Neeson hunched over, took two pieces of toilet paper from his butt pocket, pulled out a pen that had never left his hand, and scribbled a few words on it.

"Drug effect" and "primary cells" are written at the top by Nissen, and then dynamic mass retest.

Neeson was not prepared to take notes today, he had worked for Astra for 15 years, and before that he was a visiting professor at several universities in Norway.

Because of his familiarity with the basic biology community, Neeson is dismissive of most biologists and will attend today's lecture only because everyone else in the office is involved. As a Norwegian working in Sweden, Nissen doesn't want to be a maverick, for whatever reason.

Now, Neeson thinks he's done the right thing.

The only pity is that he didn't bring the right notebook.

He looked left and right, the people on both sides were carrying notebooks that were not thin, and they were bowing their heads to make notes, their pens were very fast, and the handwriting was sloppy, but they almost wrote down what Yang Rui said.

Neeson was a little envious.

He felt that everyone was lucky today, Yang Rui, who was born in China, obviously did not pay enough attention to his knowledge, so that he said such an important thing for no reason.

The effect of drugs on human cells is a topic that pharmaceutical companies are desperately trying to study.

How exactly the drug changes in the human body, or the so-called pharmacokinetics, I don't know how many researchers have died.

Who would have thought that a Chinese scholar would study it in this way. Moreover, it turned out to be made in the spare time of making G protein-coupled receptors.

Neeson believes Yang Rui's words, and the person who can raise the banner of G protein-coupled receptors can be said to be the top figure in biology, but he can easily study the effects of drugs?

Neeson wanted to say it was unbelievable, but listening to Yang Rui's open and detailed description, he didn't want to belittle the other party so much.

Any disparagement, at this time, should not be in the minds of researchers.

Neeson scribbled two words on the toilet paper again, then looked at the handwriting in front of him, a little annoyed.

He really didn't want to waste the opportunity in front of him.

"Hello, can you give me two pieces of paper?" Neeson said with difficulty.

Asking for help is never easy for Swedes, Norwegians and Danes.

On the other hand, helping others is an admirable quality. Without hesitation, the researcher sitting next to Neeson tore off seven or eight pages from his notebook, handed them to Neeson, and asked, "Is it enough?"

"Enough. ”

"Okay. ”

The conversation between the two men was brief, but both were satisfied with each other.

In Sweden, you can't be too proactive in helping others, you have to make sure that the other person is willing to accept help, otherwise, people who rush up to push others with a cart will cause a lot of complaints, even if they are not reprimanded.

The researcher next to Neeson had long wanted to help him, but he could only tear the paper to him after Neeson took the initiative to speak, lest Neeson just like to draw on toilet paper.

Many people see Swedish customs as a remnant of the Viking pirate culture, but the Swedes themselves don't care what others think.

They care more about whether the goal is achieved or not.

For example, the "dynamic mass remeasurement method" that Yang Rui is explaining has made many people feel closer to the target.

"In the dynamic mass reset method, what is obtained is the optical signal. This signal is the sum of all signaling pathways activated by the G protein-coupled receptor. By that alone, we can't judge the cellular response to G protein-coupled receptors, but I've got another point. Yang Rui's lecture was not vivid, but the logic was clear, advancing layer by layer, and the researchers present nodded secretly.

This is the favorite lecture mode of scientific researchers, there are dry goods but not boring, a bit like official writing.

The researchers were very short of time, and this time they were willing to come to the lecture because of Yang Rui's fame, and they naturally wanted to hear useful content.

Yang Rui is also very aware of this, and occasionally sells a pass, and does not waste everyone's time guessing, but then said: "According to my observation, optical signals are essentially different according to different cells, because different cells will express different pathways according to the stoichiometry of different signal pathway elements......"

Yang Rui explained slightly, then stopped, and said with a smile: "The earliest research on ion channels I did actually involved a little bit in this area, so when I saw the problem of the signaling pathway, I immediately had an idea. ”

Neeson and the researchers around him nodded in unison, not because they appreciated Yang Rui's acumen, but because they hoped that Yang Rui would skip the topic quickly and continue to talk.

Yang Rui did not continue to talk about the topic of his research history, but he still took into account some ion channel content.

Although several years have passed, Yang Rui's research on potassium ion channels is still world-leading.

This is also the characteristic of high-end scientific research, unless the people behind you pave the way for you with corpses one after another, otherwise, the rugged mountain road will always hinder most people from climbing.

For researchers in the industry, whether it is ion channels, optical channels or G protein-coupled receptors, it is a difficult problem to solve.

Under normal circumstances, they wouldn't have chased these complex issues. There is a lot of knowledge in the world, and no one can grasp it all.

However, the topic raised by Yang Rui is too tempting.

If the dynamic mass remeasurement method can be volatile, or even not all, as long as there can be six or seven percent of the utilitarian benefits described by Yang Rui, it will be the entire pharmaceutical industry that will be changed.

In the future, all new drug research involving G protein-coupled receptors, according to Yang Rui, is more than 5o% of future new drug research, and active substances can be screened according to this practice.

Think about it, when an active substance is found, then various studies are conducted, and then various clinical tests are conducted, at least tens of millions of dollars are the foundation, and if it is carried out to the third phase of clinical trials, it is the cost of 100 million dollars.

Although Yang Rui's dynamic mass remeasurement method cannot shorten this stage, it has the advantage of having a deeper understanding of an active substance and being able to screen out some unqualified active substances.

It's still only a part, but when you think about it, every active substance here used to cost tens of millions of dollars to sift, and the value of this part is too great.

As long as the researchers present think of this, there is not a single one who is not serious.

In fact, this method can be used not only for original drugs, but also for generic drugs that are ten times and 100 times more than that.

Generic drugs are not directly copied, you also have to have several steps behind, and then simplify and simplify, millions of expenses are inevitable.

If the total cost is calculated, the method proposed by Yang Rui now reduces the total cost even more.

A group of people looked at Yang Rui with admiration with the expression of a stupid hat.

Everyone thinks it's amazing that Yang Rui can come up with this routine, but it's stupid to say it in vain.

"Chinese researchers, it's so pure. Neeson suddenly felt the urge to talk, so he said it in Swedish.

(End of chapter)

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