Chapter 5 Monkey Origins
Professor Bavar rubbed his head, "I recovered a little, most of them still can't remember, but the content related to my major, I remember it very clearly, and the doctor also said that I can better recover my memory by touching familiar things before, and I think I have been to Africa before." ”
Professor Bavar said that going to Africa would help with the research project and help him recover his memory, and there was no reason why Nan Zhiqiao would not agree.
"Okay, this time I will go to Africa, Dr. Mu will lead the team, and Professor Bavar will be the deputy captain, and when I have a good time and place, I will set off. ”
Dr. Mu asked, "Mr. Nan, have you chosen the location for the clinical trial?"
Nan Zhiqiao nodded slightly, "Almost, when the Ebola outbreak broke out in West Africa last year, I contacted the Sierra Leonean side, and they have several hospitals that are willing to cooperate in this regard. ”
"It's good to have the intention of cooperating, as long as they provide the experimental population, we can solve other problems on our side, and the specific time can be determined? Dr. Mu said excitedly.
Nan Zhiqiao: "The President of Sierra Leone will visit the CDC next Wednesday and give you an answer when the time comes. ”
Dr. Mu smiled: "Diplomatic entertainment again?"
Nan Zhiqiao also smiled back, "The entertainment that can promote cooperation is still worth looking forward to." ”
Nan Zhiqiao, Dr. Mu and Professor Bawar are discussing the clinical trial of the Ebola vaccine, while Ye Zhenzhen's eyes are glued to the video of the animal experiment on the computer screen.
Professor Bavar's attention shifted to Zhen Zhen and asked, "Miss Ye, would you like to visit our laboratory animal center here?"
Ye Zhenzhen stared at the staff who were conducting animal experiments on the screen, all wearing bioprotective equipment like space suits, from clothing to code of conduct, they were all carried out in accordance with the requirements of the P4 laboratory, and if you want to visit the laboratory animal center, you must also follow such requirements.
"I want to go and see, but is it too troublesome for you, or will it affect the work of the staff inside?" Ye Zhenzhen, as a staff member of the non-Tinder No. 1 base, although she is the girlfriend of the boss Nan Zhiqiao, she also has to abide by the rules here, if she causes trouble, Zhen Zhen feels bad in her heart.
Professor Bavar smiled heartily: "Don't bother, I hope Miss Ye can also give guidance to our laboratory animal center." ”
Ye Zhenzhen thought to herself, the laboratory animal center here in the Tinder No. 1 base was originally designed by Nan Jianguo and Dr. Mu, and later after Nan Zhiqiao's reconstruction, it became its current scale, and a lot of her knowledge was also learned from Nan Zhiqiao, what better advice can she put forward?
Nan Zhiqiao also wanted to take Zhen Zhen to visit the Laboratory Animal Center, but just now he only watched part of it in the video, and after discussing the clinical trial at this time, he just had time, "Teacher Ye, let's go, let's go and have a look, and give some advice." ”
Ye Zhenzhen was also not polite, "Okay, let's take a look at the expanded laboratory animal center, how big is the scale and how many animal species there are." ”
Nan Zhiqiao, Ye Zhenzhen, Dr. Mu, Professor Bavar, and several important staff members of the team took the elevator to the laboratory animal center.
Returning to the surface from the underground lab, in the small red building next to the White Villa, is the above-ground part of the Laboratory Animal Center, where the SPF-rated Laboratory Animal Center is located.
SPF refers to experimental animals that do not have a specific pathogen, and the experimental animals here are tested for a specific pathogen before being used in the experiment.
Enter the long corridor of the animal center, flanked by rows of iron cages filled with various monkeys.
Seeing someone entering, it caused a sound, the sound of "pit, pit", one after another.
Crab-eating macaques often make this "pit pit la" sound, especially in tense or dangerous situations, and the monkeys are wary of human arrivals.
Dr. Mu introduced the types of animals in the laboratory animal center, including pigs, rats, guinea pigs, rabbits, and rodents.
In addition to cynomolgus macaques, there are other species of macaques, as well as apes.
Dressed in a biohazard suit, Ye Zhenzhen walked down the corridor with rows of healthy monkeys, sitting or jumping in their cages.
Ye Zhenzhen asked, "Where did so many experimental animals come from?"
Dr. Mu: "Experimental animals like rodents are bred in the experimental center, and most of the primates are bought, and after they are bought, they are quarantined first, and the monkeys that have no problem with quarantine will be released here to be raised." ”
"The monkeys before quarantine aren't here?"
"Yes, the monkeys before the quarantine are concentrated in another area, because those monkeys are purchased from different places, some are still imported from abroad, some are sent from farms, and some are wild monkeys, which may carry various microorganisms on their bodies. ”
"Wild monkeys?!"
In 1989, Ebola virus was detected in crab-eating macaques at a quarantine facility in Lesson, Virginia, USA.
The clinical symptoms of those monkeys were the same as those of monkeys infected with Ebola virus in animal experiments, showing symptoms such as anorexia, tearing, swollen eyelids, cough, and runny nose.
Some monkeys also have nosebleeds, subcutaneous bleeding, and blood in the stool.
After the autopsy, the internal organs of the dead monkey also seemed to melt.
The Ebola virus isolated from this outbreak is one of the five current subtypes of the Ebola virus, which is different from previous Ebola viruses in that it can infect humans without causing clinical symptoms.
Although the Reston Ebola virus does not cause clinical symptoms in humans, other subtypes of Ebola virus can cause illness and even death in humans, with a fatality rate of up to 90%.
Ye Zhenzhen asked in surprise: "These monkeys will not be imported from the Philippines, right?"
Dr. Mu: "Part of it, but we have all had serological tests before using it, and we didn't find any Ebola antibodies. ”
Dr. Mu knew that Ye was worried about the quality of the imported monkeys, after all, monkeys from the Philippines had a bad reputation.
After 1989, in 1996, the Reston type of Ebola virus was detected in crab macaques imported from the Philippines to Alice in the United States. From May to September of that year, an epidemiological investigation in the Philippines revealed that monkeys from a farm were found to be positive for Ebola virus antibodies, and all the monkeys at the farm were culled and the farm was closed, and since then there have been no reports of epidemics caused by the Reston type of Ebola virus.