"Genomics illuminates the way forward for the brave, it is changing the ecology of the field of genetics, and cowards may be afraid of genomics today, just as they were afraid of genomics back then, but, ladies and gentlemen, genomics has taken a step, and we can either follow it or we can only look at it from afar......" Linden's exposition is simple and vivid, very flavorful of American movies in the seventies. Pen fun and pavilion www.biquge.info

To the ears of Chinese, this way of speaking has both a sense of familiarity and an American flavor, and they can't help but applaud.

Applause for friends from the United States, everyone is working hard.

Director Ma also applauded vigorously, especially after Yang Rui came to power.

"Thank you, Mr. Linden. Yang Rui took the microphone, smiled, and said: "Thank you Norton Press for the invitation, so that we can gather together today, because it is a gathering organized by a publishing house from the United States, we will not invite the leaders to speak in accordance with the rules of the United States for the time being......

There was a burst of laughter from below, and for the current countrymen, especially civil servants and officials, such jokes are very deep.

Yang Rui smiled again, grabbed the "Genomics" on the small podium, showed it to everyone, and said: "I want to talk about genomics, more precisely, it is to talk about the development of genomics, as we all know, the research focus of modern genetics and biology is related to structure, that is to say, the focus we currently hope and need to know is the structure, the structure of genes, the structure of proteins, the structure of cells, this is the article we see the most in "Nature" and "Cell", it is the current hot spot, but ......"

"Forward-looking, structure should not be our focus, of course, we still need to study structure, but the study of structure, should not be the focus, nor should it be a hot ......"

"What is the focus and hot spot, I think, should be the function!"

"Functional genomes, functional proteins and functional cells are our goals, priorities and hot spots, which is also the main reason why I wrote Genomics......" Yang Rui's topic was very high, and his eyes were deep.

He had reason to prove with a deep look in his eyes, because the speech he was making was indeed important.

Yang Rui is predicting the arrival of the post-genomic era. The genome here was originally the Human Genome Project, which means biology after the Human Genome Project.

However, if the post-genome era of the Human Genome Project is replaced with the post-genome era after "Genomics", it does not seem to be too much of a problem.

The crux of the matter lies only in the fact that the functional genome replaces the structural genome.

Genomics was originally a theoretical guide to the Human Genome Project.

In short, Genomics is the equivalent of architectural design, and the Human Genome Project is the actual engineering construction.

Yang Rui naturally wanted to take this opportunity to brush his face more.

The prophecy of not wanting money may not mean much to ordinary people, but it is of great value in the scientific community.

Yang Rui has done such a thing before, and it is also very profitable.

So, he couldn't help but prepare to do it again.

Just as astronomers predict black holes, biologists can make a name for themselves if they succeed in predicting the post-genomic era.

Yang Rui hopes that his "Genomics" can soar through the prediction of the post-genome, and when the time comes, when people talk about the post-genome era, they will naturally mention Yang Rui's "Genomics".

It is even possible to call Genomics a theoretical guide for the entire post-genomic era.

The so-called big bull that can't get around is like this step by step, like a technical barrier, you have to stack one brick on top of another, and smear cement in the middle, so that it will be more stable.

Just like Newton, if you only make a Newton Leibniz equation, although this brick is very strong, very tight, and enough for Newton and Leibniz to be called the darlings of the times, but after all, it is not Newton, but if you add the algebraic brick of integralization, it will be different, this is an important step in shifting mathematics from the discipline of feeling to the discipline of thinking, and it is the founder of real natural science.

Of course, if this is all there is, Newton is still not Newton, that is, with analytic geometry and polar coordinates, plus "Cubic Curve" and "Generalized Arithmetic", he is not the Newton in people's impressions, but can only be said to be a great mathematician, on a par with the little prince Gauss and the great emperor Euler.

And the reason why Newton is Newton is that in the big wall he built, there are Newtonian mechanics composed of Newton's three laws, as well as the law of gravitation, the law of planets, and the law of optics...... So, in the end, it was Albert Einstein who went hand in hand with him......

"Genomics" is Yang Rui's first book, and it is a very representative brick, so Yang Rui spent a lot of thought and extended the speech to a rare 15 minutes.

Of course, this is nothing in terms of domestic speeches.

It was a little pity that no more than a quarter of the people present could understand what he was saying.

But Yang Rui didn't care, this speech was not just for the audience, just as the speech at the secretary's office meeting was not just for chatting with other people in the conference, or the report at an academic report was not just for the scholars present.

The post-genomic era will not be realized today or tomorrow, but one day in the future, when the era of functional genome research gradually replacing structural genomes really comes, today's speech will become very meaningful.

Just as patents are not meant to be validated at the time, patent barriers are not designed to deter today's patent thieves.

However, the scholars who could understand it, mainly those from the universities and research institutes that were invited, listened quite carefully.

The concept of the post-genomic era is actually very simple, in layman's terms, it is to replace structure with function.

The so-called functional genome is to investigate the function of a genome, such as the existence of the leg shake gene, its function is leg shake, if the shake m gene exists, its function is to shake m, as for its structure, although it still has great significance for biology, but from a more macro perspective, the significance is not as great as the function.

In the final analysis, as Yang Rui said, this is the question of who is more important. It's not that structure isn't important, it's that function is more important.

In the past few years, people did not have the conditions to do functional genomes, so everyone was more interested in doing structural genomes, but with genomics and the Human Genome Project, structural genomes should give way to functional genomes.

A quarter of an hour later, Yang Rui's speech ended, and someone immediately raised his hand below.

"This ...... We're not holding an academic presentation. Lyndon of Norton stood up and smiled, "We didn't have a defense. ”

"Just one question. The man who raised his hand was an academic man in his 30s with glasses.

Lyndon hesitated for a moment and said, "Just one question, may I ask." ”

"I would like to say that we need to understand the structure before we can understand the function, and there is also the advantage of studying the structure first, we can know the unknown function of an unfamiliar structure through the same or similar structure......"

"I prefer to call what you're talking about as comparative functional genomics. Yang Rui shrugged and said, " On the basis of genome mapping and sequence determination, comparing known genes and genome structures to understand the function and expression mechanism of genes will be the focus of development in the next few years, but I would like to say that the ultimate direction, our ultimate goal, is to use the information provided by structural genomics, the development and application of experimental methods, at the system level, to study the function of the genome, so as to expand the research object from a single gene and protein research to the joint action of multiple genes and proteins......"

The academic man with glasses tilted his head and said, "Your end is too far away, how many years, 50 years, 100 years will it take?"

"How about 15 years. Yang Rui said: "In 25 years at most, we will fully enter the era of functional genomes." ”

"How could it be. The glasses academic man smiled: "We have to do structural genomics first, all genes and proteins, how many years will it take? Even if it is only 50%, or 30%, 50 years ......is not enough."

"It is not necessary to complete the structure of all genes and proteins, 30% is not necessary, in fact, the human genome project should be launched immediately, fifteen years, enough time for us to understand the structure of genes. Yang Rui smiled, put down the microphone, and gestured to Lin Deng.

Lyndon immediately walked up to the stage, ended the conversation, and said with a smile: "Now please welcome our guests......"

This is where the boring leader's speech begins, and the glasses academic man can't ask if he wants to.

Director Ma waited for Yang Rui to sit on the chair and said with a smile: "The one who asked just now doesn't seem to be convinced. ”

Yang Rui glanced back, and the glasses academic man really had a stomach, but he hadn't said enough, if it wasn't for the seriousness of the scene, he might have run over now, or simply stood up and shouted.

"I can't help it if I'm not convinced. Yang Rui smiled and said, "It's not for him." ”

"How?"

"It's a prophecy, a prophecy like that, discussed before it comes true, always arguing, I don't think it's necessary. Yang Rui said simply.

"It's disdainful to explain. Director Ma saw through it at a glance, he was too familiar with Yang Rui's expression.

Yang Rui didn't explain, but still smiled lightly.

"Speaking of which, Xiao Yang, I'll call it that, what do you do at home. "Director Ma looks like a good elder.

"Oh, my father used to be the secretary of the township party committee, and now he has been transferred to China Merchants. "Yang Rui has nothing to hide, this is all public information.

Director Ma nodded "oh" and said with a smile: "China Merchants Bureau? and the Commercial Bureau have a system, I'm quite familiar with this piece." ”

"You're not from the Ministry of Education?"

"You know what to sign between ministries and commissions, and I often go to the Ministry of Commerce to sign it. "Inter-departmental cooperation often requires the signature of leaders of different departments, which is called countersigning, and running to sign is to urge signing. The power and responsibility of the directors of the central ministries and commissions are also related to this.

Yang Rui said casually: "Do the Ministry of Education and the Ministry of Commerce still have to communicate often?"

"Nowadays, who doesn't want to deal with the Ministry of Commerce. Director Ma laughed and said, "Fortunately, I am in the Ministry of Education, if it is the Education Bureau, I am really embarrassed to run the Ministry of Commerce." ”

Speaking of this, Director Ma paused and said: "After all, I do have a few friends in the Ministry of Commerce, who are also senior intellectuals, maybe you have something to talk about, I will make an appointment one day to talk together." ”

"Okay. Yang Rui said casually.

Director Ma didn't see it this time, he only felt that he was almost laid the ground, and gestured to the back with his eyes.

The man who had bitten his ear with Director Ma immediately stood up and said with a smile: "Yang Rui, you are lucky, Director Ma likes to promote young people the most." ”

"Thank you, Director Ma. "What can Yang Rui say, I can't say, I don't need your promotion.

The man sitting on the right side of Director Ma, he came over to the ****, smiled charmingly with a scruffy beard, and said: "Yang Rui, at this time, you can't be shy, do you know what Director Ma is in charge of in the ministry?"

"What's the matter?"

"Let's not talk about anything else, the university's textbook review is under the management of Director Ma. The scruffy and charming man held his chin with his hand and winked at Yang Rui.

Yang Rui was stunned, he really didn't expect that the person next to him could really promote him, and he could only say that the responsibilities of the Chinese government are so comprehensive.

"If your book can be included in the university's designated textbook, that is, the catalog of reference books, you can sell a lot more. The charming man continued to add weight.

Yang Rui nodded. Not only can it sell a lot more, there are so many colleges and universities in China, if it can be included in the textbooks, the purchase of the library alone can completely explode the sales in the United States, each student has a copy, and no matter how cheap the price is, the publisher and the author can make a lot of money, and it is no wonder that Director Ma will be invited by Norton Press to participate in today's publication briefing and sit next to him.

"Director Ma, please advise. The county official is not as good as the current management, and Yang Rui also cooperated and gave a smile, so as not to be arrogant to him.

"Okay, well, I like to teach young people the most, and when I have time, let's have a good chat. Director Ma said and handed Yang Rui a business card, asking Yang Rui to find himself, which was naturally more imposing than him looking for Yang Rui.

……