Nan Zhiqiao: "If you need isolation treatment, you will be transferred to the isolation intensive care unit first for antiviral and symptomatic treatment. ”

Nan Zhiqiao became the role of the attending doctor, and the emergency doctor stopped Nan Zhiqiao and asked: "Now it's just a guess, to confirm whether it is forest encephalitis, and to collect patient specimens and send them to the district disease control, and ask them to assist in the diagnosis of the pathogen." ”

Nan Zhiqiao: "Okay, at the same time, the blood and cerebrospinal fluid will be divided into two parts, one will be sent to the district CDC, and the other will be sent to the China CDC." ”

The emergency doctor looked at Nan Zhiqiao suspiciously, the handsome man in front of him, in addition to surprising professional knowledge, also has keen judgment and domineering leadership.

The emergency doctor was curious about Nan Zhiqiao's identity and couldn't help asking, "Are you?"

"China CDC Nan Zhiqiao. ”

The emergency doctor was a young man, and when he heard Nan Zhiqiao's name, his face immediately had an expression of admiration, "It turned out to be Director Nan, who has admired the name for a long time, and I will leave the patient's pathogen testing to you." ”

The emergency doctor knows the origin of Nan Zhiqiao, he has seen the professional articles published by Nan Zhiqiao in cutting-edge magazines before, and recently on TV and the Internet, all kinds of gossip about Nanmu Group and Nan Zhiqiao are also overwhelming, and now seeing the real person, the young doctor in the emergency room is a little excited.

Nan Lishan was quickly transferred to the intensive care isolation ward, and saliva, blood, cerebrospinal fluid, and various samples were collected.

The attending physician first treats the symptoms and infuses a cryogenic fluid to lower the body temperature.

The collected patient specimens were quickly sent to the CDC laboratory, and Ye Zhenzhen had already received a call from Nan Zhiqiao, and according to Nan Zhiqiao's speculation, the pathogen was detected by PCR method.

The results soon came out, and tick-borne encephalitis virus was detected in various body fluids of Nan Lishan.

Tick-borne encephalitis virus, this virus belongs to the family Phiviridae, flavivirus, is a neurophagophilic virus, can be transmitted by tick bites, once infected with tick-borne encephalitis virus, patients will have high fever, headache, nausea, vomiting, paralysis of cervical muscles, clinically this disease is called forest encephalitis.

The pathogen was diagnosed by the CDC laboratory, and Nan Lishan's next treatment was targeted.

For the treatment of the pathogenic tick-borne encephalitis virus, ribavirin is very effective, and interferon is also used, and Nan Lishan has recovered little by little at the age of nearly 80 years old.

While treating Nan Lishan, Nan Zhiqiao thought of Grandpa Sun, who was also bitten by a tick.

Grandpa Sun was in a nursing home, and after six days of observation, just as Nan Lishan was about to be discharged from the hospital, Old Man Sun suddenly showed symptoms.

Old man Sun, who has always been healthy, suddenly had a high fever of more than 39 degrees, accompanied by headaches, back pain, muscle and joint pain, in Old Man Sun's own words, "every bone and every piece of flesh in the body is hurting".

In addition to the pain all over his body, Old Man Sun also felt nauseous and vomiting, and the skin on his neck and chest turned flushed.

Because before, Old Man Sun was infected with hantavirus because of his pet squirrel, which caused severe hemorrhagic fever and almost died, so Old Man Sun had palpitations, and when he got sick this time, Old Man Sun felt that the symptoms were similar to last time, and his heart suddenly became anxious, and he called Ye Zhenzhen.

Ye Zhenzhen also paid attention to Grandpa Sun's situation, and as soon as she received the call, she notified someone to send Grandpa Sun to the isolation ward of JS Hospital.

Before Nan Lishan was discharged from the hospital, Old Man Sun was admitted to the same hospital again, and the two old people became patients.

According to his previous experience, Nan Zhiqiao collected Old Man Sun's blood and sent it to the CDC laboratory for Ye Zhenzhen to test by PCR method.

Because Nan Lishan and Sun Laotou were bitten by ticks at the same time, although there was a five-day difference between the onset of the disease, they had the same contact history and similar initial symptoms, so the scope of testing was the same as that of Nan Lishan, which was several pathogens with ticks as the vector.

Before the test, in order to prevent other situations, Ye Zhenzhen specially prepared several more detection reagents, and found several primers for the blind sample assessment a few days ago.

Two hours later, the PCR results came out, unexpectedly, and the results were different from what Nan Zhiqiao expected.

Nan Lishan was infected with tick-borne encephalitis virus, while Sun Laotou was infected with dengue virus.

Although both viruses are arboviruses and are also in the same family and genus, they belong to different species and still have some differences.

The symptoms caused by the tick-borne encephalitis virus are also different, the forest encephalitis caused by the tick-borne encephalitis virus, as the name suggests, is dominated by encephalitis symptoms, while the symptoms caused by the dengue virus are mainly fever, rash and bleeding.

After knowing the test results, Nan Zhiqiao has always had a doubt in his heart, forest encephalitis is transmitted by tick-borne encephalitis virus through tick bites, and dengue fever is transmitted by dengue virus through mosquito vectors, and the two appear in the same population and area, which is inconsistent with the previous epidemic trend.

Is this non-conformity an exception, or is there a change in fashion trends?

Nan Zhiqiao had doubts in his heart, but there was no more evidence, what he could do now was to isolate the strains on the patient's body, do sequencing analysis, and reverse the source of the virus through the strain sequence.

Ye Zhenzhen is a research assistant in the laboratory, and Nan Zhiqiao has any ideas, and she tells Ye Zhenzhen.

The two became more and more tacitly understanding, Nan Zhiqiao mentioned a beginning, and Ye Zhenzhen knew what Nan Zhiqiao would do and purpose next.

For the experimental process, Ye Zhenzhen also put forward a few of her own opinions, which were a supplement to Nan Zhiqiao's ideas, Nan Zhiqiao carefully considered each opinion, and finally nodded in agreement.

In the following experiments, as usual, the virus strains were isolated from the patient's specimens and then the individual gene fragments were sequenced.

Before the results of the sequencing experiment came out, Nan Zhiqiao received another message.

In the past two days, various hospitals in the suburbs have received many fever patients, and after testing by the district CDC, various pathogens have been identified.

There are Japanese encephalitis virus, tick-borne encephalitis virus, and two types of rickettsia.

If the pathogen is not detected in some patient specimens, the district CDC will send the specimen to the CDC in China.

The laboratory in charge of testing in China's CDC happened to be Nan Zhiqiao's experimental group, and Ye Zhenzhen detected a spirochete in a sample that was not detected by the district CDC.

Ye Zhenzhen compiled the results fed back by the district CDC and the results of her own laboratory into a report and handed it to Nan Zhiqiao.

Nan Zhiqiao compared all the experimental results with the diagnosis of the hospital and found a strange phenomenon.

In recent times, there have been many cases of vector-borne diseases in the western suburbs, ranging from men to women, old and young.

Although the patients seem to be sporadic cases, there must be some reason why so many kinds of insect-borne diseases appear together and occur in a very concentrated area.

Nan Zhiqiao wants to find out the cause of this insect-borne disease outbreak as soon as possible, otherwise the source cannot be found, and the epidemic may spread and break out.