Chapter 99: Leukemia
Yuan Man handed the test report to Dr. Hou, who read it carefully and whispered, "I really have leukemia." ”
Yuan Man suddenly felt that the sky was falling, and he suddenly stood unsteadily, and fell to the ground with a bang, which scared Zhao Wei a lot.
"Husband, husband, are you okay?" Zhao Wei helped Yuan Man up and asked with concern.
Yuan Man's face was pale, his eyes were blank, and his lips were closed and speechless.
"Husband, don't scare me!" Zhao Wei shouted.
Qin Guizhi and Zhou Wei also shouted loudly for Yuan Man.
After a long while, Yuan Man came back to his senses, and tears immediately flowed.
"What should I do?" Yuan Man cried with tears in his eyes, "How could Zhouzhou get leukemia?!"
"Doctor, is it a misdiagnosis?" Qin Guizhi asked without hesitation.
Although Qin Guizhi is a doctor, he also knows that the doctor is very disgusted with the word "misdiagnosis", but he still said it in a hurry. Because at this time, she is no longer a medical worker, just Zhouzhou's grandmother. Her first instinct was to deny the result.
Fortunately, Dr. Hou understood their feelings, and did not care about the word "misdiagnosis", which was insulting to the ability of doctors.
"According to various tests, the patient did have leukemia. Dr. Hou said calmly. The characteristics of the doctor's profession make him talk about his condition very calmly and without personal feelings.
"How can my grandson have such a good body, how can he get leukemia?" Qin Guizhi cried.
Zhou Wei didn't speak, he didn't cry, he just pursed his mouth tightly, and the corners of his mouth trembled slightly. It can be seen that he is trying his best to suppress his sadness in the bottom of his heart.
Zhao Wei hugged Yuan Man's head tightly in her arms and sobbed in a low voice.
Dr. Hou waited until everyone was almost crying, and then said calmly, "Don't cry yet, let's discuss the condition and treatment plan first." ”
Everyone sobbed for a while, slowly calmed down, and listened to Dr. Hou's introduction to the condition.
"Leukemia is a malignant clonal disease of hematopoietic stem cells. "To put it simply, hematopoietic stem cells do not make the fresh blood that our body needs, but instead create some blood that harms our body." Just like cancer cells, they are cells, but they are malignant cells that kill us. ”
"Leukemia is also called blood cancer. Qin Guizhi added, and cried in a low voice, "Cancer! Why is my grandson so miserable?!"
Dr. Hou reassured the crowd, "Although leukemia is called blood cancer, it is not incurable. ”
"Is this also a cure?" Qin Guizhi asked with tears in his eyes.
"There are now more mature ways to treat leukemia. "First of all, we need to do combination therapy, which is induction therapy. If remission is achieved after induction therapy, intensive consolidation chemotherapy can be given or stem cell transplantation can be initiated. ”
"What is the effect, what is the effect?" asked Yuan Man.
"The era of the 'incurable' disease of leukemia is over. "Now leukemia has greatly improved the prognosis of leukemia through chemotherapy, radiotherapy, targeted therapy, immunotherapy, stem cell transplantation and other treatments, and a considerable number of patients can be cured or stable for a long time." ”
"But how did my son get leukemia?" Yuan Man was puzzled.
"Leukemia is usually caused by viral infections, chemicals, radiation, and genetics. Dr. Hou said.
"Heredity?" Yuan Man asked, "Did I inherit it to him?" Yuan Man blamed himself for this.
"Familial inheritance. "Actually, it's not that strict when it comes to saying it's 'genetic'. The correct expression is 'genetic predisposition'. That is, people with a family history of leukemia have a higher chance of developing certain types of leukemia than normal people, and people with a family history of leukemia have a higher chance of developing leukemia than normal people with the same triggers. ”
I listened to Dr. Hou talk a lot, to put it bluntly, isn't this still hereditary. As with all cancers, although it is not said that there is genetic, there are cancer patients in the family who are also susceptible. Yuan Man was afraid that he would inherit his father's cancer, so he went to check for hepatitis B.
After everyone's pain, even if they have no choice but to accept this cruel truth. Then there's the cost of treatment.
"The treatment of leukemia is indeed a relatively large cost, and it is a heavy burden for a family. Dr. Hou said, "The treatment of leukemia first requires chemotherapy, and some types of leukemia can be cured by chemotherapy alone, about 100,000 yuan." But if you want to transplant bone marrow, the cost is between 200,000 and 500,000. ”
Such a huge medical expense made everyone take a breath of fresh air.
"The cost of 500,000 yuan is mainly bone marrow matching. Dr. Hou said, "If you look for a match from the China Bone Marrow Bank, it usually costs 300,000 to 500,000 yuan. If bone marrow matching is carried out between siblings, then 200,000 is enough. That's what people often say, treat 200,000 leukemias. However, you have to consider the cost of chemotherapy, and if you have a cold or infection, you have to spend another 30,000 or 40,000 yuan. But you don't have to worry about this, because now childhood leukemia can be reimbursed, and treatment in designated medical units can be reimbursed 70%. Of course, according to the type of leukemia, medication and type of surgery, there is a very specific reimbursement plan, which I don't know very well, you can go to the medical insurance to ask. In short, looking at leukemia now, money is secondary, and the most important thing is bone marrow matching. ”
"Then when will the bone marrow be matched?" asked Yuan Man.
"Of course, the sooner the better. "If the cost is ready, we will start preparing the bone marrow matching right away." ”
"What are the ways of bone marrow matching?" Yuan Man asked, "because I heard you say just now that bone marrow matching is different, and the cost is different." ”
"According to the different sources of stem cells, they can be divided into three types: autologous, homogeneic and allogeneic. Dr. Hou said, "Autologous bone marrow transplantation is the transplantation of bone marrow from the patient's body. However, the patient himself has leukemia, so this transplant, although the lowest cost, is the most unavoidable option. The best bone marrow transplant is a syngeneic bone marrow transplant. Homogeneic bone marrow transplantation refers to the transplantation between identical twin siblings, because the donor and recipient are genetically identical, so there is no immune incompatibility problem like autologous bone marrow transplantation. Allogeneic bone marrow transplants are more likely to be rejected. Therefore, if there are no identical twins to provide bone marrow matching, then allogeneic bone marrow matching should be done early. It really can't be done, so the bone marrow can only be extracted from the patient himself. ”
"If there are no identical twins to provide bone marrow matching, and autologous bone marrow is not good, then can only count on the bone marrow outside?" Zhao Wei asked.
"Yes. "Due to the large number of patients who need bone marrow transplantation, bone marrow matching has always been in short supply, and patients are waiting in line, and some patients can't even wait for the match...... Alas. ”
"Can your parents be matched?" asked Zhao Wei.
"My parents can also match their children with bone marrow, but it is not a 100% match, and there is only a 50% chance of success. Dr. Hou said.
"Hey, the children are all born to their parents, why can't it be considered an genetic bone marrow transplant?" Zhao Wei felt very strange.
"A child receives half of his genes from his father and half from his mother, so he is 50% compatible with his father or mother, commonly known as hagistically identical. Syngeneic bone marrow transplantation refers to the bone marrow transplant of identical twins, and the match is 100% compatible, and the probability of being with siblings is 25%. The probability of compatibility between cousins and cousins is very low, and it is already an allogeneic match, and the probability of compatibility is between 1 in 30,000 and 1 in 1 million. "It's a very helpless reality. ”
"Wouldn't it be a hassle if you didn't have identical twins. Zhao Wei said.
"Regardless of whether they are identical twins or not, bone marrow pairing is required, and the gene pair site must be identified before transplantation is possible. Once the gene alignment site is identified, rejection tests are performed until it is safe to do so. The success rate of bone marrow transplantation between relatives can reach 75%~95%. Dr. Hou said.
"Hurry up. Zhao Wei hurriedly said, "Hurry up and find the bone marrow that can be matched." ”
"If you guys decide and the costs are ready, we can get started. Dr. Hou said, "Sooner rather than later, there are many patients waiting for matching." ”
What's the matter? There's only a doctor! Hurry up and prepare money!
But Qin Guizhi meant to try it in big places like Beijing and Shanghai, saying that the level of hospitals in these places was higher.
"After all, we are a third-tier city, so how can the medical level compare with places like Beijing and Shanghai?" Qin Guizhi said, "Those places are national first-tier cities, where all kinds of high-quality resources are concentrated." ”
"But, Mom, what about reimbursement when you go to places like Beijing and Shanghai for treatment?" Yuan Man asked.
"Actually, Beijing and Shanghai are the big places, but the technology for treating leukemia, I think it's similar, they are famous. "There are also many private hospitals that don't reimburse medical expenses. ”
"Hey, why do you say that?" Qin Guizhi said dissatisfiedly, "Zhouzhou is your own grandson, why are you so indifferent?"
"It's not that I'm indifferent, I've heard this phenomenon from the program of the Central People's Radio. Zhou Wei said, "The program said that people all over the country are blindly running to Beijing, thinking that Beijing's medical level is so high, but in fact, because of the increase in the number of patients, the time for doctors to see a doctor is forced to be shortened to seconds." Look at it, how can such a way of seeing a doctor and efficiency ensure the medical effect?"
"I won't tell you, you are just indifferent. Qin Guizhi said angrily, "I'm going to take my grandson to Beijing to see!"
"Qin Guizhi, don't be impulsive, you are also in the medical system, you inquire and see if you can be reimbursed if you see a doctor in Beijing. You're impulsive. Zhou Wei reminded.
Qin Guizhi inquired, and sure enough, those who were not from Beijing couldn't report the account. Moreover, according to the regulations, at present, the reimbursement standard of NCMS in China has different reimbursement ratios for different places, different levels of hospitals, and different types of leukemia. In addition, the reimbursement ratio of large hospitals at the provincial and municipal levels is lower than that at the county and town levels. In addition, reimbursement can only be given if you are referred to a medical institution in another place according to the regulations, and if you seek medical treatment directly in a foreign country, you need to go back to the place of insurance within the specified time to go through the procedures.
"You also know these regulations, are you still going to Beijing?" Zhou Wei asked.
"Then don't go, just treat it locally!" Qin Guizhi said angrily.