At the end of the press conference, as soon as Yang Rui returned backstage, he was surrounded by people. Pen | fun | pavilion www. ｂｉｑｕｇｅ。 ｉｎｆｏ

Dean Liu asked first, regardless of it: "Yang Rui, just now I said that I want to do the second-generation PCR, is there any results, or do you have a clue, or have you just started?"

Everyone is engaged in scientific research, and this sentence translates to mean that you are ready to cash out, or are you half out of money, or are you ready to come out and cheat money?

Professor Cai also asked, "What level of research have you reached?"

Yang Rui was hugged all of a sudden, and the questions asked were all division-level figures, and he didn't dare to squeeze hard, so he could only stand obediently and answer in order: "At the beginning, the theory was just a prototype. ”

"If you don't have anything, you dare to publicize it. Wu Hongbo sighed twice, cocked his thumb and said, "You know as much as I do." ”

For Wu Hongbo, Yang Rui didn't have to be as respectful as Professor Cai, he laughed twice and replied: "At least I know the direction of the second-generation PCR." ”

Wu Hongbo thought for a while and admitted: "Count you as a winner." ”

For top scholars, directions are much more difficult than methods. In the field of scientific research, direction is basically equivalent to prophecy. Direction of this kind of thing, it's easy to get up as an afterthought, a generation of machines, a second-generation machine, a fourth-generation machine or something, just pull a military fan out, can say an afternoon, a generation of PCR, a second generation of PCR, a third generation of PCR or something, find a student from a biological laboratory to come out, you can also say eight or nine without leaving ten, but what does the fifth-generation PCR look like? How to do the sixth-generation machine, and a few people can say it for sure.

It is the car that everyone is most familiar with, what will the future look like, and a few of them make it clear: by 2050, will the car be electric, or biofuel? Or will it be a methane battery? Will it fly, will it become a circle? What is the proportion of solar energy, and what is the proportion of public transportation and private transportation? Such a direction seems to be able to be said in a few words, but if you want to guess it, how much will it cost to predict accurately?

There are many people who have come into contact with PCR, and the scholars present have more or less understood PCR, and some have even made things with PCR, but it is too difficult to say the direction of the next generation of PCR.

In fact, it was Yang Rui who said that he couldn't live without checking the information.

PCR technology will be the fastest growing technology in the next few years, it is not achieved overnight from the first generation to the second generation, there are countless intermediate and branched types, just count them, reverse PCR, direct in situ PCR - not the original flavor, indirect in situ or in situ hybridization PCR - the original flavor is too dirty, reverse transcription PCR, so many later, it is recognized as the second generation PCR, real-time fluorescence quantitative PCR.

After real-time quantitative PCR, there are methylation PCR, overlapping extension PCR, differential reverse transcription PCR, etc., I don't know how many scholars rely on PCR, do a lifetime of research, in the words of working people, that is countless people devote themselves to PCR research, dedication to life, forget to sleep and eat, and even take care of their wives and children, so they have made so many kinds of PCR.

For Yang Rui, it is not difficult for him to copy one or many kinds, but for Wu Hongbo, it is difficult to make one.

It is even more difficult to identify one of the most promising research directions.

The same real-time fluorescence quantitative PCR, there is more than one group of people who do it, and the direction of each group cannot be said to be all the same.

A good research direction is not necessarily a fast research direction, and a fast research direction is not necessarily a research direction that can meet the minimum needs.

Of course, research competitions are never easy.

Professor Cai stared at Yang Rui and asked, "Have you determined the research direction of the new generation of PCR?"

Yang Rui thought about it and said: "The real second generation will definitely not be able to do it, it is always okay to take a step forward, and the technical requirements of the second generation PCR have not been standardized at present, so we will do it first." ”

"How long will it take to make an idea?"

Yang Rui smiled dumbly: "Professor Cai, the Americans didn't ask for time, but you asked for it." ”

"It's no joke. DOE is the U.S. Department of Energy, right? This is equivalent to cooperating with provincial and ministerial units in the United States, do you know how our country defines high-level cooperation? Provincial and ministerial level and above are high-level cooperation, and that is subject to national approval. Of course, you can't be wrong, our country doesn't prohibit it after all, but you have to make the situation clear, if you lose someone, I can't protect you. Professor Cai said very seriously.

Wu Hongbo also nodded and said: "Yang Rui, Lao Cai is right here, you see in the news broadcast, our country has a good relationship with which country, the first step is to start high-level cooperation, and if the relationship with which country is not good, stop high-level dialogue, so the political meaning of this ministerial-level project is very strong, although we are all engaged in scientific research, but we can't care about politics." ”

Yang Rui was helpless by the two of them, and said: "DOE is the US Department of Energy, and I don't represent China's ministries, the dialogue must be a matter of two people, and the high-level dialogue is also a dialogue between two high-level people. ”

"Can PCR be compared to tea eggs?"

"I think it's the same, from a national point of view, it's all the same. Yang Rui forcibly broke back.

How could a few people present be fooled so simply, they all shook their heads and said: "No, no, no, not only do you have to explain, but you have to explain it quickly, in this way, let Lao Wu call the Chinese Academy of Sciences first, and the Chinese Academy of Sciences should be responsible for this matter." ”

"I also gave the leader a call. Professor Cai said very seriously.

"Don't fight here, find the embassy. Confidential lines. Shen Xingde reminded in a low voice.

"That's right...... To ......" several people inexplicably lowered their voices.

Yang Rui didn't dare to laugh if he wanted to laugh, waited for a while, and said: "Isn't the main body of this matter Huarui Company? Huarui Company is from Hong Kong." ”

Professor Cai glanced at him with sharp eyes and said: "The scientist from Sinovel Company, the biggest name is you, and the laboratory is also in China, what does it mean to say that Hong Kong is also China, this matter cannot be clever, we must report to the organization, as for how to arrange the organization, whether it is in the name of Sinovel Hong Kong Company or in any other name, this must be decided by the organization." ”

"Okay. Yang Rui thought that this seemed to be safer, so he stopped arguing.

Anyway, for him, it doesn't matter who does the follow-up studies of PCR. This thing looks simple, but you have to make it into an instrument, so that it is stable, reliable and accurate, it is not a simple thing, and it is possible to do it for three or five years.

In the history that Yang Rui is familiar with, the second-generation real-time fluorescence quantitative PCR was made in 95 years, and now the PCR technology has been developed by Yang Rui about two years in advance, and the practical first-generation PCR instrument is about five years in advance, but this does not mean that the second-generation PCR instrument will be able to be made five years in advance, after all, the development of other related technologies has not been advanced, and the so-called real-time and quantitative needs of the second-generation PCR instrument are not so urgent at present.

And the branch technology and intermediate technology before this, Yang Rui can't do so much anyway, someone is willing to do it, and Yang Rui is even more willing.

In comparison, the PCR made by Yang Rui is more like hardware, and other original or miscellaneous PCR is equivalent to an app that relies on hardware, as long as it is made, it will be beneficial to Yang Rui.

It is natural for Yang Rui to participate in the follow-up development of PCR technology through Darbeco, and as for other ideas in China, there must be a way to make them.

As long as Yang Rui is unwilling, he has the confidence to let anyone's and the country's PCR investment go down the drain.

It's just another scientific research competition.

Of course, the best possible thing is to hand over to Yang Rui in China, after all, it is his cooperation with the U.S. Department of Energy, and if China wants to rematch, it is estimated that it will not have the energy.

However, at this time, this is still a major event in the scientific research community, and Professor Cai and others can't help but support Yang Rui to return to the embassy.

……