"Uncle, please ask, Director Yang is here. Combing through the translation of three or seven points, he came to the door of the ion channel laboratory, and with a smiling face, handed a cigarette to Uncle Qin, the porter.

Uncle Qin took it unceremoniously, looked at it, and found that it was all in English, so he put it in his mouth, and said vaguely: "The conditions are good, and I can afford to smoke outside the cigarette." ”

The translator hurriedly lit a cigarette for him and said with a smile: "To do things for foreign companies, you have to decorate the façade." ”

"Well, the taste is strong enough, a little bit of smoke pot. Uncle Qin commented.

The corner of the translator's mouth twitched twice, and he said in his heart: If you want to smoke the pot, I will weigh you a pound of loose cigarettes.

Uncle Qin inhaled a third of it in one go, spit it out, nodded comfortably, and then said, "Which unit are you from? What is the matter with Director Yang? Have you made an appointment?"

While asking, Uncle Qin unfolded the registration book, pushed it in front of the translator, and said: "Foreigners also need to see documents, we are a confidential unit here, you know." ”

"Yes, yes. The translator's eyes glanced at the police booth next to him, and the armed police soldiers who came at some point, and asked with a little cloudy head: "When will there be armed police standing guard in our ion channel laboratory?"

"To make a new medicine, it's all as much money as the sea, can you do it without sending armed police?" Uncle Qin took it for granted.

In terms of the value of new drugs, the cost and profit of tens of millions of yuan at every turn are indeed more than most state-owned enterprises in China.

Fortunately, the foreigner didn't understand, and the translator filled out the registration book, so he turned back to the customer and smiled: "Mr. Leander, the Peking University Ion Channel Laboratory is a government-invested laboratory, and they only send the police to ensure its safety, and they do not restrict the entry and exit of foreigners, and it will not affect your stay in China." ”

"Are you sure?" Leander was a yellow-haired foreigner with some gray hair, his eyebrows sticking out of his forehead an inch long, and he was very carefully trimmed.

"I'm sure. The translator gritted his teeth and gave an answer, afraid that the foreigner would regret it, and said busily: "Director Yang is in the laboratory now, I just registered, but we are ranked sixth today, we may not be able to see it, I have to call to confirm it in a while, why don't I take you to play for an afternoon and come back tomorrow?"

"Mr. Yang Rui must be very busy now, you can confirm with them again, I really want to cooperate, maybe we can meet in advance. Leander spoke as slowly as he could, so that the interpreter could understand what he was saying.

The translator was stunned for a moment and said with a smile: "Okay, then I'll discuss it again, but people said that there is no time today, and Director Yang will not accept guests today." ”

Leander nodded silently.

The translation is a little weird, but there is an inexplicable pride in my heart. In the past, although it was easy to pit foreigners' money, after all, they were called to drink, arrange some travel or something, and also have to endure foreigners' unreasonable interpretation of Chinese culture and history, but now although it is a little begging for help, it is a foreigner begging Chinese, he is just a middleman, but he feels excited.

After asking two more specific sentences, he translated them to the front of the gatehouse, muttered for a long time, turned around, and asked Leander: "Would you like to meet Yang Rui with others?"

"See you together?"

"I said that you are the manager of a pharmaceutical company, and the other party said that if you are willing to join the managers of other pharmaceutical companies, you can advance, otherwise, you will have to wait. ”

Leander glanced at the porter Uncle Qin suspiciously, and asked, "Does he have the right to make this decision?"

"Maybe it's been decided a long time ago in the ion channel lab. ”

"Okay, if we meet together, can we meet Yang Rui today?"

The translator shook his head slightly and said, "It can only be tomorrow afternoon." Or, I'll take you to the Forbidden City, which is full of Chinese antiques and artifacts. ”

"What will Mr. Yang Rui like? Let's go buy something he likes. Leander said purposefully.

The translator opened his mouth, nodded his head, and said, "Then let's go to the Friendship Store." ”

The next afternoon.

Leander had a light lunch and took the canned food and malt cream from the Friendship Store to the ion channel lab.

From personal experience, Leander did not believe that Yang Rui would like canned food and malt cream, but the translator said that this was a high-end gift given by Chinese to each other, and Leander believed it. After all, what country doesn't have a hobby?

Yang Rui was a little confused when he received the gift from Leander in the living room, to say that these days, there are also foreigners who try to bribe, but it is not appropriate to buy it from canned food and malt cream?

"Mr. Leander, please wait a moment. Yang Rui could only put the canned food and malt milk essence on the table, and told the scientific research dog who helped in the conference room to bring it back to the foreigner later.

Leander was very happy, felt that Yang Rui accepted his gift, and let go of his courage and asked, "Professor Yang, may I ask which other pharmaceutical companies will participate in the talks?"

"Greenstone Point, GlaSmithKline, and Jielikang are sure to participate, and I'm not sure if the other ones will come. Yang Rui casually said a few names.

Leander, however, immediately sensed the threat of an approaching enemy.

Compared to his company Kaliz Pharmaceutical, Jie Li Zeneca and GramSmithKline can be said to be behemoths.

Leander didn't have a chance to speak, but just raised his hand to look at his watch, and several men with blonde hair or brown hair or white hair walked in.

Yang Rui looked a little funny, Europeans and Americans haven't started to play diversity yet, so on both sides of today's conference table, there are all white men sitting, not to mention that there are no colored people, not even a woman.

The pharmaceutical companies of the 80s were pure patriarchal politics, and if they weren't for that, they wouldn't have organized women's PR projects.

Yang Rui thought so crankily, and when the others sat down, he said, "Everyone's time is precious, so I'll get straight to the point." ”

He uses Chinese, and he has his own translator next to him to worry about how to translate straight to the point.

After the latter said in English, Yang Rui said: "Everyone who came to the ion channel laboratory today is interested in the drugs that are being used in this laboratory. Considering the professionalism of medicines, I have prepared some brochures for you to see. Well, after reading it, please return the booklet. ”

After saying that, someone began to distribute paper products printed in black and white.

"Gaucher disease?" Leander saw when he opened the pamphlet.

"Yes, grape encephaloglycosis. According to the classification of Europe and the United States, this is a rare disease, and the current number of patients, in the world, is not very large, roughly around hundreds of thousands. Yang Rui paused for a moment and said, "Therefore, in order to balance expenses, the partner I need should be a company that has the ability to apply for rare diseases, preferably a company with rare disease sales experience......

Yang Rui said hundreds of words freely before letting the translator speak.

Representatives of several companies did not pay much attention to this aspect.

Big Pharma companies have a lot of hands and eyes, even if it's transnational politics, let alone the compliance application in their hometown.

What they really focus on is still whether Yang Rui will be able to make a new drug.

"What kind of approach do you want to use for drug development for Gaucher disease, and how is it progressing now?" said GlensmithKline's manager, who wore glasses and dragged it slightly, with a somewhat shrewd look.

"Enzyme substitution. Yang Rui replied without hesitation.

Gaucher disease is a disease caused by a genetic mutation that, in the final analysis, is a lack of grape cerebrosidase. Because the structure of the patient's glucocerebrosidase changes and cannot perform its due functions, the human body produces a series of symptoms, such as splenomegaly, anemia, bone lesions and nervous system disorders.

Theoretically, supplementation with adequate amounts of glucosidase can improve the symptoms of patients with this disease.

However, this is obviously not an easy task, and RB enzymes have no effect at all at such times.

GlensmithKline's manager also looked at Yang Rui with suspicion and asked, "Can the enzyme substitution method, which is said to be extremely costly, be used for pharmaceutical-grade production?"

"It's good to keep costs down, and I'm still very confident in that. ”

Yang Rui's expression was also full of confidence.

The development of new drugs is no stranger to Yang Rui.

To put it mildly, there are no more than 200 scientific research units around the world that can have Yang Rui's level of proficiency.

The reason for this affirmation is that there are not yet 200 new and real drugs developed by people who are still alive in the world.

Don't look at the 90s, the entire Western world, or the world, developed more than 4,000 kinds of new drugs, but the real new drugs, that is, new drugs made of a completely new compound, rather than the isomer of the old compound, the total number is more than 100.

Deferiprone is one of them.

Although Yang Rui did not operate the whole process to the listing of deferiprone on the market, there is not much that developers can do after the second phase of clinical trials, unless they want to cheat, otherwise, the new drugs from the third phase are basically outsourced to specialized companies to do clinical trials. Tens of thousands of clinical patients are needed, not drug developers – at this point, developers can't change the composition of the actives, and can only resign themselves to fate.

Deferiprone has gone through the choice of fate and is already facing the market - the development of a new drug has been completed so easily, and there have not been many repetitions, such a result, to be honest, has shocked the attention of some analysts.

Now, with the addition of the Nobel Prize, Yang Rui's success is somewhat taken for granted, and the news that the ion channel laboratory of Peking University is trial-producing new drugs will attract so many pharmaceutical companies at once.

However, it is one thing for pharmaceutical companies to be interested, and it is another thing for investment or cooperation, Leander glanced at GramSmithKline's manager again, hoping that he could ask Yang Rui further in order to get more information and make a judgment.

GramSmithKline's manager, sure enough, pondered for a few seconds, raised his head again, and said, "We, GramSmithKline, are willing to invest $1 million to obtain a 10% interest in the future of the drug, is this okay?"

Leander's jaw almost dropped, so give the money? Are you so rich?

Leander hurriedly looked at the others, only to see the manager of Greenstone Corner, Shi Shiran said: "$1.5 million, 10% interest!"

Just one round of bidding raised the price of Yang Rui's new drug by $5 million.

Leander was dumbfounded, aren't you afraid of being pitted by Yang Rui?

(End of chapter)