Yang Rui didn't find time to meet with Marjoli until noon. Pen | fun | pavilion www. ｂｉｑｕｇｅ。 ｉｎｆｏ

The laboratory behind him is doing a three-dimensional structure verification experiment, and once it is successful, it means that he has overcome the third stage of the G protein-coupled receptor, which is another Nobel Prize-level achievement.

Moreover, in 87 years, the difficulty of overcoming the three-dimensional structure of G protein-coupled receptors is also unbelievable.

By this time, Yang Rui had already felt that the Nobel Prize was beckoning to him.

Also excited is Gu Qiang. He knew that he would not be able to win the Nobel Prize, but the honor of being able to sign it again in an NCS-level journal was extremely full.

Su Xiankai, Fan Zhenlong and others couldn't help but congratulate Yang Rui.

Yang Rui is also beaming.

The whole laboratory was beaming.

Speaking of which, since the crystal structure of G protein-coupled receptors was made, the ion channel laboratory has invested a lot in the three-dimensional structure.

First, the Ion Channel Laboratory completed the second phase of the crystal structure study, which was the prerequisite for electron microscopy scanning.

Second, Yang Rui determined that electron microscopy scanning was feasible, and then desperately used electron microscopy scanning.

There are also a few laboratories around the world that do the three-dimensional structure of G protein-coupled receptors, but none of them can meet these two conditions.

Even the laboratories that have decided to use electron microscopes are far less invested than Yang Rui in this area.

In 87, the electron microscope was still very expensive, and Yang Rui had already purchased one when he was in the early days of the ion channel laboratory, and later bought a better one, which was naturally more expensive, and the cost of two copies would cost millions of dollars. After entering the third stage, Yang Rui rented a better and more expensive one, and equipped with two teams specializing in electron microscopes.

The cost of the instrument is more than 2 million, which usually means that the cost of a single use will be ridiculously high, in fact, in order to cope with such a clear electron microscope, the purity of the reagent and so on have higher requirements, and the investment of tens of thousands of yuan and thousands of dollars per day is also essential.

This is not a high price for the top international laboratory, but considering that this is only a branch of the project, it is a bit too high.

A normal laboratory would not spend so much money on a fork in the road until the direction is formalized.

There are too many forks in the road in scientific research, the same is to scan G protein-coupled receptors, is it like playing with DNA back then, doing crystallization and then X-ray, or using electron microscopy, or using nuclear magnetic resonance, or using some kind of chemical method?

There are so many routes to choose from, however, there is no such thing as a road leading to Rome, but it costs a lot of money to hit the wall.

After the introduction of the electron microscope, it encountered many problems.

To get the three-dimensional structure of a G protein-coupled receptor, like the three-dimensional structure of a building, an electron microscope scan not only to get the outline, the location of the various openings and elevators, but also to guess the interior, which was previously done by different people.

As far as the final result is concerned, the three-dimensional structure of G protein-coupled receptors can be written in at least one large and three small, a total of four papers.

The four papers are naturally eligible for S, but the depth and breadth are different, and the future expectations are different.

What Yang Rui handed over to Marjoli was the first big paper, which explained the three-dimensional structure of G protein-coupled receptors as a whole, and the remaining three articles were separate items.

In terms of normal laboratory progress, it takes three or four years to do a similar big project, but if it is done in two years and you get four S-level papers, it is a big profit. If it is made in four years, it will not be a loss, and longer projects are actually more common, but counting the marginal effect, it is tolerable to produce 4 papers in 6 years.

As for publishing 4 papers in a few months, and a super luxurious big paper, this belongs to the role of Yang Rui's golden finger aura, but it is incomparable to others.

"Mr. Yang Rui is in a very good mood. Ma Qiaoli put down the tea that had been bland, looked at Yang Rui coming, and quickly stood up, which was very different from his previous attitude.

Yang Rui nodded and said, "The recent experiments have gone well. ”

"Congratulations. ”

"Thank you. ”

Mr. Yang Rui...... Alas, that's a difficult title, I heard you're still studying?" said Marjoelli. Swedes don't greet each other, but when necessary, Swedes can learn from foreigners.

Yang Rui nodded and said, "I haven't gotten a bachelor's degree yet, and I'm only a senior after the summer vacation." ”

The corners of Marjoli's mouth twitched twice, and he said: "I have met a lot of scientists, but none of them who can reach your current scientific research level are under the age of 30. ”

"This is a bonus for developing countries. Yang Rui said lightly: "China's scientific research and economy are developing, and there are not so many rules and regulations......

Marjoli listened and nodded, but he didn't care what Yang Rui said.

He observed Yang Rui's expression, and when Yang Rui spoke, Fang said: "Mr. Yang Rui, my colleagues and I have just read your paper carefully, and I have to say that it is very exciting. ”

Yang Rui glanced at Marjoli's dark circles, knew that he hadn't slept all night, and said with a smile: "If I can get praise from Swedish scientists, I can also submit the manuscript with confidence." ”

"If you don't mind, can I recommend a journal for you?" Majoli seized the opportunity and hurriedly spoke.

Yang Rui raised his eyebrows and asked, "Which one do you want to recommend?"

"I have a good relationship with Gavin Jeremy from Nature, and if you're willing to submit to Nature, I can help. "Marjoli was very attentive in his presentations, which scientists rarely do.

The editor of an academic journal has some power over whether or not to publish a paper, but the larger the journal, the less power the editor has to decide. Journals such as Nature and Science can be said to be of interest to scholars all over the world, and the scope of peer review is also very wide, and the recommendations of the editors themselves are not necessarily valid, and the recommendations of outsiders are even weaker.

On the other hand, scholars like Yang Rui have published articles in Nature before, and naturally have familiar editors, so they can submit their manuscripts, and there is no need to pull relationships at all.

Yang Rui looked at Marcholi suspiciously and said, "I haven't decided which journal to submit my paper to. ”

"Of course, of course. Marjoelli smiled and said, "But I don't recommend Jeremy because he works at Nature, but more importantly, he's Swede, like me." ”

"Oh. ”

"Dr. Jeremy has been able to exert considerable influence in the affairs of the Nobel Prize. Marjoelli finally pierced the window paper and said, "I have worked with Dr. Jeremy for many years, and our joint recommendation can help you get on the bigger stage." Mr. Yang Rui, it would be our honor if we could recommend your paper. ”

What he said was neither humble nor arrogant, and he was also a craft.

And in his heart, Marjoelli also has a touch of arrogance.

But any scholar who is interested in the Nobel Prize knows very well how rare it is to exert influence in Nobel Prize affairs.

Marjoli believes that even if Yang Rui doesn't kneel and lick it immediately, he will show the appearance of being a gentleman.

Of course, Marjoli would have comforted the young man in front of him - he had been preparing for this moment for thirty years.

"Dr. Marjoli. Yang Rui's tone was a little more sincere, and said: "Thank you very much for your favor, but in terms of publicity, I already have supporters in Sweden." ”

Yang Rui didn't mention the word Nobel Prize, and he didn't need to mention it.

Marjoelli was stunned and asked, "Who?"

Yang Rui smiled, did not answer, and said, "I hope we can have the opportunity to cooperate in the future." ”

Then Marjoli opened the door of the reception room, smiled at the Swedish scientists, and went deep into the crowd.

Marjoelli stayed alone on the sofa, wondering in his heart: Who snatched my Yang Rui? Who dared to snatch my Yang Rui?