What do you want?"
"I'd like to ask you to lead the way. Su Xiankai replied seriously.
……